262-264 °C (lit.)
methanol: 25 mg/mL
Merck & Co., Inc., Kenilworth, NJ, U.S.
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6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
Dexamethasone is practically insoluble in water. It is soluble in ethanol, methanol, acetone, dioxane, and slightly soluble in chloroform. Sigma routinely tests the solubility at 50 mg/mL in ethanol with heat, yielding a clear, colorless to faint yellow solution. However, dexamethasone will precipitate out of solution as the temperature returns to room temperature. At 25 mg/mL in methanol or ethanol, a clear colorless solution is obtained without heating. The solubility of dexamethasone in DMSO is 606 mg/mL at 25°C.
Aqueous solutions of dexamethasone are stable for at least 30 days at 4°C. A stock solution at a concentration of 1mg/mL in absolute ethanol can be diluted 1:50 with sterile media and stored frozen as working aliquots.
This product has not been tested for cell culture. Please consider either Product No. D8893 or D4902, both of which are cell culture tested.
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We offer agonists, antagonists, modulators and other bioactive small molecules for immune system signaling target identification and validation, as well as a variety of antibiotics, antivirals, and antifungals.