cell culture | mammalian: suitable
H2O: 25 mg/mL, clear to slightly hazy
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
The cell lines on which this product is tested can vary from lot to lot. Some typically used cell lines are 3T3 fibroblasts, BHK, L929 and CHO.
No. This product is not sterile, but cell culture testing did not find the product to be toxic to cells.
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
Dexamethasone solutions are stable for 6 months when aliquoted stored at -20 °C in a non-defrosting freezer and protected from light. However, insufficient information is available to assess the shelf-life of solutions stored at 4°C.
The molecular weight of dexamethasone alone is 392.5 g/mol. Be sure to take the weight of the carrier into account for any calculations involving molarity of solutions.
Each vial contains 100mg of Dexamethasone. The milligrams of Dexamethasone per gram (Dexamethasone content) is listed on the Certificate of Analysis, which can be accessed through our Advanced Search Option.This information can be used to determine the conversion factor to make a solution of a given molarity.
We do not perform animal studies with our products, but it can be used in cell culture.
The tissue culture grade product is tested in water at a concentration of 25 mg/mL forming a clear to slightly hazy colorless solution.
Here is one reference that describes using Product No. D2915: Chang, C.-J., et al., Coactivator TIF1? Interacts with Transcription Factor C/EBP? and Glucocorticoid Receptor To Induce ?1-Acid Glycoprotein Gene Expression. Mol. Cell. Biol., 18(10), 5880-5887 (1998).
(2-Hydroxypropyl)-β-cyclodextrin is commonly used to get lipophilic drugs into aqueous solutions. This guest-host type complex is formed between the drug and the non-polar cavity in the HBC that results in enhanced solubility.
The carrier, (2-Hydroxypropyl)-β-cyclodextrin, has been found to be non-toxic to mice and rabbits.
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
This product can be filter sterilized through a 0.22 micron filter prior to use.
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