powder, BioReagent, suitable for cell culture, ≥97%

9α-Fluoro-16α-methylprednisolone, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, Prednisolone F, (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

biological source


product line







4-500 ng/mL


cell culture | mammalian: suitable


262-264 °C (lit.)


methanol: 25 mg/mL

shipped in


storage temp.


SMILES string




InChI key


Looking for similar products? Visit Product Comparison Guide

Related Categories


Dexamethasone is used to study apoptosis, cell signaling pathways, cell differentiation and gene expression.


25, 100, 500 mg in glass bottle
1 g in glass bottle
Bottomless glass bottle. Contents are inside inserted fused cone.

Biochem/physiol Actions

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
It is poorly metabolized in the body and has great affinity and bioavailability.

Physical form

powder 2-8 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw


To prepare 20 μg/ml stock solution, add 1ml absolute ethanol per mg product; gently swirl to dissolve. Add 49 ml sterile medium per ml of ethanol added, while mixing, to acheive final concentration of 20 μg/ml.


Health hazard





Repr. 1B


6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK Germany


Flash Point F

Not applicable

Flash Point C

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

  1. What is Product D4902, Dexamethasone, soluble in?

    Dexamethasone is practically insoluble in water. It is soluble in ethanol, methanol, acetone, dioxane and slightly soluble in chloroform. 

  2. How should I reconstitute Product D4902, Dexamethasone, for tissue culture use?

    The tissue culture grade product is dissolved in ethanol at a concentration of 1 mg/ml forming a clear, colorless solution.  It is also possible to prepare a stock solution of dexamethasone in DMSO at 1.5 mM. 

  3. Do you have references for the use of Product D4902, Dexamethasone?

    References can be found on the product detail page:Migliorati, G., et al., Dexamethasone and interleukins modulate apoptosis of murine thymocytes and peripheral T-lymphocytes. Pharmacol Res., 30(1), 43-52 (1994).Bansal, N., et al., Apoptosis: mode of cell death induced in T cell leukemia lines by dexamethasone and other agents. FASEB J. 5(2), 211-6 (1991).Shiao, R.T., et al., Dexamethasone and suramin inhibit cell proliferation and interleukin-6-mediated immunoglobulin secretion in human lymphoid and multiple myeloma cell lines. Leuk. Lymphoma, 17(5-6), 485-494 (1995).Migliorati, G., et al, Dexamethasone induces apoptosis in mouse natural killer cells and cytotoxic T lymphocytes. Immunology, 81(1), 21-26 (1994).

  4. How long is Product D4902, Dexamethasone, stable in solution?

    Dexamethasone solutions are stable for at least 30 days when stored at 4 °C and protected from light. The solution may be aliquoted and stored at -20 °C. However, insufficient information is available to assess the shelf-life of the frozen solution.

  5. What cell lines has Product D4902, Dexamethasone, been tested on?

    The cell lines on which this product is tested can vary from lot to lot. Some typically used cell lines are 3T3 fibroblasts, BHK, L929 and CHO.

  6. What is the shelf life of Product D4902, Dexamethasone?

    The product has a 5 year shelf life.

  7. Product D4902, Dexamethasone is not water soluble. Do you have a water soluble Dexamethasone?

    Product D2915 is water soluble.

  8. Can I use Product D4902, Dexamethasone, to inject into mice?

    We do not perform animal studies with our products, but it can be used in cell culture (D2915 - cell culture grade version, or USP grade product D9184).

  9. Are Products D4902 and D2915, sterile?

    No. This product is not sterile, but cell culture testing did not find the product to be toxic to cells.

  10. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

The Effect of Turmeric (Curcuma longa) Extract on the Functionality of the Solute Carrier Protein 22 A4 (SLC22A4) and Interleukin-10 (IL-10) Variants Associated with Inflammatory Bowel Disease
Mark J Cann
Nutrients, 6(10) (2014)
Isolation of Mesenchymal Stem Cells from Human Deciduous Teeth Pulp.
Tsai Aileen
BioMed Research International (2017)
Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes
Kimberly A Chapman
Molecular Genetics and Metabolism, 117, 355-362 (2016)
Multipotency and cardiomyogenic potential of human adipose-derived stem cells from epicardium, pericardium, and omentum
Wojciech Wystrychowski
Stem Cell Research & Therapy (2015)
The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights
Molecular and Cellular Endocrinology, 335(1), 2-13 (2011)
Related Content
Oxidative stress is mediated, in part, by reactive oxygen species produced by multiple cellular processes and controlled by cellular antioxidant mechanisms such as enzymatic scavengers or antioxidant modulators. Free radicals, such as reactive oxygen species, cause cellular damage via cellular.
Read More
Stem cell reprogramming protocols to generate human induced pluripotent stem cells (iPSCs) including viral and non-viral RNA based methods.
Read More

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service