Merck
All Photos(4)

D6875

Sigma-Aldrich

21-Hydroxyprogesterone

≥97% (HPLC)

Synonym(s):
DOC, 11-Deoxycorticosterone, Desoxycortone, ‘Reichstein Q’, Kendall’s desoxy compound B, 21-Hydroxy-4-pregnene-3,20-dione, 4-Pregnen-21-ol-3,20-dione, 11-Desoxycorticosterone, Cortexone
Empirical Formula (Hill Notation):
C21H30O3
CAS Number:
Molecular Weight:
330.46
Beilstein:
2062123
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

biological source

synthetic (organic)

sterility

non-sterile

assay

≥97% (HPLC)

form

powder

solubility

ethanol: 50 mg/mL, clear, colorless to very faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(=O)CO

InChI

1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1

InChI key

ZESRJSPZRDMNHY-YFWFAHHUSA-N

Gene Information

human ... SERPINA6(866)

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Packaging

500 mg in poly bottle
1, 5 g in poly bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D6875.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Carc. 2 - STOT RE 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

J E Araújo et al.
The Science of the total environment, 687, 839-848 (2019-08-16)
The adverse effects of air pollution have been long studied in the lung and respiratory systems, but the molecular changes that this causes at the central nervous system level have yet to be fully investigated and understood. To explore the
Xinliu Li et al.
Molecular microbiology, 103(4), 635-656 (2016-11-22)
Current treatment efforts for fungal infections are hampered by the limited availability of antifungal drugs and by the emergence of drug resistance. A powerful strategy to enhance the efficacy of antifungal drugs is to inhibit the molecular chaperone Hsp90. Hsp90
Shuting Liu et al.
Frontiers in microbiology, 8, 353-353 (2017-03-23)
Proteins and peptides are key components of the labile dissolved organic matter pool in marine environments. Knowing which types of bacteria metabolize peptides can inform the factors that govern peptide decomposition and further carbon and nitrogen remineralization in marine environments.
Francesca Zalfa et al.
Cell death & disease, 8(11), e3169-e3169 (2017-11-17)
The fragile X mental retardation protein (FMRP) is lacking or mutated in patients with the fragile X syndrome (FXS), the most frequent form of inherited intellectual disability. FMRP affects metastasis formation in a mouse model for breast cancer. Here we
Dennis Gürgen et al.
Hypertension (Dallas, Tex. : 1979), 61(3), 730-736 (2013-01-23)
The deoxycorticosterone acetate (DOCA)-salt mouse model exhibits adverse cardiac remodeling in male mice and cardiac protection in female mice, even when blood pressure is normalized. We hypothesized that intact mammalian target of rapamycin (mTOR) signaling is necessary for cardiac protection

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