Merck
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G6013

Sigma-Aldrich

L-Glutathione reduced

suitable for cell culture, BioReagent, ≥98.0%, powder

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Synonym(s):
Glutathione, Reduced, γ-L-Glutamyl-L-cysteinyl-glycine, GSH
Linear Formula:
H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H
CAS Number:
Molecular Weight:
307.32
Beilstein:
1729812
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

product line

BioReagent

Assay

≥98.0%

form

powder

technique(s)

cell culture | mammalian: suitable

color

white

mp

192-195 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

storage temp.

2-8°C

SMILES string

N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

InChI key

RWSXRVCMGQZWBV-WDSKDSINSA-N

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1 of 4

This Item
G6529G42513541
L-Glutathione reduced suitable for cell culture, BioReagent, ≥98.0%, powder

Sigma-Aldrich

G6013

L-Glutathione reduced

Essential+ Grade
L-Glutathione reduced BioXtra, ≥98.0%

Sigma-Aldrich

G6529

L-Glutathione reduced

Premium Grade
L-Glutathione reduced ≥98.0%

Sigma-Aldrich

G4251

L-Glutathione reduced

-
assay

≥98.0%

assay

≥98.0%

assay

≥98.0%

assay

>98% (titration)

form

powder

form

powder

form

powder

form

solid

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

-

color

white

color

white

color

white

color

white

mp

192-195 °C (dec.) (lit.)

mp

192-195 °C (dec.) (lit.)

mp

192-195 °C (dec.) (lit.)

mp

-

Amino Acid Sequence

γ-Glu-Cys-Gly

Application

May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Biochem/physiol Actions

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

related product

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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