H6034

L-Histidine

suitable for cell culture, meets EP, USP testing specifications, from non-animal source

• Synonym(s): (S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773
• Empirical Formula (Hill Notation): C₆H₉N₃O₂
• CAS Number: 71-00-1
• Molecular Weight: 155.15
• Beilstein: 84088
• EC Number: 200-745-3
• MDL number: MFCD00064315
• eCl@ss: 32160406
• PubChem Substance ID: 24895728
• NACRES: NA.26

Properties

• biological source: non-animal source
• Quality Level: 200
• Agency: meets EP testing specifications; meets USP testing specifications
• assay: 98.5-101.0%
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white to off-white
• mp: 282 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL
• application(s): peptide synthesis; pharmaceutical (small molecule)
• SMILES string: N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
• InChI key: HNDVDQJCIGZPNO-YFKPBYRVSA-N
• Gene Information: human ... CA1(759) , CA2(760)

Description

Application

L-histidine has been used as a component in agar plates containing 5-fluorocytosine (5-FC) for the selection of yeast transformants. It has also been used as a component of adult mouse keratinocyte growth medium.

Packaging

10 mg in glass bottle

25, 100 g in poly bottle

1, 25 kg

Biochem/physiol Actions

L-Histidine is an essential amino acid that binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.

Precursor of histamine by action of histidine decarboxylase.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves