I110

Ibuprofen

• Synonym(s): (±)-2-(4-Isobutylphenyl)propanoic acid, α-Methyl-4-(isobutyl)phenylacetic acid
• Empirical Formula (Hill Notation): C₁₃H₁₈O₂
• CAS Number: 15687-27-1
• Molecular Weight: 206.28
• EC Number: 239-784-6
• MDL number: MFCD00010393
• PubChem Substance ID: 329815343
• NACRES: NA.24

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• color: white to off-white
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• SMILES string: CC(C)Cc1ccc(cc1)C(C)C(O)=O
• InChI: 1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)
• InChI key: HEFNNWSXXWATRW-UHFFFAOYSA-N
• Gene Information: human ... PTGS1(5742) , PTGS2(5743)

Description

General description

Ibuprofen is a non-steroidal and anti-inflammatory drug, which finds a variety of therapeutic applications in relieving pain and inflammatory disorders.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ibuprofen has been used as a test compound in studying its removal from aqueous solutions via adsorption on titanium dioxide based multi-walled carbon nanotube membranes. It is also used as an external reference standard in order to validate the purity of the macro-cyclic peptides, an emerging therapeutic drug modality, using nuclear magnetic resonance technique (NMR).

Packaging

1, 5 g in poly bottle

Biochem/physiol Actions

Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 - H319 - H335
• Precautionary Statements: P261 - P264 - P270 - P271 - P301 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves