I7403

L-Isoleucine

from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

• Synonym(s): (2S,3S)-2-Amino-3-methylpentanoic acid
• Linear Formula: C₂H₅CH(CH₃)CH(NH₂)CO₂H
• CAS Number: 73-32-5
• Molecular Weight: 131.17
• Beilstein: 1721792
• EC Number: 200-798-2
• MDL number: MFCD00064222
• eCl@ss: 32160406
• PubChem Substance ID: 24896115
• NACRES: NA.26

Properties

• biological source: non-animal source
• Quality Level: 200
• Agency: USP/NF; meets EP testing specifications; meets JP testing specifications; meets USP testing specifications
• product line: BioXtra
• Assay: 98.5-101.0%
• form: powder
• quality: meets EP, JP, USP testing specifications
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white
• mp: 288 °C (dec.) (lit.)
• solubility: 1 M HCl: 50 mg/mL
• application(s): peptide synthesis; pharmaceutical (small molecule)
• SMILES string: CC[C@H](C)[C@H](N)C(O)=O
• InChI: 1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1
• InChI key: AGPKZVBTJJNPAG-WHFBIAKZSA-N

Description

Application

L-Isoleucine has been used as a supplement of maintenance media consisting of DMEM/F-12 for the culture of primary hepatocytes. It has also been used as a supplement for serial culture of adult murine keratinocytes.

Biochem/physiol Actions

L-Isoleucine is an essential amino acid that is synthesized from threonine. It is a branched-chain hydrophobic amino acid. L-isoleucine is an isomer of L-leucine.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves