L6152

D-Luciferin

BioXtra, ≥99% (HPLC), powder

• Synonym(s): (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid, 4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid, Firefly Luciferin
• Empirical Formula (Hill Notation): C₁₁H₈N₂O₃S₂
• CAS Number: 2591-17-5
• Molecular Weight: 280.32
• Beilstein: 30484
• EC Number: 219-981-3
• MDL number: MFCD00042929
• UNSPSC Code: 12352204
• PubChem Substance ID: 24896428
• NACRES: NA.32

Properties

• Product Name: D-Luciferin, synthetic, BioXtra, ≥99% (HPLC)
• biological source: synthetic
• Quality Level: 200
• product line: BioXtra
• Assay: ≥99% (HPLC)
• form: powder
• solubility: DMSO: 10 mg/mL, clear, colorless to faintly yellow
• storage temp.: −20°C
• SMILES string: OC(=O)[C@H]1CSC(=N1)c2nc3ccc(O)cc3s2
• InChI: 1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1
• InChI key: BJGNCJDXODQBOB-SSDOTTSWSA-N

Description

General description

D-Luciferin is mainly produced in bioluminescent organisms. It has the ability to simply circulate across the blood testis barrier, blood brain barrier and the blood placenta barrier. This small molecule is sensitive to light and oxygen. It is also sensitive to moisture in its powder form.[1]

Application

D-Luciferin has been used in the preparation of the reaction mixture for nitric oxide determination by minescence measurement.[2] It has also been used in the preparation of D-luciferin stock solution for luciferin assays.[3]

Substrate for firefly luciferase with a Km of approx 2 μM.

Other Notes

Highly purified grade with reduced levels of inhibitor relative to L 9504

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves