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Progesterone

Name: Progesterone
Brand: SIGMA

≥99% (HPLC), powder, maturation of the uterine endothelium inducer

Synonym(s):

4-Pregnene-3,20-dione

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₃₀O₂

CAS Number:

57-83-0

Molecular Weight:

314.46

NACRES:

NA.77

PubChem Substance ID:

24278618

UNSPSC Code:

51111800

EC Number:

200-350-6

MDL number:

MFCD00003658

Beilstein/REAXYS Number:

1915950

Assay:

≥99%

Form:

powder

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Properties

Product Name

Progesterone, ≥99%

biological source

synthetic (organic)

Quality Segment

300

sterility

non-sterile

assay

≥99%

form

powder

mp

128-132 °C (lit.)

solubility

chloroform: 50 mg/mL, clear, colorless to light yellow

shipped in

ambient

storage temp.

room temp

SMILES string

CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

InChI key

RJKFOVLPORLFTN-LEKSSAKUSA-N

Gene Information

human ... ABCB1(5243), AR(367), CYP2C9(1559), EBP(10682), ESR1(2099), ESR2(2100), NR3C1(2908), NR3C2(4306), PGR(5241), SERPINA6(866)
mouse ... Esr1(13982)
rat ... Ar(24208), Nr3c1(24413), Pgr(25154)

Description

Biochem/physiol Actions

Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation.

Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Steroid hormone produced by the corpus luteum.

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Show Differences

1 of 1

This Item	P3972	46665	BP449
Sigma-Aldrich P0130 Progesterone	Sigma-Aldrich P3972 Progesterone	Supelco 46665 Progesterone	BP449 Progesterone
description ≥99%	description meets USP testing specifications	description VETRANAL^®, analytical standard	description British Pharmacopoeia (BP) Reference Standard
form powder	form solid	form -	form solid
assay ≥99%	assay ≥97%	assay 99.5% (HPLC)	assay -
Quality Level 300	Quality Level 200	Quality Level 100	Quality Level -
storage temp. room temp	storage temp. -	storage temp. -	storage temp. 2-8°C
solubility chloroform: 50 mg/mL, clear, colorless to light yellow	solubility -	solubility -	solubility -
shipped in ambient	shipped in -	shipped in -	shipped in -

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pictograms

GHS08

signalword

Danger

hcodes

H351,H360FD,H362

pcodes

P202 - P260 - P263 - P264 - P270 - P308 + P313

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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