P4543

Valproic acid sodium salt

98%

• Synonym(s): 2-propylpentanoic acid sodium, Sodium 2-propylpentanoate, Sodium valproate
• Empirical Formula (Hill Notation): C₈H₁₅NaO₂
• CAS Number: 1069-66-5
• Molecular Weight: 166.19
• EC Number: 213-961-8
• MDL number: MFCD00078604
• eCl@ss: 42020819
• PubChem Substance ID: 24277744

Properties

• Quality Level: 200
• assay: 98%
• form: powder
• solubility: H₂O: 50 mg/mL
• originator: Abbott
• SMILES string: [Na+].CCCC(CCC)C([O-])=O
• InChI: 1S/C8H16O2.Na/c1-3-5-7(6-4-2)8(9)10;/h7H,3-6H2,1-2H3,(H,9,10);/q;+1/p-1
• InChI key: AEQFSUDEHCCHBT-UHFFFAOYSA-M
• Gene Information: human ... ALDH5A1(7915)

Description

Application

Valproic acid sodium salt has been used:

• in resazurin viability assay
• to systematically study its effects of clinical doses on brain volume and offspring behavior
• to study its effect on atherosclerotic lesion size

Packaging

10, 25, 100 g in glass bottle

Biochem/physiol Actions

Valproic acid is an anticonvulsant and mood-stabilizing drug. It is used to treat epilepsy and bipolar disorder. Valproic acid helps to repress the Warburg effect and the development of tumor in neuroblastoma.

Anti-convulsant that also has efficacy as a mood stabilizer in bipolar disorder.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Warning
• Hazard Statements: H302 - H361d
• Precautionary Statements: P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves