P4543

Valproic acid sodium salt

98%

• Synonym(s): 2-propylpentanoic acid sodium, Sodium 2-propylpentanoate, Sodium valproate
• Empirical Formula (Hill Notation): C₈H₁₅NaO₂
• CAS Number: 1069-66-5
• Molecular Weight: 166.19
• EC Number: 213-961-8
• MDL number: MFCD00078604
• eCl@ss: 42020819
• PubChem Substance ID: 24277744

Properties

• Quality Level: 200
• Assay: 98%
• form: powder
• solubility: H₂O: 50 mg/mL
• originator: Abbott
• SMILES string: [Na+].CCCC(CCC)C([O-])=O
• InChI: 1S/C8H16O2.Na/c1-3-5-7(6-4-2)8(9)10;/h7H,3-6H2,1-2H3,(H,9,10);/q;+1/p-1
• InChI key: AEQFSUDEHCCHBT-UHFFFAOYSA-M
• Gene Information: human ... ALDH5A1(7915)

Description

Application

Valproic acid sodium salt has been used:

• in resazurin viability assay
• to systematically study its effects of clinical doses on brain volume and offspring behavior
• to study its effect on atherosclerotic lesion size

Biochem/physiol Actions

Valproic acid is an anticonvulsant and mood-stabilizing drug. It is used to treat epilepsy and bipolar disorder. Valproic acid helps to repress the Warburg effect and the development of tumor in neuroblastoma.

Anti-convulsant that also has efficacy as a mood stabilizer in bipolar disorder.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Warning
• Hazard Statements: H302 - H361d
• Precautionary Statements: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves