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P6744

Sigma-Aldrich

Picric acid solution

1.3% in H2O (saturated)

Synonym(s):
2,4,6-Trinitrophenol
Linear Formula:
(O2N)3C6H2OH
CAS Number:
Molecular Weight:
229.10
Beilstein:
423400
MDL number:
PubChem Substance ID:
NACRES:
NA.47

form

liquid

Quality Level

concentration

1.3% in H2O (saturated)

color

yellow to very dark yellow

density

1.080 g/cm3

application(s)

hematology
histology

storage temp.

room temp

SMILES string

Oc1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O

InChI

1S/C6H3N3O7/c10-6-4(8(13)14)1-3(7(11)12)2-5(6)9(15)16/h1-2,10H

InChI key

OXNIZHLAWKMVMX-UHFFFAOYSA-N

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General description

Picric acid is a polynitrated aromatic acid. It dissolves in water to form a solution with low pH (pH 2.0). It interacts with basic groups of proteins, forms salts and coagulates them. Fixation with picric acid gives a bright stain, but there might be a loss of nucleic acids due to the low pH of the solution.

Application

Picric acid solution can be used as a colorimetric reagent in creatinine determination assay. It is a general cytoplasmic stain, connective tissue fiber stain and a fixative for tissues.

Packaging

1 gal in poly bottle

Supplementary Hazards

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Andre Picot, P. Grenouillet
Safety in the Chemistry and Biochemistry Laboratory (1994)
Xin Is a Marker of Skeletal Muscle Damage Severity in Myopathies
The American Journal of Pathology, 183 (2013)
Regulator of G-Protein Signaling-5 Is a Marker of Hepatic Stellate Cells and Expression Mediates Response to Liver Injury
Arya Bahrami
PLoS ONE (2014)
Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution
Benjamin Le Calve
Oncotarget (2016)
John D. Bancroft
Theory and Practice of Histological Techniques (2008)

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