Prilocaine hydrochloride

≥98% (TLC)

N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride
Empirical Formula (Hill Notation):
C13H20N2O · HCl
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


≥98% (TLC)



SMILES string




InChI key


Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Used for local nerve block and for spinal anesthesia; pharmacological properties are similar to those of lidocaine.

Features and Benefits

This compound was developed by AstraZeneca,. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here,.
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here, to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point F

Not applicable

Flash Point C

Not applicable

Certificate of Analysis

Certificate of Origin

K Nakamura et al.
Canadian journal of anaesthesia = Journal canadien d'anesthesie, 46(5 Pt 1), 476-482 (1999-06-01)
To determine whether prilocaine, a local anesthetic, induces apoptosis in osteoblastic cells. After reaching subconfluence, human osteoblastic Saos-2 and MG63 cells and mouse osteoblastic MC3T3-E1 cells were exposed for 48 hr to varying concentrations of prilocaine up to 10 mM...
P K Gupta et al.
British journal of anaesthesia, 110(5), 831-836 (2013-02-09)
Our aim was to estimate the ED95 of prilocaine 1% w/v for femoral nerve block. This two-stage dose-finding sequential clinical trial followed an adaptive design based on the continual reassessment method (CRM). Adult patients undergoing Vastus medialis muscle biopsy under...
Nezih Sertoz et al.
Foot & ankle international, 34(1), 85-90 (2013-02-07)
The objective of the present study was to explore the effects of deficiencies in glucose regulation on the onset, regression, and block performance times in a group of patients with diabetes-related foot problems. Forty-eight patients with American Society of Anesthetists...
Stephanie C J Keating et al.
PloS one, 7(9), e44437-e44437 (2012-09-13)
Ear tattooing is a routine procedure performed on laboratory, commercial and companion rabbits for the purpose of identification. Although this procedure is potentially painful, it is usually performed without the provision of analgesia, so compromising animal welfare. Furthermore, current means...
Austin Larson et al.
Pediatric emergency care, 29(3), 377-379 (2013-03-07)
Topical anesthetics are commonly used in many health care settings and for many clinical conditions. However, there are a number of potential adverse effects associated with their use. Their widespread administration can convey a false sense of security and failure...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service