Merck
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PZ0284

Sigma-Aldrich

PF-04753299

≥98%

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Synonym(s):
α(R)-N-Hydroxy-α-methyl-α-(methylsulfonyl)-[1,1′-biphenyl]-4-butanamide, (+)-(2R)-4-(Biphenyl-4-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2R)-4-Biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, PF 04753299, PF-4753299
Empirical Formula (Hill Notation):
C18H21NO4S
CAS Number:
Molecular Weight:
347.43
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥98%

form

powder

color

white to light brown

solubility

DMSO: 20 mg/mL, clear

storage temp.

room temp

SMILES string

O=C(NO)[C@@](S(=O)(C)=O)(C)CCC(C=C1)=CC=C1C2=CC=CC=C2

InChI

1S/C18H21NO4S/c1-18(17(20)19-21,24(2,22)23)13-12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11,21H,12-13H2,1-2H3,(H,19,20)/t18-/m1/s1

InChI key

GDYIQUFNICPYHF-GOSISDBHSA-N

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PF-04753299 ≥98%

Sigma-Aldrich

PZ0284

PF-04753299

PF-02413873 ≥98% (HPLC)

Sigma-Aldrich

PZ0367

PF-02413873

PF-05020182 ≥98% (HPLC)

Sigma-Aldrich

PZ0278

PF-05020182

CP-471474 ≥98% (HPLC)

Sigma-Aldrich

PZ0137

CP-471474

form

powder

form

powder

form

powder

form

powder

manufacturer/tradename

Pfizer®

manufacturer/tradename

Pfizer®

manufacturer/tradename

Pfizer®

manufacturer/tradename

Pfizer®

color

white to light brown

color

white to beige

color

white to beige

color

white to off-white

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: ≥20 mg/mL

originator

Pfizer

originator

Pfizer

originator

Pfizer

originator

Pfizer

Biochem/physiol Actions

PF-04753299 is a potent and selective inhibitor of LpxC (UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase) that is effective in a murine of gram-negative bacteria infection model.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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