High mobility group box 1 (HMGB1) is a nuclear protein that belongs to the damage-associated molecular pattern (DAMP) family. It is located on human chromosome 13q12.
Anti-HMGB1 Antibody detects endogenous levels of total HMGB1 protein.
The antiserum was produced against synthesized peptide derived from human HMGB1.
Immunogen Range: 131-180
High mobility group box 1 (HMGB1) is involved in bone remodeling and ectopic calcification pathogenesis. It initiates neuroinflammation after epileptogenic injuries. HMGB1 also binds to chromatin and modulates gene transcription.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.