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FGF-2 human

recombinant, expressed in insect cells, ≥85% (SDS-PAGE)


biological source



expressed in insect cells


≥85% (SDS-PAGE)


frozen liquid

mol wt

~32.5 kDa


pkg of 5 μg

storage condition

avoid repeated freeze/thaw cycles


350 μg/mL


colorless to clear

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.


Gene Information

human ... FGF2(2247)


FGF2 (fibroblast growth factor 2)-human has been used to study the role of FGF2 on steroidogenesis and survival of cultured buffalo granulosa cells. It has been used as a control to study activated α2-macroglobulin mediated Müller glial cell migration.

Biochem/physiol Actions

Acidic fibroblast growth factor (FGF-1) and basic fibroblast growth factor (FGF-2) are ubiquitous cytokines found in many tissues. They have effects on multiple cell types derived from mesoderm and neuroectoderm, including endothelial cells. FGF proteins are small peptides of 155 to 268 amino acid residues. The degree of sequence identity between different family members is 30-60 % in a "central domain" of approx. 120 amino acids. This domain confers to FGFs a common tertiary structure and the ability to bind to heparin. Secreted FGFs signal to target cells by binding and activating cell-surface tyrosine kinase FGF receptors (FGFRs; 6, 7). The function of FGFs and FGFRs during embryonic development and adult physiology has been addressed by gain- and loss-of-function experiments in several animal model organisms. These studies have shown that FGFs act as key regulators of developmental events.

Physical form

Clear and colorless frozen liquid solution

Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Storage Class Code

10 - Combustible liquids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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Li Liu et al.
Biomaterials, 35(24), 6259-6267 (2014-05-09)
Nanofibrous gelatin substrates are suited for long-term expansion of human pluripotent stem cells (hPSCs) under feeder- and serum-free culture conditions. A combinatorial library with different sets of processing parameters was established to assess the culture performance of hPSCs on nanofibrous
Fibroblast growth factor-2.
Nugent MA and Iozzo RV
The International Journal of Biochemistry & Cell Biology, 32, 115-120 (2000)
L De Moerlooze et al.
Development (Cambridge, England), 127(3), 483-492 (2000-01-13)
The fibroblast growth factor receptor 2 gene is differentially spliced to encode two transmembrane tyrosine kinase receptor proteins that have different ligand-binding specificities and exclusive tissue distributions. We have used Cre-mediated excision to generate mice lacking the IIIb form of
S R Mishra et al.
Research in veterinary science, 108, 98-111 (2016-09-25)
The present study investigated the expression and localization of FGF and its functional receptors in the follicle of buffalo and the treatment of FGF2 on mRNA expression of CYP19A1 (aromatase), PCNA, and BAX (BCL-2 associated X protein) in cultured buffalo
Toshihiro Uesaka et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(27), 9879-9888 (2015-07-15)
Elucidation of the cellular identity of neuronal precursors provides mechanistic insights into the development and pathophysiology of the nervous system. In the enteric nervous system (ENS), neurogenesis persists from midgestation to the postnatal period. Cellular mechanism underlying the long-term neurogenesis

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