One of the common difficulties with natural product and other multi-step syntheses is the need to render one functional group inert to a particular reagent, while keeping another group open for further chemical elaboration. Despite the great advances made in the involved synthesis of multifunctional products, chemoselectivity in functional group transformations remains a critical issue in organic synthesis. Unfortunately, there is no perfect protecting group applicable to any functional group in any situation. Thus, the chemist needs a handy toolbox of selective and efficient protection reagents that can be applied and easily removed under a variety of conditions by a deprotection reagent.
We are pleased to offer an unmatched portfolio of alcohol protecting groups, amine protecting groups, carbonyl protecting groups, carboxylic acid protecting groups, phosphate protecting groups, and terminal alkyne protecting groups to make your breakthroughs feel closer than ever. Selected highlights are:
It is equally important to be able to remove the protecting group at the end of the synthesis. Our portfolio of deprotecting agents will help you get to your desired molecule to reach new scientific frontiers.