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Merck

Single-Use Mixers

Ranging from 10 to 3000 L, our single-use mixers have been designed to meet the broadest range of requirements. Mobius® single-use mixers efficiently blend pharmaceutical ingredients and prepare process solutions like buffers and media. Unlike traditional stainless steel mixers which require downtime for cleaning processes, Mobius® single-use mixers minimize it with uncompromised mix quality. For antibody drug conjugate manufacturing, the Mobius® ADC Reactor is specifically designed for the key conjugation step.

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Three white mobius MIX single-use mixers ranging in size from big to small.

Mobius® MIX: the mixing solution of choice for gentle mixing applications such as protein and shear-sensitive product homogenization

  • Available in 10 L, 50 L, 100 L, 200 L, 500 L, and 1,000 L sizes (jacketed stainless steel or plastic depending on size)
  • Fast, easy setup and use
  • Compact footprint and mobile carrier construction for enhanced flexibility
  • Instant-on electronics with no warmup needed
Three different sized stainless steel Mobius® Power MIX single-use mixers; medium on left, large in center, and small on right.

Mobius® Power MIX: the mixing solution of choice for hard-to-dissolve materials and buffer preparation

  • Available in 100 L, 200 L, 500 L, 1,000 L, 2,000 L, 2,500 L, and 3,000 L (jacketed stainless steel or plastic depending on size)
  • Stainless steel versions have wide doors that open to one half the mixer's diameter for easy bag loading
  • Optional integrated load cells and temperature sensor on stainless steel versions
Three sizes of Mobius<sup>®</sup> ADC reactors

Mobius® ADC Reactor: A SCALABLE FAMILY OF SINGLE-USE MIXING SYSTEMS PERFECTED FOR BIOCONJUGATION

  • Available in 10 L, 100 L, and 500 L sizes
  • Single-use components with proven compatibility with solvents such as DMAc and DMSO, ensuring product quality 
  • Designed with the requirements of conjugation in mind, with addition ports for tailored material handling
Ready to connect, stainless steel control box on the left and stainless steel smart control box with HMI on the right

Control Boxes

Mobius® mixers and Mobius® ADC Reactors can be monitored and controlled locally or remotely with  the Ready to Connect control box.

For Mobius® MIX and Power MIX, the smart control box with Bio4C ACE™ Control Software enables remote monitoring of critical process parameters, supplies advanced process control, and facilitates regulatory compliance during mixing operations.

Single-use mixer bags are made either with PureFlex™ or with Ultimus® film. The PureFlex™ family of single-use process container films are high purity, medical grade and coextruded to provide strength, flexibility, excellent gas barrier performance, and inert contact. Additionally, Ultimus® Film was designed for your more challenging single-use bioprocessing liquid applications, increasing durability while maintaining the ease of handling, flexibility, and conformity that single-use bioprocessing demands.



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