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Bruno M Andrade et al.
PloS one, 10(6), e0127561-e0127561 (2015-06-04)
Skeletal muscle injury is the most common problem in orthopedic and sports medicine, and severe injury leads to fibrosis and muscle dysfunction. Conventional treatment for successive muscle injury is currently controversial, although new therapies, like cell therapy, seem to be
Xiangwen Peng et al.
Frontiers in cell and developmental biology, 8, 323-323 (2020-06-12)
Previous studies have demonstrated that inhibition of canonical Wnt signaling promotes zebrafish heart regeneration and that treatment of injured heart tissue with the Wnt activator 6-bromo-indirubin-3-oxime (BIO) can impede cardiomyocyte proliferation. However, the mechanism by which Wnt signaling regulates downstream
Giuliana Magri et al.
Nature immunology, 15(4), 354-364 (2014-02-25)
Innate lymphoid cells (ILCs) regulate stromal cells, epithelial cells and cells of the immune system, but their effect on B cells remains unclear. Here we identified RORγt(+) ILCs near the marginal zone (MZ), a splenic compartment that contains innate-like B
Pablo J Giraudi et al.
Experimental and molecular pathology, 98(1), 85-92 (2014-12-24)
Non-alcoholic fatty liver disease is characterized by an initial accumulation of triglycerides that can progress to non-alcoholic steatohepatitis, which can ultimately evolve to cirrhosis and hepatocellular carcinoma. Hepatic stellate cells play a key role in liver fibrogenesis by an increased
Sujatha Kandasamy et al.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 46(3), 659-666 (2015-09-29)
Ten bacterial strains that utilize cyanide (CN) as a nitrogen source were isolated from cassava factory wastewater after enrichment in a liquid media containing sodium cyanide (1 mM) and glucose (0.2% w/v). The strains could tolerate and grow in cyanide
Charles T Putman et al.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 40(7), 671-682 (2015-06-04)
This study tested the hypothesis that elevating the intracellular phosphorylation potential (IPP = [ATP]/[ADP]free) within rat fast-twitch tibialis anterior muscles by creatine (Cr) loading would prevent fast-to-slow fibre transitions induced by chronic low-frequency electrical stimulation (CLFS, 10 Hz, 12 h/day).
Bijan Roy et al.
The Journal of organic chemistry, 78(3), 1306-1310 (2013-01-12)
Two new anthracene-functionalized fluorescent tris-imidazolium salts have been synthesized, characterized, and proven to be selective sensors for picric acid, which is a common constituent of many powerful explosives. Theoretical studies revealed an unusual ground-state electron transfer from picrate anion to
To Carlos Fung et al.
Forensic science international, 212(1-3), 143-149 (2011-07-09)
Cyanoacrylate fuming is one of the most common techniques employed for the detection of latent fingermarks on non-porous surfaces such as plastic and glass. The technique is generally applied by exposing items of interest to the vapours generated by heating
Omer Ziv et al.
PLoS computational biology, 11(10), e1004453-e1004453 (2015-10-17)
Neural stem cells (NSCs) are progenitor cells for brain development, where cellular spatial composition (cytoarchitecture) and dynamics are hypothesized to be linked to critical NSC capabilities. However, understanding cytoarchitectural dynamics of this process has been limited by the difficulty to
Vanessa Reame et al.
Biology of reproduction, 91(6), 151-151 (2014-10-24)
This study compares the impact of obesogenic environment (OE) in six different periods of development on sperm parameters and the testicular structure of adult rats and their correlations with sex steroid and metabolic scenario. Wistar rats were exposed to OE
Pooja Shivshankar et al.
Journal of molecular and cellular cardiology, 76, 84-93 (2014-08-17)
Adverse remodeling following myocardial infarction (MI) leading to heart failure is driven by an imbalanced resolution of inflammation. The macrophage cell is an important control of post-MI inflammation, as macrophage subtypes secrete mediators to either promote inflammation and extend injury
Hang Zhou et al.
Molecular brain, 8, 42-42 (2015-07-18)
The density of functional synapses is an important parameter in determining the efficacy of synaptic transmission. However, how functional presynaptic terminal density is regulated under natural physiological conditions is still poorly understood. We studied the factors controlling the density of presynaptic
S Gowri et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 81(1), 257-260 (2011-07-15)
A new organic nonlinear optical material L-tryptophanium picrate was synthesized. From the powder XRD pattern the various planes of reflections were identified. The grown crystals were subjected to FT-IR and (1)H NMR spectral analyses to confirm the synthesized compound. Thermal
Federica Ianni et al.
Journal of pharmaceutical and biomedical analysis, 116, 40-46 (2015-01-27)
In two-dimensional HPLC (2D-HPLC) "heart-cut" applications, two columns are connected in series via a switching valve and volume fractions from the "primary" column are re-injected on the "secondary" column. The heart-cut 2D-HPLC system here described was implemented by connecting a
Denis Babici et al.
American journal of physiology. Heart and circulatory physiology, 319(1), H222-H234 (2020-06-13)
Protection against increased vascular stiffness in young women is lost after menopause. However, little is known about vascular stiffness in older, premenopausal females, because most of the prior work has been conducted in rodents, which live for only 1-3 yr
Zhonghua Xiang et al.
Macromolecular rapid communications, 33(14), 1184-1190 (2012-04-18)
Three porous luminescent covalent--organic polymers (COPs) have been synthesized through self-polycondensation of the monomers of tris(4-bromophenyl)amine, 1,3,5-tris(4-bromophenyl)benzene, and 2,4,6-tris-(4-bromo-phenyl)-[1,3,5]triazine by using Ni-catalyzed Yamamoto reaction. All the COP materials possess not only high Brunauer-Emmett-Teller (BET) specific surface area of about 2000
Jeremy V Camp et al.
Journal of virology, 89(17), 8733-8748 (2015-06-13)
Infection of the lower respiratory tract by influenza A viruses results in increases in inflammation and immune cell infiltration in the lung. The dynamic relationships among the lung microenvironments, the lung, and systemic host responses during infection remain poorly understood.
K M Fernandes et al.
Medical and veterinary entomology, 29(3), 245-254 (2015-05-15)
The mosquito Stegomyia aegypti (=Aedes aegypti) (Diptera: Culicidae) is a vector for the dengue and yellow fever viruses. As blood digestion occurs in the midgut, this organ constitutes the route of entry of many pathogens. The effects of the insecticide
Dustin Staloch et al.
Journal of molecular medicine (Berlin, Germany), 93(10), 1085-1093 (2015-07-05)
The current study aims to identify the pro-fibrogenic role of Gremlin, an endogenous antagonist of bone morphogenetic proteins (BMPs) in chronic pancreatitis (CP). CP is a highly debilitating disease characterized by progressive pancreatic inflammation and fibrosis that ultimately leads to
Wiebke Janssen et al.
BioMed research international, 2015, 438403-438403 (2015-02-11)
The serotonin (5-HT) pathway was shown to play a role in pulmonary hypertension (PH), but its functions in right ventricular failure (RVF) remain poorly understood. The aim of the current study was to investigate the effects of Terguride (5-HT2A and
Martin Burdel et al.
Journal of separation science, 36(5), 932-938 (2013-02-06)
Three modes of liquid-liquid based microextraction techniques--namely auxiliary solvent-assisted dispersive liquid-liquid microextraction, auxiliary solvent-assisted dispersive liquid-liquid microextraction with low-solvent consumption, and ultrasound-assisted emulsification microextraction--were compared. Picric acid was used as the model analyte. The determination is based on the reaction
Meadhbh Á Brennan et al.
Biomedical materials (Bristol, England), 10(4), 045019-045019 (2015-08-05)
A major limitation of the 2D culture systems is that they fail to recapitulate the in vivo 3D cellular microenvironment whereby cell-cell and cell-extracellular matrix (ECM) interactions occur. In this paper, a biomaterial scaffold that mimics the structure of collagen
Munevver Acikkol et al.
Journal of AOAC International, 98(3), 760-766 (2015-06-19)
A highly specific and selective analytical method using LC/MS/MS for the quantitative determination of ethyl glucuronide (EtG) in urine was developed and fully validated. Since the determination of EtG in urine may be possible days after the elimination of alcohol
Secil Koseoglu et al.
Blood, 126(5), 651-660 (2015-05-23)
Platelet activation results in profound morphologic changes accompanied by release of granule contents. Recent evidence indicates that fusion of granules with the plasma membrane during activation provides auxiliary membrane to cover growing actin structures. Yet little is known about how
Manuel Valero et al.
Nature neuroscience, 18(9), 1281-1290 (2015-07-28)
Sharp-wave ripples represent a prominent synchronous activity pattern in the mammalian hippocampus during sleep and immobility. GABAergic interneuronal types are silenced or fire during these events, but the mechanism of pyramidal cell (PC) participation remains elusive. We found opposite membrane
Beatriz Martín-Fernández et al.
PloS one, 9(10), e111104-e111104 (2014-10-30)
Aldosterone administration in rats results in several cardiac alterations. Previous studies have demonstrated that proanthocyanidins, phenolic bioactive compounds, have cardioprotective effects. We studied the potential beneficial effects of the proanthocyanidin-rich almond skin extract (PASE) on the cardiac alterations induced by
Shuangping Zhao et al.
Nephrology (Carlton, Vic.), 20(9), 646-653 (2015-05-07)
The aim of this study was to investigate the effect of neutrophil gelatinase-associated lipocalin (NGAL) on the rat cecal ligation and puncture (CLP)-induced sepsis and the possible mechanism. Thirty male Sprague-Dawley rats underwent CLP as sepsis models and were randomized
Kenneth W Jackson et al.
Neoplasia (New York, N.Y.), 17(1), 43-54 (2015-01-28)
Tumor microenvironments (TMEs) are composed of cancer cells, fibroblasts, extracellular matrix, microvessels, and endothelial cells. Two prolyl endopeptidases, fibroblast activation protein (FAP) and prolyl oligopeptidase (POP), are commonly overexpressed by epithelial-derived malignancies, with the specificity of FAP expression by cancer
Jia Qi et al.
Nature communications, 5, 5390-5390 (2014-11-13)
Electrical stimulation of the dorsal raphe (DR) and ventral tegmental area (VTA) activates the fibres of the same reward pathway but the phenotype of this pathway and the direction of the reward-relevant fibres have not been determined. Here we report
Charoen Kaitwatcharachai et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 94 Suppl 4, S135-S139 (2011-11-03)
Previous studies showed that high glucose in dialysate could interfere with creatinine measurement. This error might produce some mistakes in peritoneal dialysis (PD) treatment. The correction of creatinine is essentially needed. Creatinine powder diluted in 0.1 N HCl was used
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