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Leonie F A Huitema et al.
European journal of pharmacology, 542(1-3), 48-53 (2006-07-11)
Sodium nitroprusside (SNP) is a nitric oxide (NO) donor drug, which is therapeutically used as a vasodilating drug in heart transplantations. In our previous study it was found that SNP at a concentration of 100 microM inhibited mineralization in a...
Xianwen Mi et al.
Analytical chemistry, 84(2), 939-946 (2011-12-07)
The key factors that control the spread and mortality rate of tuberculosis (TB) are rapid detection and diagnosis. However, the current detection of Mycobacterium tuberculosis (M. tuberculosis) cannot meet the recommended requirements for clinical diagnosis in turnaround time. In this...
Ashish Pathak et al.
Journal of hazardous materials, 171(1-3), 273-278 (2009-07-10)
The potential of indigenous iron-oxidizing microorganisms enriched at initial neutral pH of the sewage sludge for bioleaching of heavy metals was investigated at initial neutral pH of the sludge using ammonium ferrous sulfate (FAS) and ferrous sulfate (FS) as an...
Mayara Marinovic Baccan et al.
Journal of inorganic biochemistry, 107(1), 34-39 (2011-12-17)
The antioxidant activity of flavonoids may involve their ability to complex body iron in non-redox-active forms. In this study, it was found that the catechol flavonoids rutin and quercetin are able to suppress redox-active labile plasma iron (LPI) in both...
Seong-Ryong Lee et al.
Phytotherapy research : PTR, 17(3), 206-209 (2003-04-03)
The aim of this study was to compare the protective effects of green tea polyphenol (-)-epigallocatechin gallate (EGCG) and other well-known antioxidants on the lipid peroxidation in gerbil brain homogenates. Oxidative stress was induced by H2O2 (10 mM) or ferrous...
S Brindha et al.
Physics in medicine and biology, 47(11), N153-N158 (2002-07-11)
Radiation dosimetry deals with the determination of absorbed dose to the medium exposed to ionizing radiation. Chemical dosimetry depends on oxidation or reduction of chemicals by ionizing radiation. A ferrous ammonium sulfate benzoic acid xyelenol orange (FBX) dosimeter based on...
M K Semwal et al.
Physics in medicine and biology, 47(12), N179-N183 (2002-07-18)
The FBX aqueous chemical dosimeter contains 0.2 mol m(-3) ferrous ammonium sulphate, 5.0 mol m(-3) benzoic acid and 0.20 mol m(-3) xylenol orange in 40.0 mol m(-3) sulphuric acid. The dosimeter can measure photon and electron doses in the range...
Ozcan Erel
Clinical biochemistry, 37(2), 112-119 (2004-01-17)
Oxidative damage of biomolecules occurs as a result of potent free radical reactions. In this study, a novel, colorimetric and fully automated method for measuring total antioxidant response (TAR) against potent free radical reactions is described. Potent free radical reactions...
Tae-Young Jung et al.
Phytotherapy research : PTR, 21(10), 960-964 (2007-07-03)
Gastrodia elata (GE) Blume, a traditional herbal agent, has been used mainly in anticonvulsive treatment in Asia. Recently, extracts of GE were evaluated for their potential as neuroprotectives and antioxidants. This study was designed to examine the antioxidant effect of...
Cinzia Signorini et al.
Pediatric research, 63(3), 287-291 (2008-02-22)
Nonprotein-bound iron (NPBI) and F2-isoprostanes, reliable markers of oxidative stress, are increased in plasma of newborns and inversely correlated to the gestational age. Because NPBI represents a pro-oxidant stimulus in plasma, we test the hypothesis that the entity of lipid...
Matthew D Krzyaniak et al.
Biochemistry, 52(47), 8430-8441 (2013-10-31)
Tyrosine hydroxylase is a nonheme iron enzyme found in the nervous system that catalyzes the hydroxylation of tyrosine to form l-3,4-dihydroxyphenylalanine, the rate-limiting step in the biosynthesis of the catecholamine neurotransmitters. Catalysis requires the binding of three substrates: tyrosine, tetrahydrobiopterin...
Michaela Hohnholt et al.
Neurochemical research, 35(8), 1259-1268 (2010-05-15)
The oligodendroglial cell line OLN-93 was used as model system to investigate the consequences of iron deprivation or iron excess on cell proliferation. Presence of ferric or ferrous iron chelators inhibited the proliferation of OLN-93 cells in a time and...
Arnold L Demain et al.
Applied microbiology and biotechnology, 73(1), 55-59 (2006-04-20)
When tetanus toxin is made by fermentation with Clostridium tetani, the traditional source of iron is an insoluble preparation called reduced iron powder. This material removes oxygen from the system by forming FeO(2) (rust). When inoculated in a newly developed...
Hyung Lee et al.
Journal of neurosurgical anesthesiology, 17(3), 144-148 (2005-07-23)
This study compared the effectiveness of propofol with that of trolox and melatonin for reduction of lipid peroxidation in vitro. Lipid peroxidation was induced by addition of kainic acid (KA; 10 mM), hydrogen peroxide (H2O2; 10 mM), or ferrous ammonium...
Maki Kaneko et al.
Journal of proteome research, 3(5), 983-987 (2004-10-12)
Recombinant holo Thermus thermophilus [7Fe-8S] ferredoxin was synthesized by cloning from Thermus thermophilus HB8 gene. A specific sequence (Pro-His-Val-Ile) at the N-terminus of the recombinant ferredoxin was determined by a rapid and highly sensitive mass spectral method using a novel...
Hassan Abbas et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 313, 106722-106722 (2020-04-06)
Inflammation is central in disease pathophysiology and accurate methods for its detection and quantification are increasingly required to guide diagnosis and therapy. Here we explored the ability of Fast Field-Cycling Magnetic Resonance (FFC-MR) in quantifying the signal of ultra-small superparamagnetic...
Yu-Jung Chang et al.
Nutrition (Burbank, Los Angeles County, Calif.), 21(4), 520-524 (2005-04-07)
This study examined whether iron accumulated in ferritin-producing recombinant microbes is bioavailable to rats with iron deficiency. Rats induced with iron deficiency were treated with iron preparations of ferrous ammonium sulfate, horse spleen ferritin, control yeast, and ferritin-producing recombinant yeast...
Ubon Cha'on et al.
Toxicological sciences : an official journal of the Society of Toxicology, 96(1), 194-201 (2006-12-19)
The aim of this study is to identify the biochemical mechanism of phosphine toxicity and resistance, using Caenorhabditis elegans as a model organism. To date, the precise mode of phosphine action is unclear. In this report, we demonstrate the following...
Cysteine Deprivation Targets Ovarian Clear Cell Carcinoma Via Oxidative Stress and Iron-Sulfur Cluster Biogenesis Deficit.
Novera, et al.
Antioxidants & Redox Signaling, 33, 1191-1208 (2020)
Kazumasa Kumamoto et al.
Free radical research, 39(9), 987-993 (2005-08-10)
Identification of free radicals was performed for the reaction mixtures of autoxidized 1,2-dilinoleoylphosphatidylcholine (DLPC) with ferrous ions (or DLPC hydroperoxide with ferrous ions) and of DLPC with soybean lipoxygenase using electron spin resonance (ESR), high performance liquid chromatography (HPLC)--ESR and...
Jung Suh et al.
Free radical biology & medicine, 34(10), 1306-1314 (2003-05-03)
The combination of ascorbate, transition metal ions, and hydrogen peroxide (H(2)O(2)) is an efficient hydroxyl radical generating system called "the Udenfriend system." Although the pro-oxidant role of ascorbate in this system has been well characterized in vitro, it is uncertain...
Melanie T M Davidson et al.
Medical physics, 36(4), 1340-1350 (2009-05-29)
Granulated cane sugar has been used as a dosimetric material to report dose in high dose accidental irradiations. The purpose of this study was to assess whether clinical dosimetry is also plausible with such a commonly available material. The behavior...
Y J Tseng et al.
Medical physics, 32(4), 1017-1023 (2005-05-18)
A least-squares error minimization approach was adopted to assess ferric ion diffusion coefficient of Fricke-agarose gels. Ferric ion diffusion process was modeled as a Gaussian-shaped degradation kernel operating on an initial concentration distribution. Diffusion coefficient was iteratively determined by minimizing...
F R Cassee et al.
Inhalation toxicology, 14(12), 1215-1229 (2002-11-28)
In the present study the effects of a 3-day inhalation exposure to model compounds for ambient particulate matter were investigated: ammonium bisulfate, ammonium ferrosulfate, and ammonium nitrate, all components of the secondary aerosol fraction of ambient particulate matter (PM), and...
Zhenghong Zhang et al.
Animal science journal = Nihon chikusan Gakkaiho, 82(2), 244-250 (2011-07-07)
Vascular endothelial growth factor (VEGF)-dependent angiogenesis is crucial for corpus leteum formation and their functional maintenance in mammalian ovaries. The present study was designed to test the hypothesis that hypoxia-inducible factor (HIF)-1α-mediated transcriptional activation contributes to the increased expression of...
Jennifer-C Kuchernig et al.
Phytochemistry, 72(14-15), 1699-1709 (2011-07-26)
Glucosinolates, amino acid-derived thioglycosides found in plants of the Brassicales order, are one of the best studied classes of plant secondary metabolites. Together with myrosinases and supplementary proteins known as specifier proteins, they form the glucosinolate-myrosinase system that upon tissue...
Dibyajyoti Banerjee et al.
Clinica chimica acta; international journal of clinical chemistry, 337(1-2), 147-152 (2003-10-22)
Hydroperoxides are well-recognized reactive oxygen species which are associated with oxidative stress, a phenomenon of current clinical interest as oxidative stress is associated with a number of disease condition. Ferrous ion oxidation xylenol orange (FOX) methods of hydroperoxide estimation has...
Jisen Zhang et al.
The Journal of reproduction and development, 58(6), 678-684 (2012-09-14)
Endothelin (ET)-2 plays a crucial role in ovarian ovulation in mammals. The present study was designed to test the hypothesis that hypoxia-inducible factor (HIF)-1α-mediated transcriptional activation contributes to the increased expression of ET-2 gene in response to hCG in rat...
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