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Shin-Yi Yang et al.
Archives of biochemistry and biophysics, 564, 43-51 (2014-12-03)
The aim of the present study aimed to investigate whether glycated bovine serum albumin (BSA) showed novel activities on the lipid-water interface. Mannosylated BSA (Man-BSA) was prepared by modification of the carboxyl groups with p-aminophenyl α-d-mannopyranoside. In contrast to BSA
Steffen Schreiber et al.
Anticancer research, 34(12), 7045-7053 (2014-12-17)
The WAP-T mouse model is an established clinically relevant model of breast cancer. Lectins have been used to study malignant progression in clinical studies. We investigated lectin binding sites to test for the clinical relevance of this model. Samples of
Rajesh Kumar et al.
Journal of colloid and interface science, 456, 241-245 (2015-07-08)
In this article, 3-mercaptopropyl functionalized silica entrapped polyacrylamide hydrogel (MPFS-PAA) was prepared and characterized by FT-IR, scanning electron microscopy (SEM) and energy dispersion X-ray spectroscopy (EDS). Synthesized hydrogel was evaluated for removal of arsenic(III) from aqueous solution. Adsorption studies were
Tavakol Heidary Shayesteh et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 69, 44-50 (2015-01-01)
In this study, the acid dissociation constants (pKa) of some benzodiazepine derivatives including chlordiazepoxide, clonazepam, lorazepam, and oxazepam in aqueous micellar solution were determined spectrophotometrically at an ionic strength of 0.1M at 25°C. The effect of cetyl trimethylammonium bromide (CTAB)
Eleanor Bott et al.
The American journal of forensic medicine and pathology, 34(1), 23-25 (2013-01-31)
The authors report a case of suicide by hydrogen sulfide in Australia. A young woman was located in a car wearing protective eyewear. A tub of foamy yellow substance and a quantity of hydrochloric acid and lime sulfur were also
M C Buss et al.
Oncogene, 34(9), 1126-1140 (2014-03-19)
Recent studies suggest that medulloblastoma, the most common malignant brain tumor of childhood, is comprised of four disease variants. The WIP1 oncogene is overexpressed in Group 3 and 4 tumors, which contain medulloblastomas with the most aggressive clinical behavior. Our
Jasmin Matuszak et al.
Clinical hemorheology and microcirculation, 61(2), 259-277 (2015-09-28)
Superparamagnetic iron oxide nanoparticles (SPIONs) are versatile and easily functionalized agents with high potential for diagnostic and therapeutic intravascular applications. In this study, we analyzed the responses of endothelial (ECs) and monocytic cells to three different types of SPIONs, in
Shigeru Hasebe et al.
Behavioural pharmacology, 26(7 Spec No), 681-690 (2015-05-02)
We have recently found that isolation-reared mice show hyperactivity during an encounter with an intruder. However, it is not known whether encounter-induced hyperactivity may model some aspects of psychiatric disorders. The present study examined the pharmacological profile of encounter-induced hyperactivity
Irena Roskar et al.
Journal of diabetes investigation, 6(6), 625-631 (2015-11-07)
Acute glucose fluctuations during the postprandial period pose great risk for cardiovascular complications and thus represent an important therapeutic approach in type 2 diabetes. In the present study, screening of peptide libraries was used to select peptides with an affinity towards
B P Antunes et al.
Carbohydrate polymers, 130, 104-112 (2015-06-17)
Frequently, skin is subjected to damaging events, such as deep cuts, burns or ulcers, which may compromise the integrity of this organ. To overcome such lesions, different strategies have been employed. Among them, wound dressings aimed to re-establish skin native
Patrick Neiens et al.
ChemMedChem, 10(11), 1924-1931 (2015-09-04)
MS Binding Assays are a label-free alternative to radioligand binding assays. They provide basically the same capabilities as the latter, but an unlabeled reporter ligand is used instead of a radioligand. The study presented herein describes the development of MS
Yoshiyuki Hattori et al.
International journal of oncology, 47(1), 211-219 (2015-05-09)
Previously, we found that the injection of zoledronic acid (ZOL) into mice bearing tumor induced changes of the vascular structure in the tumor. In this study, we examined whether ZOL treatment could decrease interstitial fluid pressure (IFP) via change of
Brad Hall et al.
Optometry and vision science : official publication of the American Academy of Optometry, 92(7), 781-789 (2015-05-24)
To compare the adsorption of lysozyme, lactoferrin, and albumin to various contact lens materials, between single-protein solutions and a multicomponent artificial tear solution (ATS). Additionally, extra steps were taken to distinguish loosely and tightly bound protein, the latter of which
Yan Cai et al.
BMC pulmonary medicine, 15, 72-72 (2015-07-17)
Secretoglobin (SCGB) 3A2, a cytokine-like secretory protein of small molecular weight, is predominantly expressed in airway epithelial cells. While SCGB3A2 is known to have anti-inflammatory, growth factor, and anti-fibrotic activities, whether SCGB3A2 has any other roles, particularly in lung homeostasis
Qiqi Zhuo et al.
Journal of colloid and interface science, 457, 243-247 (2015-07-22)
Nascent hydrogen as a strong reducing and environmentally benign agent can be used as the efficient reductant of graphene oxide. The common method is to dissolve metal in acid graphene oxide (GO) solution to generate nascent hydrogen and reduce graphene
Toraj Ahmadi-Jouibari et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 32(7), 1140-1147 (2015-05-12)
Human exposure to inorganic arsenic (iAs) via rice consumption is of increasing concern. In the present study, microwave-assisted dispersive liquid-liquid micro-extraction (MADLLME) and electrothermal atomic absorption spectrometry (ETAAS) were developed for the speciation of iAs in rice samples. After microwave-assisted
Benjamin Tillmann Käsdorf et al.
Biophysical journal, 109(10), 2171-2181 (2015-11-21)
The efficient treatment of many ocular diseases depends on the rapid diffusive distribution of solutes such as drugs or drug delivery vehicles through the vitreous humor. However, this multicomponent hydrogel possesses selective permeability properties, which allow for the diffusion of
Negar Sehati et al.
Journal of chromatography. A, 1420, 46-53 (2015-10-20)
In this paper, TiO2 nanowires and TiO2 nanoparticles have been successfully anchored on graphene oxide (GO) nanosheets by a facile one-step hydrothermal method. The synthesized TiO2 NWs/RGO and TiO2 NPs/RGO nanocomposites were characterized by Fourier transform infrared spectroscopy (FTIR), scanning
Bhawana Sachdeva et al.
Journal of food science and technology, 52(9), 6017-6023 (2015-09-08)
The objectives of the study were to evaluate the bioavailability of iron in milk fortified with ferric pyrophosphate (FPP) soluble and vitamin A acetate and to establish the role of vitamin A in enhancement of iron absorption. Balance indices viz.
Daniel S Jones et al.
Applied and environmental microbiology, 81(9), 3142-3156 (2015-03-01)
Large sulfur-oxidizing bacteria in the family Beggiatoaceae are important players in the global sulfur cycle. This group contains members of the well-known genera Beggiatoa, Thioploca, and Thiomargarita but also recently identified and relatively unknown candidate taxa, including "Candidatus Thiopilula" spp.
Nelson K Totah et al.
Psychopharmacology, 232(20), 3697-3707 (2015-07-24)
Shifting to a new rule is a form of behavioral flexibility that is impaired in numerous psychiatric and neurological illnesses. Animal studies have revealed that this form of flexibility depends upon norepinephrine (NE) neurotransmission. Atomoxetine, a NE reuptake inhibitor, improves
Nikhil Bhalla et al.
Biosensors & bioelectronics, 71, 121-128 (2015-04-22)
Protein kinases are cellular switches that mediate phosphorylation of proteins. Abnormal phosphorylation of proteins is associated with lethal diseases such as cancer. In the pharmaceutical industry, protein kinases have become an important class of drug targets. This study reports a
Hanna Trzeciakiewicz et al.
Sensors (Basel, Switzerland), 15(8), 19429-19442 (2015-08-12)
The adsorption of the proteins CD13, mucin and bovine serum albumin on VLGXE-Au and YNGRT-Au interfaces was monitored by electrochemical impedance spectroscopy in the presence of [Fe(CN)6](3-/4-). The hydrophobicity of the Au surface was tailored using specific peptides, blocking agents
Marco Roverso et al.
Metallomics : integrated biometal science, 7(7), 1146-1154 (2015-04-29)
Obtaining the knowledge of the "omics" and therefore of the metallomics of gestational diabetes mellitus (GDM) appears to be a necessary task to obtain information about the molecular causes of this disease. In this study, the metallome of GDM and
Nathan Wolf et al.
Rapid communications in mass spectrometry : RCM, 29(15), 1448-1456 (2015-07-07)
The eco-physiological mechanisms that govern the incorporation and routing of macronutrients from dietary sources into consumer tissues determine the efficacy of stable isotope analysis (SIA) for studying animal foraging ecology. We document how changes in the relative amounts of dietary
Hui-Ning Fan et al.
Molecular medicine reports, 12(3), 3351-3358 (2015-06-03)
The present study aimed to investigate the effects of endogenous hydrogen sulfide (H2S) on the expression levels of angiotensin II type 1 receptor (AGTR1) in a rat model of carbon tetrachloride (CCl4)‑induced hepatic fibrosis. A total of 56 Wistar rats
Elizabeth A Ennis et al.
ACS chemical neuroscience, 6(3), 417-427 (2015-01-07)
The high-affinity choline transporter (CHT) is the rate-limiting determinant of acetylcholine (ACh) synthesis, yet the transporter remains a largely undeveloped target for the detection and manipulation of synaptic cholinergic signaling. To expand CHT pharmacology, we pursued a high-throughput screen for
Miyeoun Song et al.
Cell transplantation, 24(2), 183-190 (2014-01-02)
The long-term effect of magnetically targeted neural stem cells in a rat focal cerebral ischemia model was investigated. In middle cerebral artery occlusion (MCAO) stroke model rats, ferumoxide-labeled human neural stem cells (hNSCs) were injected into the tail vein. MCAO
Nahid Moghbel et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 997, 142-145 (2015-06-27)
A reversed-phase HPLC-UV method was developed, optimized, and validated for the separation and quantitation of six target alkaloids from leaves of Nicotiana species (nicotine, nornicotine, anatabine, anabasine, myosmine, and cotinine). A bidentate reversed-phase C18 column was used as stationary phase
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