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Md Nasar Mallick et al.
BioMed research international, 2015, 513875-513875 (2015-11-12)
Hydroalcoholic extract of Picrorhiza kurroa and its fractions were subjected to in vitro screening for cytotoxicity; further best active fraction (BAF) obtained was tested against Ehrlich ascites carcinoma (EAC) model in Balb/c mice after its quality control analysis. Cytotoxicities of
Irena Roskar et al.
Journal of diabetes investigation, 6(6), 625-631 (2015-11-07)
Acute glucose fluctuations during the postprandial period pose great risk for cardiovascular complications and thus represent an important therapeutic approach in type 2 diabetes. In the present study, screening of peptide libraries was used to select peptides with an affinity towards
Gwenaëlle Sana et al.
Cell transplantation, 23(9), 1127-1142 (2013-04-16)
The success of liver cell therapy remains closely dependent on how well the infused cells can be accepted after transplantation and is directly related to their degree of immunogenicity. In this study, we investigated the in vitro immunogenic properties of
W G Brydon et al.
European journal of gastroenterology & hepatology, 8(2), 117-123 (1996-02-01)
To assess the reliability of serum 7 alpha-hydroxy-4-cholesten-3-one (7 alpha-3ox-C) in the differential diagnosis of bile acid induced diarrhoea by comparison with 75selenohomocholyltaurine whole body retention (SeHCAT WBR). One hundred and sixty-four patients with chronic diarrhoea were investigated prospectively in
Prabhu Thangadurai et al.
Journal of hazardous materials, 246-247, 245-256 (2013-01-15)
The efficiencies of reductive transformation of endosulfan by bimetallic systems consisting of zerovalent magnesium (Mg(0)) as the electron donor and three forms of palladium as the catalyst (Pd(0)-alumina, Pd(0)-carbon and Pd-K(2)PdCl(6)) were compared in this investigation. Results revealed that both
Cinzia La Rocca et al.
International journal of environmental research and public health, 11(10), 10146-10164 (2014-10-01)
Within the PREVIENI project, infertile and fertile women were enrolled from metropolitan, urban and rural Italian areas. Blood/serum levels of several endocrine disrupters (EDs) (perfluorooctane sulfonate, PFOS; perfluorooctanoic acid, PFOA; di-2-ethylhexyl-phthalate, DEHP; mono-(2-ethylhexyl)-phthalate, MEHP; bisphenol A, BPA) were evaluated concurrently
Mohamed M Radwan et al.
Fitoterapia, 99, 341-346 (2014-09-01)
The antifungal activity of twenty-two common spices was evaluated against plant pathogens using direct-bioautography coupled Colletotrichum bioassays. Turmeric, nutmeg, ginger, clove, oregano, cinnamon, anise, fennel, basil, black cumin, and black pepper showed antifungal activity against the plant pathogens Colletotrichum acutatum
Tim Sobolevsky et al.
Drug testing and analysis, 7(2), 131-142 (2014-11-28)
The data are reported for an in vitro metabolism study of two novel synthetic cannabinoids, N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide (APICA) and its fluorinated analog N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide (5F-APICA, STS-135), which are active ingredients of smoking mixtures sold in Russia since 2012. The cannabinoids were isolated
Kevork Hagopian et al.
PloS one, 10(4), e0124204-e0124204 (2015-04-17)
Shc proteins interact with the insulin receptor, indicating a role in regulating glycolysis. To investigate this idea, the activities of key glycolytic regulatory enzymes and metabolites levels were measured in skeletal muscle from mice with low levels of Shc proteins
Antoaneta Pavlova et al.
Journal of chromatographic science, 52(7), 567-572 (2013-07-26)
A study of the analysis of benzene, toluene, ethylbenzene and xylenes by static headspace gas chromatography illustrated the estimation of uncertainty associated with the influence of several parameters, such as preparation of the standard solutions, calibration of the instrument, recovery
Agnieszka Konopacka et al.
eLife, 4 (2015-11-13)
In response to an osmotic challenge, the synthesis of the antidiuretic hormone arginine vasopressin (AVP) increases in the hypothalamus, and this is accompanied by extension of the 3' poly(A) tail of the AVP mRNA, and the up-regulation of the expression
Victoria E González-Rodríguez et al.
Archives of microbiology, 197(2), 117-133 (2014-08-22)
Botrytis cinerea is one of the most relevant plant pathogenic fungi. The first step during its infection process is the germination of the conidia. Here, we report on the first proteome analysis during the germination of B. cinerea conidia, where
Y Wu et al.
Clinical and experimental immunology, 179(2), 277-293 (2014-09-18)
The role of NOD-like receptor family (NLRP3) has been confirmed in various inflammatory diseases. The association between NLRP3 and hyper-bileacidaemia during the sepsis remains unclear. We aimed to investigate whether NLRP3 silencing protects against the sepsis-induced hyper-bileacidaemia. Sepsis was induced
Chun-Ling Chen et al.
Life sciences, 141, 25-31 (2015-09-15)
The effects of preconditioning on cardioprotection have mainly been studied in vitro. No sufficient in vivo experiments have been performed to optimize ischemic preconditioning (IPC) or hypoxic preconditioning (HPC) for clinical applications. The purpose of this study was to establish
A Rossin et al.
Cell death and differentiation, 22(4), 643-653 (2014-10-11)
The death receptor Fas undergoes a variety of post-translational modifications including S-palmitoylation. This protein acylation has been reported essential for an optimal cell death signaling by allowing both a proper Fas localization in cholesterol and sphingolipid-enriched membrane nanodomains, as well
A W Jones et al.
Forensic science international, 37(4), 277-285 (1988-06-01)
Headspace gas chromatography was used to determine the concentration of ethanol and methanol in blood samples from 519 individuals suspected of drinking and driving in Sweden where the legal alcohol limit is 0.50 mg/g in whole blood (11 mmol/l). The
Juan-Juan Ou et al.
Cancer letters, 358(2), 200-209 (2014-12-30)
Lymphangiogenesis critically contributes to the lymphatic metastasis of colorectal carcinomas (CRCs), but the underlying mechanism of CRC lymphangiogenesis remains largely elusive. We have previously demonstrated that Semaphorin-3F (SEMA3F) is critically involved in CRC metastasis, and the receptor of SEMA3F, neuropilin-2
Stefan Vestring et al.
Pflugers Archiv : European journal of physiology, 467(12), 2589-2601 (2015-08-10)
Calcium buffering by mitochondria plays a relevant physiological function in the regulation of Ca(2+) and exocytotic signals in mature chromaffin cells (CCs) from various adult mammals. Whether a similar or different role of mitochondrial Ca(2+) buffering is present in immature
Faiz Ali et al.
Journal of separation science, 37(23), 3426-3434 (2014-09-23)
Ground porous silica monolith particles with an average particle size of 2.34 μm and large pores (363 Å) exhibiting excellent chromatographic performance have been synthesized on a relatively large scale by a sophisticated sol-gel procedure. The particle size distribution was
Sarah Prebihalo et al.
Journal of chromatography. A, 1419, 109-115 (2015-10-08)
An analytical method for identification of emerging contaminants of concern, such as pesticides and organohalogens has been developed and utilized for true discovery-based analysis. In order to achieve the level of sensitivity and selectivity necessary for detecting compounds in complex
Alejandra Nieto et al.
Investigative ophthalmology & visual science, 56(2), 1070-1080 (2015-01-24)
To understand the relationship between rapamycin loading/release and surface chemistries of porous silicon (pSi) to optimize pSi-based intravitreal delivery system. Three types of surface chemical modifications were studied: (1) pSi-COOH, containing 10-carbon aliphatic chains with terminal carboxyl groups grafted via
Guoli Zhao et al.
PLoS genetics, 11(3), e1004984-e1004984 (2015-03-10)
Synaptic connections must be precisely controlled to ensure proper neural circuit formation. In Drosophila melanogaster, bone morphogenetic protein (BMP) promotes growth of the neuromuscular junction (NMJ) by binding and activating the BMP ligand receptors wishful thinking (Wit) and thickveins (Tkv)
Ali Sarafraz-Yazdi et al.
Journal of chromatography. A, 1418, 21-28 (2015-09-29)
In this research, poly (ethylene glycol)-poly (ethylene glycol) grafted flower-like cupric oxidenano particles (PEG-PEG-g-CuO NPs) as a novel fiber coating of solid-phase microextraction (SPME) were synthesized by using sol-gel technology. This fiber was successfully applied to extract and determine the
A R Bird et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 75(11), 538-540 (1989-06-03)
The preparation, regional distribution and standardisation of an acetone-dried extract of human brain thromboplastin was prospectively evaluated. The programme was shown to be easy to implement within the constraints of the World Health Organisation recommendations and offers a practical alternative
Joakim Sandstedt et al.
Cells, tissues, organs, 199(2-3), 103-116 (2014-08-30)
Stage-specific embryonic antigen (SSEA) expression is used to describe the differentiation state of an embryonic stem cell (ESC). In human ESCs, SSEA-3 and SSEA-4 are highly expressed in undifferentiated cells and downregulated upon differentiation. SSEA-4 has also been described as
Mariana Trujillo et al.
Journal of agricultural and food chemistry, 62(42), 10297-10303 (2014-09-30)
A series of nitroderivatives has been synthesized from hydroxytyrosol, the natural olive oil phenol, to increase the assortment of compounds with putative effects against Parkinson's disease. Nitrohydroxytyrosyl esters were obtained from nitrohydroxytyrosol using a chemoselective one-step, high-yield, transesterification procedure. The
E A Tigunova et al.
TSitologiia i genetika, 47(6), 51-71 (2014-01-21)
Butanol--an alternative fuel that on amid dwindling global (accessible) oil reserves can serve as a source of energy. In the industrial-scale butanol is produced by chemical synthesis, although initially butanol production was due to microbiological synthesis. For cost-efficient production, a
María Luz Gómez-Pérez et al.
Journal of chromatography. A, 1389, 133-138 (2015-03-10)
Retrospective analysis has been applied in different samples, including honey, meat, feed and nutraceutical products from ginkgo biloba, soya, royal jelly and green tea, with the aim of searching transformation products of pesticides and veterinary drugs, which were not included
Veronika Ruzsanyi et al.
Journal of breath research, 8(4), 046005-046005 (2014-11-02)
Breath tests allow a non-invasive and fast diagnostic of different specific enzymes' phenotypic functionality. Over the last decade several 13C-breath tests were successfully tested, with the (13)C-urea breath test being approved by the US Food and Drug Administration (FDA) and
J Benz
Journal of human lactation : official journal of International Lactation Consultant Association, 8(1), 27-28 (1992-03-01)
If the dose of insulin and adequate carbohydrate intake is ensured, most diabetic mothers taking insulin will be able to breastfeed satisfactorily. Compared to the dose before pregnancy, the required insulin dose probably will be substantially reduced during breastfeeding. The
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