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Ali Nematollahzadeh et al.
Journal of chromatography. A, 1345, 154-163 (2014-05-03)
In the present work, we report a novel method for the reinforcement of hierarchically structured molecularly imprinted polymer (MIP) for the separation of human serum albumin (HSA) and immunoglobulin G (IgG) proteins under pressure driven flow conditions. The template proteins
Siegfried Wagner et al.
Anticancer research, 35(1), 145-148 (2015-01-01)
Canine prostate cancer (PC) is a highly aggressive malignancy. However, in contrast to man, neither standard screening strategies nor curative therapeutic options exist for the companion animal. A prostate-specific membrane antigen (PSMA) screening as molecular marker akin to human PC
Z Xishan et al.
Cancer gene therapy, 21(9), 397-404 (2014-09-13)
The aim of this study was to investigate the role and mechanism of miR-23a in the regulation of BCR/ABL and to provide a new prognostic biomarker for chronic myeloid leukemia (CML). The expression levels of miR-23a and BCR/ABL were assessed
Angels Ruyra et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 182, 55-63 (2014-12-24)
The zebrafish (Danio rerio) is a widely used model species for biomedical research and is also starting to be a model for aquaculture research. The ZFL cell line, established from zebrafish liver, has been mostly used in toxicological and ecotoxicological
T Simonsson et al.
Nucleic acids research, 26(5), 1167-1172 (1998-04-04)
The c-myc oncogene is one of the most commonly malfunctioning genes in human cancers, and is an attractive target for anti-gene therapy. Although synthetic oligonucleotides designed to silence c-myc expression via one of its major control elements function well in
Saurav Bhattacharya et al.
Biomaterials, 51, 91-107 (2015-03-17)
Thymoquinone (TQ), a major active constituent of black seeds of Nigella sativa, has potential medical applications including spectrum of therapeutic properties against different cancers. However, little is known about their effect on breast cancer cell migration, which is the cause
Israr Ahmad et al.
Molecular and cellular biochemistry, 393(1-2), 209-222 (2014-04-29)
Cytochrome P4502E1 (CYP2E1), glutathione-S-transferase A4-4 (GSTA4-4), and inducible nitric oxide synthase (iNOS) are implicated in maneb- and paraquat-induced toxicity leading to various pathological conditions. The study aimed to investigate the role of CYP2E1 in maneb- and paraquat-induced oxidative stress in
Courtney A Burger et al.
Cell reports, 34(5), 108698-108698 (2021-02-04)
Cone photoreceptors detect light and are responsible for color vision. These cells display a distinct polarized morphology where nuclei are precisely aligned in the apical retina. However, little is known about the mechanisms involved in cone nuclear positioning or the
Wenguang G Liang et al.
Journal of molecular biology, 427(6 Pt B), 1345-1358 (2015-02-01)
CC chemokine ligands (CCLs) are 8- to 14-kDa signaling proteins involved in diverse immune functions. While CCLs share similar tertiary structures, oligomerization produces highly diverse quaternary structures that protect chemokines from proteolytic degradation and modulate their functions. CCL18 is closely
Role of urinary bladder in osmoregulation in marine teleost, Opsanus tau.
D Howe et al.
The American journal of physiology, 235(1), R48-R54 (1978-07-01)
Pavlína Pelcová et al.
Analytica chimica acta, 866, 21-26 (2015-03-04)
A diffusive gradient in thin films technique (DGT) was combined with liquid chromatography (LC) and cold vapor atomic fluorescence spectrometry (CV-AFS) for the simultaneous quantification of four mercury species (Hg(2+), CH3Hg(+), C2H5Hg(+), and C6H5Hg(+)). After diffusion through an agarose diffusive
Dong Kong et al.
The Journal of cell biology, 219(6) (2020-04-10)
Centrioles are precisely built microtubule-based structures that assemble centrosomes and cilia. Aberrations in centriole structure are common in tumors, yet how these aberrations arise is unknown. Analysis of centriole structure is difficult because it requires demanding electron microscopy. Here we
Shivaram Selvam et al.
Colloids and surfaces. B, Biointerfaces, 126, 35-43 (2014-12-30)
Injectable in situ crosslinking hydrogels offer unique advantages over conventional prefabricated hydrogel methodologies. Herein, we synthesize poly(xylitol-co-maleate-co-PEG) (pXMP) macromers and evaluate their performance as injectable cell carriers for tissue engineering applications. The designed pXMP elastomers were non-toxic and water-soluble with
Vijayashankar Suganya et al.
Clinica chimica acta; international journal of clinical chemistry, 450, 210-219 (2015-08-25)
Autism is a complex developmental disability for which no specific diagnostic markers have been identified so far. The present study aimed to evaluate whether there is any abnormal protein(s) excreted in the urine of autistic children by proteome analysis which
Eleonora S Imasheva et al.
The Journal of membrane biology, 239(1-2), 95-104 (2010-11-26)
Salinixanthin, a C(40)-carotenoid acyl glycoside, serves as a light-harvesting antenna in the retinal-based proton pump xanthorhodopsin of Salinibacter ruber. In the crystallographic structure of this protein, the conjugated chain of salinixanthin is located at the protein-lipid boundary and interacts with
Sylvie Mireille Franken et al.
Photodermatology, photoimmunology & photomedicine, 31(2), 83-89 (2014-11-08)
Hospital-based phototherapy is a widely accepted treatment modality in psoriasis patients. It, however, requires several hospital visits weekly, interfering with (school)work. Home ultraviolet (UV) treatment has been proven effective before but is only available in certain countries, and safety aspects
Aurore Masson et al.
Scientific reports, 5, 16898-16898 (2015-11-19)
Today, Light Sheet Fluorescence Microscopy (LSFM) makes it possible to image fluorescent samples through depths of several hundreds of microns. However, LSFM also suffers from scattering, absorption and optical aberrations. Spatial variations in the refractive index inside the samples cause
Hiroko Kita-Matsuo et al.
PloS one, 4(4), e5046-e5046 (2009-04-09)
Developmental, physiological and tissue engineering studies critical to the development of successful myocardial regeneration therapies require new ways to effectively visualize and isolate large numbers of fluorescently labeled, functional cardiomyocytes. Here we describe methods for the clonal expansion of engineered
Anna Labernadie et al.
Nature communications, 5, 5343-5343 (2014-11-12)
Podosomes are adhesion structures formed in monocyte-derived cells. They are F-actin-rich columns perpendicular to the substrate surrounded by a ring of integrins. Here, to measure podosome protrusive forces, we designed an innovative experimental setup named protrusion force microscopy (PFM), which
Claudio D Borsarelli et al.
Free radical biology & medicine, 53(4), 1004-1015 (2012-07-10)
Alpha-synuclein (αS), a 140 amino acid presynaptic protein, is the major component of the fibrillar aggregates (Lewy bodies) observed in dopaminergic neurons of patients affected by Parkinson's disease. It is currently believed that noncovalent oligomeric forms of αS, arising as
Li Zhou et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(7), 2930-2935 (2014-12-17)
Facile growth of CuS nanowires through self-assembly and their application as building blocks for near-infrared light-responsive functional films have been demonstrated. It is found that DNA is a key factor in preparing the CuS material with defined nanostructure. An exclusive
Juliana Ben et al.
Neurochemical research, 39(12), 2492-2500 (2014-10-16)
The epileptogenesis process involves cell signaling events associated with neuroplasticity. The mitogen-activated protein kinases (MAPKs) integrate signals originating from a variety of extracellular stimuli and may regulate cell differentiation, survival, cell death and synaptic plasticity. Here we compared the total
Selective enrichment of zein gene of maize from cereal products using magnetic support having pyrrolidinyl peptide nucleic acid probe.
Khadsai, et al.
Food Chemistry, 338, 127812-127812 (2020)
Beata Krecisz et al.
Contact dermatitis, 64(2), 90-95 (2011-01-08)
High prevalence of occupational dermatoses among hairdressers has been confirmed in many studies, while work-related skin disorders in apprentice hairdressers are less known. The aim of the study was to investigate the frequency of work-related skin disorders among apprentice hairdressers
Junmo Kang et al.
Nanoscale, 7(15), 6567-6573 (2015-03-20)
Recently, carbon materials such as carbon nanotubes and graphene have been proposed as alternatives to indium tin oxide (ITO) for fabricating transparent conducting materials. However, obtaining low sheet resistance and high transmittance of these carbon materials has been challenging due
Soonmin Lim et al.
The Journal of nutritional biochemistry, 25(10), 1058-1065 (2014-07-23)
Ginger (the rhizome of Zingiber officinale Roscoe) has been used worldwide for many centuries in cooking and for treatment of several diseases. The main pharmacological properties of ginger include anti-inflammatory, antihyperglycemic, antiarthritic, antiemetic and neuroprotective actions. Recent studies demonstrated that
Anna Poltronieri et al.
La Medicina del lavoro, 101(6), 403-408 (2010-12-15)
Hairdressers are exposed to irritants and allergenic compounds that may cause contact dermatitis, rhinitis and asthma. In this paper we describe the case of a female, age 33 years, who developed contact dermatitis after 10 years of exposure to ammonium
Zhizhan Gu et al.
Molecular biology of the cell, 25(4), 457-469 (2013-12-18)
Directional mesenchymal cell invasion in vivo is understood to be a stimulated event and to be regulated by cytokines, chemokines, and types of extracellular matrix (ECM). Instead, by focusing on the cellular response to ECM stiffness, we found that soft
Asif Khurshid Qazi et al.
Cancer letters, 359(1), 47-56 (2015-01-03)
Deregulation of PI3K signalling pathway is strongly involved in pathology of cancer and development of resistance in tumour cells. Here, we report that pharmacologically active vasicinone analogue, RLX (7, 8, 9, 10-Tetrahydroazepino [2, 1-b] quinazolin-12-(6H)-on), exhibited potent anticancer activities both
Christian Franck et al.
PloS one, 6(3), e17833-e17833 (2011-04-07)
The interactions between biochemical processes and mechanical signaling play important roles during various cellular processes such as wound healing, embryogenesis, metastasis, and cell migration. While traditional traction force measurements have provided quantitative information about cell matrix interactions in two dimensions
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