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Archana Swami et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(28), 10287-10292 (2014-07-02)
Bone is a favorable microenvironment for tumor growth and a frequent destination for metastatic cancer cells. Targeting cancers within the bone marrow remains a crucial oncologic challenge due to issues of drug availability and microenvironment-induced resistance. Herein, we engineered bone-homing...
Temmei Ito et al.
Biomedical materials (Bristol, England), 10(1), 015025-015025 (2015-03-03)
In order to obtain a hydroxyapatite (HAp)-poly(ethylene glycol) (PEG) composite, tetra amine-terminated PEG was crosslinked using disuccinimidyl tartrate to obtain a PEG hydrogel. Using two kinds of chelators with different stability constants for Ca ion (N-(2-hydroxyethyl) ethylenediamine-N,N',N'-triacetic acid (EDTA-OH, 8.14)...
W S Kwak et al.
Asian-Australasian journal of animal sciences, 28(11), 1592-1598 (2015-11-19)
This study was conducted to determine the effects of feeding a trace minerals-fortified microbial culture (TMC) on the performance and carcass characteristics of late-fattening Hanwoo steers. A mixture of microbes (0.6% [v/w] of Enterobacter sp., Bacillus sp., Lactobacillus sp., and...
The target of metformin in type 2 diabetes.
Ele Ferrannini
The New England journal of medicine, 371(16), 1547-1548 (2014-10-16)
Mathieu Riffault et al.
Pharmaceutical research, 32(12), 3886-3898 (2015-07-03)
Despite the promising applications of PLGA based particles, studies examining the fate and consequences of these particles after intra-articular administration in the joint are scanty. This study was carried out to evaluate the neutrality of the unloaded delivery system on...
Lactic acidosis.
Jeffrey A Kraut et al.
The New England journal of medicine, 372(11), 1078-1079 (2015-03-12)
Joseph O Rich et al.
Bioresource technology, 196, 347-354 (2015-08-11)
Bacterial contaminants can inhibit ethanol production in biofuel fermentations, and even result in stuck fermentations. Contaminants may persist in production facilities by forming recalcitrant biofilms. A two-year longitudinal study was conducted of bacterial contaminants from a Midwestern dry grind corn...
W Tang et al.
Journal of occupational and environmental hygiene, 12(8), 525-537 (2015-04-08)
This study compares the fungal growth ratio on loaded ventilation filters under various temperature, relative humidity (RH), and air flow conditions in a controlled laboratory setting. A new full-size commercial building ventilation filter was loaded with malt extract nutrients and...
Yan Ren et al.
Korean journal for food science of animal resources, 35(5), 683-691 (2016-01-14)
The objective of this study was to identify the coccoidal bacteria present in 188 samples of fermented yaks', mares' and cows' milk products collected from 12 different regions in Mongolia. Furthermore, we evaluated the fermentation properties of ten selected isolates...
Ezgi Erdogan et al.
Bioresource technology, 196, 35-42 (2015-08-01)
In this study, the effect of the temperature and reaction time on hydrothermal carbonization (HTC) of orange pomace was investigated. In addition, a set of anaerobic batch tests were performed to determine the resulting biogas and methane potential of the...
D Novoa-Díaz et al.
Ultrasonics, 54(6), 1575-1580 (2014-05-06)
The progress of malolactic fermentation in red wines has been monitored by using ultrasonic techniques. The evolution of ultrasonic velocity of a tone burst 1MHz longitudinal wave was measured, analyzed and compared to those parameters of oenological interest obtained simultaneously...
Xiyuan Li et al.
Gene, 574(1), 41-47 (2015-07-30)
Succinic semialdehyde dehydrogenase (SSADH) deficiency is a rare autosomal recessive disorder that affects the degradation of γ-aminobutyric acid (GABA). Only a few cases of SSADH deficiency have been documented in mainland China and prenatal diagnosis has not been performed. SSADH...
Viswanadhapalli Suryavathi et al.
Biology of reproduction, 92(5), 129-129 (2015-03-13)
ESP1/SPESP1 is a testis-specific, postmeiotic gene expressed in round spermatids that encodes equatorial segment protein 1, an intra-acrosomal protein found in the acrosomal matrix and on the luminal surface of the inner and outer acrosomal membranes within the equatorial segment...
Yang Wang et al.
International journal of environmental research and public health, 12(8), 9218-9236 (2015-08-12)
LDH-C4 is a lactate dehydrogenase that catalyzes the conversion of pyruvate to lactate. In mammals, ldh-c was originally thought to be expressed only in testis and spermatozoa. Plateau pika (Ochotona curzoniae), which belongs to the genus Ochotona of the Ochotonidea...
Tomoko Ariga et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 985, 48-53 (2015-02-07)
Iron (Fe) is an essential element for higher plants, which take it up from the soil at the root surface and transport it to shoots through the xylem. Fe(III) chelators, such as organic acids and phytosiderophores, play important roles in...
Azad Behnan Sabow et al.
Animal science journal = Nihon chikusan Gakkaiho, 86(12), 981-991 (2015-07-25)
This study assessed the effect of halal slaughter and anesthesia pre-slaughter followed by bleeding on meat quality characteristics of goats. Eleven male Boer cross goats were divided into two groups and subjected to either halal slaughter (HS) or anesthesia with...
Federica Balestra et al.
Food chemistry, 187, 451-459 (2015-05-16)
Investigations were made in order to evaluate the influence of the flour type, chemical acidification and fermentation on characteristics of doughs obtained with durum wheat and KAMUT® Khorasan flour. Doughs were observed immediately after mixing, 90 and 360 min of...
Pavlina Lyskova et al.
Mycopathologia, 180(5-6), 407-419 (2015-08-21)
Trichophyton bullosum is a zoophilic dermatophyte from the Arthroderma benhamiae complex with a poorly known distribution. In this study, we report a case of dermatophytosis caused by T. bullosum in a 6-year-old male horse who had a skin lesion located...
Laura Moles et al.
Journal of pediatric gastroenterology and nutrition, 60(1), 120-126 (2014-09-11)
The objective of this work was to elucidate the influence of extremely premature birth (gestational age 24-27 weeks) on the microbiological, biochemical, and immunological composition of colostrum and mature milk. A total of 17 colostrum and 34 mature milk samples...
Maria Elisa da Silva Nunes Gomes Miranda et al.
The journal of adhesive dentistry, 16(2), 115-122 (2014-04-01)
This study evaluated the sorption and solubility of self-etching adhesive systems after immersion in distilled water, lactic acid, and propionic acid. Specimens of 2 two-step (P90 System Adhesive [P90], Clearfil SE Bond [CSE]) and 1 single-step (Adper Easy One [AEO])...
Michael Hawkes et al.
The American journal of tropical medicine and hygiene, 90(4), 605-608 (2014-03-05)
Severe malaria is frequently managed without access to laboratory testing. We report on the performance of point-of-care tests used to guide the management of a cohort of 179 children with severe malaria in a resource-limited Ugandan hospital. Correlation coefficients between...
Anas A Al-Nabulsi et al.
Food microbiology, 46, 154-160 (2014-12-06)
Prevalence of antibiotic resistance of Listeria monocytogenes isolated from a variety of foods has increased in many countries. L. monocytogenes has many physiological adaptations that enable survival under a wide range of environmental stresses. The objective of this study was...
Katie C Coate et al.
American journal of physiology. Endocrinology and metabolism, 307(2), E151-E160 (2014-05-29)
In dogs consuming a high-fat and -fructose diet (52 and 17% of total energy, respectively) for 4 wk, hepatic glucose uptake (HGU) in response to hyperinsulinemia, hyperglycemia, and portal glucose delivery is markedly blunted with reduction in glucokinase (GK) protein...
Matthew L Banks et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(9), 2198-2206 (2015-03-07)
Preclinical and human laboratory choice procedures have been invaluable in improving our knowledge of the neurobiological mechanisms of drug reinforcement and in the drug development process for candidate medications to treat drug addiction. However, little is known about the neuropharmacological...
Shaoying Li et al.
The Journal of antibiotics, 68(2), 81-87 (2014-09-11)
The quinolone resistance of 19 lactic acid bacterial strains belonging to the genera Enterococcus and Lactobacillus isolated from the natural fermented koumiss and yoghurt were investigated. The objective of this study was to determine the quinolone resistance levels and to...
Sara Federici et al.
Meat science, 98(4), 575-584 (2014-08-05)
Lactic acid bacteria (LAB) from Ciauscolo salami produced in Marche Region of Central Italy, and LAB strains belonging to our laboratory collection were examined for their capability to survive at low pH and bile, to adhere to Caco-2 cells, and...
Raffaella Di Cagno et al.
Food microbiology, 33(1), 1-10 (2012-11-06)
Lactic acid fermentation represents the easiest and the most suitable way for increasing the daily consumption of fresh-like vegetables and fruits. Literature data are accumulating, and this review aims at describing the main features of the lactic acid bacteria to...
Jan Kabisch et al.
Food microbiology, 53(Pt B), 15-23 (2015-12-19)
A survey of the psychrotolerant yeast microbiota of vacuum-packed beef was conducted between 2010 and 2012. Chilled vacuum-packed beef (n = 50) sampled from 15 different producers was found to have a mean psychrotolerant yeast count of 3.76 log cfu per cm(2)....
Delphine Bon et al.
Transplantation, 97(8), 810-816 (2014-04-01)
Machine perfusion use has been reported to promote graft outcome in case of donation after cardiac death. Our objective was to evaluate the potential for nuclear magnetic resonance (NMR) to predict graft outcome by analyzing perfusates during machine perfusion time....
Gurinder Singh et al.
Expert opinion on drug delivery, 11(5), 647-659 (2014-03-26)
Trans-resveratrol (t-RVT) is a potent antioxidant. The drug suffers enterohepatic recirculation and extensive first-pass metabolism by CYP3A4 in liver, resulting in very low bioavailability (almost zero). The current studies entail a novel formulation approach to develop systematically optimized (OPT) nanoparticles...
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