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270482

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Andrzej Starek et al.
Archives of toxicology, 82(2), 125-136 (2007-09-18)
This study was carried out to compare the hematological effects of 2-methoxyethanol (ME), 2-ethoxyethanol (EE), 2-isopropoxyethanol (IPE), and 2-butoxyethanol (BE) in short-term studies in rats. Male rats were subcutaneously treated with ME or EE at a dosage of 0, 1.25...
Huiping Yang et al.
Cryobiology, 61(2), 211-219 (2010-07-27)
Medaka Oryzias latipes is a well-recognized biomedical fish model because of advantageous features such as small body size, transparency of embryos, and established techniques for gene knockout and modification. The goal of this study was to evaluate two critical factors...
Yoshikazu Taketa et al.
Toxicologic pathology, 39(2), 372-380 (2011-03-23)
Ethylene glycol monomethyl ether (EGME) is a known reproductive toxicant that induces luteal hypertrophy in rat ovaries. In this study, we characterized the histopathological features of corpora lutea (CL) from EGME-treated rats and compared them with normal CL formation and...
Anil K Gorle et al.
Dalton transactions (Cambridge, England : 2003), 43(44), 16713-16725 (2014-10-02)
A series of inert tri- and tetra-nuclear polypyridylruthenium(II) complexes that are linked by the bis[4(4'-methyl-2,2'-bipyridyl)]-1,n-alkane ligand ("bb(n)" for n = 10, 12 and 16) have been synthesised and their potential as antimicrobial agents examined. Due to the modular nature of...
Farzad Foroutan et al.
ACS nano, 9(2), 1868-1877 (2015-01-28)
Ultrasound imaging is a powerful tool in medicine because of the millisecond temporal resolution and submillimeter spatial resolution of acoustic imaging. However, the current generation of acoustic contrast agents is primarily limited to vascular targets due to their large size....
H-Y Chang et al.
Occupational and environmental medicine, 61(8), 697-702 (2004-07-20)
To evaluate the protective effectiveness of gloves from occupational exposure to 2-methoxyethanol (2-ME); and to examine the association of 2-methoxyacetic acid (MAA) in urine and plasma collected simultaneously from low 2-ME exposure and high 2-ME exposure workers in a semiconductor...
Magdalena Regulska et al.
Pharmacological reports : PR, 62(6), 1243-1249 (2011-01-29)
Ethylene glycol ethers (EGEs) are a class of chemicals used extensively in the manufacture of a wide range of domestic and industrial products, which may result in human exposure and toxicity. Hematologic and reproductive toxicity of EGEs are well known...
Emily Hanson Scofield et al.
Reproductive toxicology (Elmsford, N.Y.), 22(4), 718-724 (2006-07-11)
Diethylene glycol monomethyl ether (DEGME), ethylene glycol monomethyl ether (EGME) and their common metabolite, methoxyacetic acid (MAA) have been associated with adverse reproductive effects. The objective of this research is to investigate the effects of DEGME, EGME and MAA on...
Robert A Hartman et al.
Journal of biomechanics, 45(2), 382-385 (2011-11-22)
Intervertebral disc degeneration, a leading cause of low back pain, poses a significant socioeconomic burden with a broad array of costly treatment options. Mechanical loading is important in disease progression and treatment. Connecting mechanics and biology is critical for determining...
Andrzej Starek et al.
Medycyna pracy, 59(2), 179-185 (2008-07-26)
Ethylene glycol alkyl ethers (EGAE), 2-methoxyethanol, 2-ethoxyethanol, 2-isopropoxyethanol, and 2-butoxyethanol, are widely used in a variety of industrial and household products. They are found in a number of paints, varnishes, engine fuels, hydraulic fluids, and also in many household products...
Seung-Min Ahn et al.
Nano letters, 19(6), 3707-3715 (2019-05-24)
The mechanical flexibility of perovskite solar cells as well as high power conversion efficiency is attracting increasing attention. In addition to existing empirical approaches, such as cyclic bending tests, in this study we report the tensile properties of the perovskite...
Randa El-Zein et al.
Archives of environmental & occupational health, 62(3), 161-163 (2008-04-11)
Little is known about the mechanism by which ethylene glycol monomethyl ether (EGME) produces genotoxic effects in humans. The authors found that individuals exposed in utero to EGME showed characteristic dysmorphic features, unexplained mental retardation, and persistent cytogenetic damage. They...
Elizabeth G Tonkin et al.
Toxicology letters, 190(2), 193-201 (2009-08-01)
The glycol ether solvents 2-methoxyethanol (2-ME) and 2-ethoxyethanol (2-EE) produce testicular toxicity characterized by spermatocyte degeneration, while a similar glycol ether, 2-butoxyethanol (2-BE), has no testicular effects. The goal of the current study was to better understand the mechanism of...
Metabolomics and mechanisms: sometimes the fisher catches a big fish.
Glenn H Cantor
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 321-323 (2010-09-25)
Peng Li et al.
Angewandte Chemie (International ed. in English), 54(2), 574-577 (2014-11-15)
Self-assembly of a trigonal building subunit with diaminotriazines (DAT) functional groups leads to a unique rod-packing 3D microporous hydrogen-bonded organic framework (HOF-3). This material shows permanent porosity and demonstrates highly selective separation of C2H2/CO2 at ambient temperature and pressure.
Tetsushi Dodo et al.
The Journal of toxicological sciences, 34 Suppl 1, SP121-SP128 (2009-04-25)
The objective of this study was to determine the optimal period of administration for detection of ovarian toxicity in rat repeated-dose toxicity studies. A well-known ovarian toxicant, ethylene glycol monomethyl ether (EGME), was administered to female rats at dose levels...
Xuanhe Song et al.
Stem cells international, 2015, 926325-926325 (2015-04-09)
Meniscus reconstruction is in great need for orthopedic surgeons. Meniscal fibrochondrocytes transplantation was proposed to regenerate functional meniscus, with limited donor supply. We hypothesized that coculture of synovial mesenchymal stem cells (SSC) with meniscal fibrochondrocytes (me-CH) can support matrix production...
Chandrika Ravindran Preetha et al.
Environmental science & technology, 40(9), 3070-3074 (2006-05-25)
Major quantities of uranium find use as nuclear fuel in nuclear power reactors. In view of the extreme toxicity of uranium and consequent stringent limits fixed by WHO and various national governments, it is essential to remove uranium from nuclear...
Alberto Dessy et al.
Colloids and surfaces. B, Biointerfaces, 87(2), 236-242 (2011-06-17)
Therapeutic properties of Dead Sea Water (DSW) in the treatment of skin diseases such as atopic dermatitis, psoriasis and photo aging UV damaged skin have been well established. DSW is in fact rich in minerals such as calcium, magnesium, sodium...
Jochem Louisse et al.
Toxicology and applied pharmacology, 245(2), 236-243 (2010-03-17)
Embryotoxicity of glycol ethers is caused by their alkoxyacetic acid metabolites, but the mechanism underlying the embryotoxicity of these acid metabolites is so far not known. The present study investigates a possible mechanism underlying the embryotoxicity of glycol ether alkoxyacetic...
Ronald L Grimm et al.
The journal of physical chemistry. A, 114(3), 1411-1419 (2009-10-24)
We investigate the Rayleigh discharge and evaporation dynamics of highly charged two-component droplets consisting principally of methanol with 2-methoxyethanol, tert-butanol, or m-nitrobenzyl alcohol. A phase Doppler anemometer (PDA) characterizes droplets generated by electrospray ionization (ESI) according to size, velocity, and...
Anna Maria Piras et al.
International journal of pharmaceutics, 357(1-2), 260-271 (2008-03-04)
The preparation of novel biocompatible polymeric nanoconstructs suitable to load sensitive bioactive protein agents is reported. Nanoparticles were prepared as based on hybrid polymeric matrices consisting of synthetic bioerodible alternating copolymers of maleic anhydride and n-butylvinylether hemiesterified with 2-methoxyethanol and...
Shu-Ichi Nakano et al.
FEBS open bio, 4, 643-650 (2014-08-28)
Nucleic acids are useful for biomedical targeting and sensing applications in which the molecular environment is different from that of a dilute aqueous solution. In this study, the influence of various types of mixed solutions of water and water-soluble organic...
Makoto Takei et al.
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 643-652 (2010-07-10)
Ethylene glycol monomethyl ether (EGME) is a widely used industrial solvent known to cause adverse effects to human and other mammals. Organs with high metabolism and rapid cell division, such as testes, are especially sensitive to its actions. In order...
Tamio Fukushima et al.
The Journal of toxicological sciences, 30(3), 195-206 (2005-09-06)
Predictive biomarkers of testicular toxicity are needed for an efficient development of drugs. The purpose of the present study was to obtain further insight into the toxicity mechanisms of various male reproductive toxicants and to detect genomic biomarkers for rapid...
John M Rogers et al.
Birth defects research. Part B, Developmental and reproductive toxicology, 71(1), 17-25 (2004-03-03)
Supernumerary ribs (SNR) of differing sizes are commonly observed in rodent developmental toxicity studies, and the significance of treatment-related increases in SNR in standard studies has been contentious. We induced dose-related increases in SNR in fetal CD-1 mice by treating...
Conductometric, viscometric, and spectroscopic investigations on the solvation phenomena of alkali-metal ions and ion pairs in 2-methoxyethanol.
Das B and Hazra DK.
The Journal of Physical Chemistry, 99(1), 269-273 (1995)
Nicolas Ferrando et al.
The journal of physical chemistry. B, 115(36), 10654-10664 (2011-08-02)
We propose a new transferable force field to simulate phase equilibrium and interfacial properties of systems involving ethers and glycol ethers. On the basis of the anisotropic united-atom force field, only one new group is introduced: the ether oxygen atom....
Alberto Dessy et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 43(1-2), 57-64 (2011-03-30)
In the present work polymeric nanoparticles based on Poly (maleic anhydride-alt-butyl vinyl ether) 5% grafted with m-PEG (2000) and 95% grafted with 2-methoxyethanol (VAM41-PEG) were loaded with human hemoglobin (Hb) and characterized from a physicochemical point of view. The assessment...
A V Nikolenko et al.
Cryo letters, 34(5), 527-534 (2014-01-23)
Oxyethyl derivatives of polyol class members such as glycerol and ethylene glycol with various polymerization degrees possess low toxicity and cryoprotective properties via an exocellular mechanism. To develop the cryoprotective media based on non-penetrating cryoprotectants, we studied cryoprotective and physico-chemical...
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