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forkhead box P1
12CC4, QRF1, hFKH1B
Human FOXP1 (27086), Mouse Foxp1 (108655), Rat Foxp1 (297480), chicken FOXP1 (416092), cow FOXP1 (515903), Horse FOXP1 (100053199), domestic cat FOXP1 (101092171), dog FOXP1 (484692), domestic guinea pig Foxp1 (100733147), naked mole-rat Foxp1 (101722100), sheep FOXP1 (101114648), Domestic Rabbit FOXP1 (100345241)
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008