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30501

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R Ramanathan et al.
Meat science, 93(4), 888-892 (2013-01-15)
Two experiments were conducted to assess the effects of succinate and pH on cooked beef color. In experiment 1, ten strip loins (M. longissimus lumborum) were divided in half and assigned to either non-enhanced control or 2.5% succinate. Each half-loin
Shinji Yamashita et al.
Lipids, 49(12), 1261-1273 (2014-11-12)
We have developed a new method for determining ethanolamine plasmalogen contents in marine invertebrates. This quantification method involves derivatization of ethanolamine glycerophospholipid (EtnGpl) subclasses, alkenylacyl (plasmalogen), diacyl, and alkylacyl subclasses, by enzyme treatment and acetylation, followed by separation and detection
Volodymyr Pauk et al.
Journal of chromatography. A, 1423, 169-176 (2015-11-21)
The chromatographic behaviour of eleven synthetic cathinones and four phenylethylamines under supercritical/subcritical fluid conditions was investigated. Four stationary phases with sub-2μm particles (Waters Acquity UPC(2) BEH silica, BEH 2-ethylpyridine, CSH Fluoro-Phenyl, and HSS C18SB) were evaluated in terms of isomer
Rong Zhang et al.
Journal of chromatography. A, 1362, 168-179 (2014-08-28)
It has been reported that HILIC column chemistry has a great effect on the number of detected metabolites in LC-HRMS-based untargeted metabolite profiling studies. However, no systematic investigation has been carried out with regard to the optimisation of mobile phase
Zheng Wang et al.
Analytica chimica acta, 725, 81-86 (2012-04-17)
A modified SBA-15 mesoporous silica material NH(2)-SBA-15 was synthesized successfully by grafting γ-aminopropyl-triethoxysilane. The material was characterized using transmission electron microscopy (TEM) and Fourier transform infrared/Raman (FT-IR/Raman) spectroscopy, and used for the first time in a flow injection on-line solid
Fida El-Ayoubi et al.
Thrombosis and haemostasis, 113(1), 143-153 (2014-09-26)
Antiserum from rabbits immunised with pure human fibrinogen was affinity purified on immobilised fibrin fragment E (FFE). This FFE antibody (Ab) induced significant growth inhibition of a human cancer xenograft in mice and suppression of tumour angiogenesis, leaving no formed
Alexandr N Simonov et al.
PloS one, 10(11), e0141252-e0141252 (2015-11-21)
Cytochrome P450c17 (P450 17A1, CYP17A1) is a critical enzyme in the synthesis of androgens and is now a target enzyme for the treatment of prostate cancer. Cytochrome P450c17 can exhibit either one or two physiological enzymatic activities differentially regulated by
Shiau Hui Diong et al.
Journal of analytical toxicology, 38(9), 660-666 (2014-08-12)
Gas chromatography-mass spectrometry quantitative method was developed to monitor concentrations of methadone and its metabolite 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) in plasma and urine of patients. The developed method was simple, accurate and reproducible to quantify methadone and EDDP in plasma and urine
Pengfei Jin et al.
Journal of pharmaceutical and biomedical analysis, 70, 151-157 (2012-07-13)
A simple, isocratic, and stability-indicating high-performance liquid chromatography (HPLC) method has been developed for the rapid determination of thiamine (VB(1)), niacinamide (VB(3)), pyridoxine (VB(6)), ascorbic acid (VC), pantothenic acid (VB(5)), riboflavin (VB(2)) and folic acid (VB(9)) in Vitamins with Minerals
Weihong Xu et al.
Applied and environmental microbiology, 80(14), 4153-4161 (2014-05-06)
The vast majority of microscopic life on earth consists of microbes that do not grow in laboratory culture. To profile the microbial diversity in environmental and clinical samples, we have devised and employed molecular probe technology, which detects and identifies
Wyatt A Thornley et al.
Angewandte Chemie (International ed. in English), 54(7), 2068-2072 (2014-12-30)
UV photolysis of the nitridoosmate(VIII) anion, OsO3 N(-) , in low-temperature frozen matrices results in nitrogen-oxygen bond formation to give the Os(II) nitrosyl complex OsO2 (NO)(-) . Photolysis of the Os(II) nitrosyl product with visible wavelengths results in reversion to
Csilla Páger et al.
Electrophoresis, 33(22), 3269-3275 (2012-10-23)
CIEF of components following sequential injection of ampholytes and the sample zone offers unique advantages for analysis. The most important one of these is the efficient separation of amphoteric compounds having pIs outside the pH range of the ampholytes applied
Mir Mahdi Abolghasemi et al.
Journal of chromatography. A, 1381, 48-53 (2015-01-27)
In the present study, 12-tungstophosphoric (PW) acid as heteropoly acid, supported on silica-coated γ-Fe2O3 nanoparticles (NPs), was used as a new fiber coating for solid-phase microextraction (SPME). The γ-Fe2O3@SiO2-PW nanocomposite with high surface area was synthesized and characterized by SEM
Qi Ge et al.
American journal of physiology. Lung cellular and molecular physiology, 309(10), L1093-L1102 (2015-09-06)
Altered ECM protein deposition is a feature in asthmatic airways. Fibronectin (Fn), an ECM protein produced by human bronchial epithelial cells (HBECs), is increased in asthmatic airways. This study investigated the regulation of Fn production in asthmatic or nonasthmatic HBECs
Tiziana Annese et al.
Histochemistry and cell biology, 153(3), 185-192 (2019-12-18)
Diffuse large B-cell lymphomas (DLBCLs) are the most common types of Non-Hodgkin's lymphomas and are highly heterogeneous in terms of phenotype and treatment response. The natural course of DLBCLs tumor progression is featured by a flow of events leading to
Jianshe Wang et al.
Journal of proteome research, 14(1), 330-341 (2014-09-03)
Perfluoroalkyl chemicals (PFASs) are a class of highly stable man-made compounds, and their toxicological impacts are currently of worldwide concern. Administration of perfluorononanoic acid (PFNA), a perfluorocarboxylic acid (PFCA) with a nine carbon backbone, resulted in dose-dependent hepatomegaly in mice
James P Grinias et al.
Journal of chromatography. A, 1370, 270-273 (2014-12-03)
Reducing the particle size distribution (PSD) of sub-2 μm chromatographic packing materials can improve the performance of capillary UHPLC columns, but several size refinement methods are only partially effective in this size range. To this end, a preparative scale hydrodynamic
Chao Yu et al.
Journal of hazardous materials, 283, 519-528 (2014-12-03)
Manganese oxide nanoparticles (MnO NPs) have been regarded as a new class of T1-positive contrast agents. The cytotoxicity of silica coated MnO NPs (MnO@SiO2 NPs) was investigated in human cervical carcinoma cells (HeLa) and mouse fibroblast cells (L929). The changes
Silver electrocrystallization on vitreous carbon from ammonium hydroxide solutions.
Palomar-Pardave M, et al.
Journal of the Electrochemical Society, 143(5), 1551-1558 (1996)
Sandrine Aros-Calt et al.
Journal of proteome research, 14(11), 4863-4875 (2015-10-27)
Staphylococcus aureus can cause a variety of severe disease patterns and can readily acquire antibiotic resistance; however, the mechanisms by which this commensal becomes a pathogen or develops antibiotic resistance are still poorly understood. Here we asked whether metabolomics can
Levi B Wood et al.
Scientific reports, 5, 16622-16622 (2015-11-14)
Alzheimer's disease (AD) therapeutics based on the amyloid hypothesis have shown minimal efficacy in patients, suggesting that the activity of amyloid beta (Aβ) represents only one aspect of AD pathogenesis. Since neuroinflammation is thought to play an important role in
Christoph Hutzler et al.
Archives of toxicology, 88(7), 1295-1308 (2014-06-25)
Electronic (e-)cigarettes have emerged in recent years as putative alternative to conventional tobacco cigarettes. These products do not contain typical carcinogens that are present in tobacco smoke, due to the lack of combustion. However, besides nicotine, hazards can also arise
Chang-Ching Chan et al.
Rapid communications in mass spectrometry : RCM, 26(12), 1507-1514 (2012-05-18)
A method has been developed to reduce the mass spectrometric ion signal suppression associated with the use of TFA as an additive in LC mobile phases. Through post-column infusion of diluted NH(4)OH solution to LC eluents, the ammonium ion introduced
Allison Faig et al.
Langmuir : the ACS journal of surfaces and colloids, 31(43), 11875-11885 (2015-10-22)
Cationic amphiphiles have received increasing attention as antimicrobials given their unique ability to disrupt bacteria cell membranes. While extensive research has demonstrated that amphiphiles' hydrophobic-to-charge ratio significantly modulates antibacterial activity, less work has focused on elucidating the specific impact of
Nicholas A Burd et al.
Journal of applied physiology (Bethesda, Md. : 1985), 117(11), 1363-1370 (2014-10-04)
We aimed to determine the impact of precursor pool dilution on the assessment of postprandial myofibrillar protein synthesis rates (MPS). A Holstein dairy cow was infused with large amounts of L-[1-(13)C]phenylalanine and L-[1-(13)C]leucine, and the milk was collected and fractionated.
Erin Gemperline et al.
Analytical methods : advancing methods and applications, 6(16), 6389-6396 (2015-02-11)
(RS)-3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP) is a competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and is routinely used with rodent models to investigate the role of NMDA receptors in brain function. This highly polar compound is difficult to separate from biological matrices.
Christiane Auray-Blais et al.
Clinica chimica acta; international journal of clinical chemistry, 436, 249-255 (2014-06-10)
Creatine synthesis and transport disorders, Triple H syndrome and ornithine transcarbamylase deficiency are treatable inborn errors of metabolism. Early screening of patients was found to be beneficial. Mass spectrometry analysis of specific urinary biomarkers might lead to early detection and
Shuang Yang et al.
Journal of pharmaceutical and biomedical analysis, 109, 177-183 (2015-03-18)
Fagomine, 1-deoxynojirimycin (DNJ) and 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) are the major bioactive constituents in the active fraction of alkaloids from the traditional Chinese medicine mulberry twig (Ramulus Mori, Chinese name Sang Zhi), which has a strong activity on α-glucosidase in vitro and
Matthew N Newmeyer et al.
Journal of chromatography. A, 1358, 68-74 (2014-07-30)
Methamphetamine is a widely abused psychostimulant containing a chiral center. Consumption of over-the-counter and prescription medications may yield positive amphetamines results, but chiral separation of l- and d-methamphetamine and its metabolite amphetamine can help determine whether the source was licit
Yi Hong et al.
Colloids and surfaces. B, Biointerfaces, 123, 68-74 (2014-09-13)
In this study, we investigated the differences between amorphous and anatase TiO2 at the biomolecular level which could explain differences in the osteoblast response on these surfaces. The number of surface hydroxyl groups in the TiOHT form on amorphous and
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