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339350

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A N Devi et al.
Andrology, 3(4), 685-693 (2015-07-23)
NPHP1, the gene that encodes the protein nephrocystin-1 has been identified to be mutated in Juvenile Nephronophthisis, an autosomal recessive cystic kidney disorder which is the most frequent genetic cause of end-stage renal disease (ESRD) in children and young adults....
Kelly Mayse et al.
Science & justice : journal of the Forensic Science Society, 59(3), 349-358 (2019-05-06)
A study into the modification of 1,8-diazafluoren-9-one (DFO) formulations by the additions of metal salts into the working solution is reported. Similar additions have been found to increase the fluorescence of marks developed using other amino acid reagents including 1,2-indandione...
Ritu Tyagi et al.
Journal of applied toxicology : JAT, 33(2), 134-141 (2011-09-20)
Heavy metals are known for their associated nephrotoxicity and nickel is no exception. An integrated metabonomic approach, based on high-resolution (1) H NMR spectroscopy, was applied to determine the acute biochemical effects of NiCl(2) on the renal tissues of rats....
Sanki Asakawa et al.
PloS one, 10(3), e0119428-e0119428 (2015-03-06)
Nickel (Ni) ions easily elute from many alloys and elicit inflammation and allergies. Previous studies have shown that infections due to the implantation of medical devices cause inflammation and enhance the elution of Ni ions (Ni²⁺). However, cross-talk between infection-...
Zuzana Majercikova et al.
Brain research bulletin, 108, 60-66 (2014-08-31)
Asenapine (ASE) is a novel atypical antipsychotic drug approved for the treatment of schizophrenia and bipolar disorder. Stress is an inseparable part of the human life, which may interfere with the therapeutic effect of different drugs. The aim of the...
Antje Stahl et al.
Antonie van Leeuwenhoek, 108(3), 649-658 (2015-07-01)
Several members of the ubiquitously found γ-proteobacterial genus Marinobacter were described or assumed to inhabit marine environments naturally enriched in heavy metals. However, direct studies that describe the ability of this genus to occupy such environments have not been conducted....
Benny Chain et al.
PloS one, 10(6), e0128381-e0128381 (2015-06-02)
The CCR5 receptor plays a role in several key physiological and pathological processes and is an important therapeutic target. Inhibition of the CCR5 axis by passive or active immunisation offers one very selective strategy for intervention. In this study we...
Shohei Segawa et al.
Metallomics : integrated biometal science, 7(7), 1067-1077 (2015-04-30)
To elucidate the regulatory mechanism for extracellular zinc in the CNS, we examined the zinc uptake characteristics in mouse astrocytes and microglia. Zinc was taken up into the two cell types time-dependently, and the cell-to-medium concentration (C/M) ratio in the...
Alexandra Veyrac et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(19), 7575-7586 (2015-05-15)
In search for the mechanisms underlying complex forms of human memory, such as episodic recollection, a primary challenge is to develop adequate animal models amenable to neurobiological investigation. Here, we proposed a novel framework and paradigm that provides means to...
Zongtang Liu et al.
Journal of hazardous materials, 298, 328-337 (2015-06-22)
To enhance the removal efficiency of 2,2',4,4'-tetrabromodiphenylether (BDE47) in aqueous solutions, novel attapulgite-supported Fe/Ni bimetallic nanoparticles (A-Fe/Ni), which were characterized by a core-shell nanoparticle structure and with an average diameter of 20-40 nm, were synthesized for use in BDE47 degradation....
Jia-Hui Lin et al.
Physical chemistry chemical physics : PCCP, 17(23), 15124-15130 (2015-03-31)
This study describes the synthesis of fluorescent polydopamine dots (PDs) through hydroxyl radical-induced degradation of polydopamine nanoparticles. The decomposition of polydopamine nanoparticles to fluorescent PDs was confirmed using transmission electron microscopy and dark-field microscopy. The analysis of PDs by using...
David A Tovar et al.
PloS one, 10(12), e0143172-e0143172 (2015-12-02)
A novel phantom for image quality testing for functional magnetic resonance imaging (fMRI) scans is described. The cylindrical, rotatable, ~4.5L phantom, with eight wedge-shaped compartments, is used to simulate rest and activated states. The compartments contain NiCl2 doped agar gel...
Katherine R Brimblecombe et al.
ACS chemical neuroscience, 6(1), 124-129 (2014-12-02)
Neuronal T-type voltage-gated Ca(2+) channels are reported to have physiological roles that include regulation of burst firing, Ca(2+) oscillations, and neurotransmitter release. These roles are often exposed experimentally by blocking T-type channels with micromolar Ni(2+). We used Ni(2+) to explore...
Terran E Bergdale et al.
Journal of biotechnology, 161(3), 181-189 (2012-07-14)
Microbiologically induced calcium carbonate precipitation (MICCP) is a naturally occurring biological process that has shown its potential in remediation of a wide range of structural damages including concrete cracks. In this study, genetically engineered microorganisms, capable of producing extracellular polymeric...
Patrick J Kirby et al.
Experimental lung research, 35(10), 858-882 (2009-12-10)
The mechanism(s) by which chronic inhalation of indium phosphide (InP) particles causes pleural fibrosis is not known. Few studies of InP pleural toxicity have been conducted because of the challenges in conducting particulate inhalation exposures, and because the pleural lesions...
Zahra Sharifalhoseini et al.
Journal of colloid and interface science, 455, 110-116 (2015-06-10)
The pure phase of the ZnO nanoparticles (NPs) as anticorrosive pigments was synthesized by the sonication method. The surfaces of the sono-synthesized nanoparticles were covered with the protective silica layer. The durability of the coated and uncoated ZnO NPs in...
Minna Li et al.
Dalton transactions (Cambridge, England : 2003), 44(31), 14071-14076 (2015-07-15)
Hypochlorite has been widely and essentially used as the disinfecting agent of water in our daily life. Rapidly, specifically, quantitatively and simply monitoring ClO(-) in water remains to be investigated and is of importance. For this purpose a novel complex...
Steven J Ryan et al.
PloS one, 7(4), e35320-e35320 (2012-05-09)
The basolateral complex of the amygdala (BLA) is a critical component of the neural circuit regulating fear learning. During fear learning and recall, the amygdala and other brain regions, including the hippocampus and prefrontal cortex, exhibit phase-locked oscillations in the...
Jürgen Berg et al.
Stem cell reviews, 11(1), 133-149 (2014-08-15)
Adult human adipose-derived mesenchymal stem cells (MSC) have been reported to induce neuroprotective effects in models for Parkinson's disease (PD). However, these effects strongly depend on the most optimal application of the transplant. In the present study we compared monolayer-cultured...
Ignacio I Fuentes et al.
Aquatic toxicology (Amsterdam, Netherlands), 155, 142-150 (2014-07-16)
An experiment was designed to assess the capacity of Salvinia minima Baker to uptake and accumulate nickel in its tissues and to evaluate whether or not this uptake can affect its physiology. Our results suggest that S. minima plants are...
Ying Zhang et al.
Molecular medicine reports, 12(3), 3273-3278 (2015-06-06)
The aim of the present study was to explore the toxic effects and underlying mechanisms of nickel ions during therapeutic nickel‑based alloy‑treatment in congenital heart disease by investigating the metal‑induced cytotoxicity to the human monocyte‑derived macrophage cell line THP‑1. THP‑1...
Alexandra Tsybizova et al.
The journal of physical chemistry. A, 117(6), 1171-1180 (2012-08-16)
Electrospray ionization of dilute solutions of phenylpyridines (phpy) in the presence of nickel(II) chloride leads to gaseous ions of the type [Ni(phpy)(m)](2+) with m = 3-5 and [NiCl(phpy)(n)](+) with n = 1-3, which are characterized by various gas-phase experiments in...
Qinggang Wang et al.
Journal of pharmaceutical and biomedical analysis, 111, 288-296 (2015-04-29)
Drug degradation that occurs in HPLC analysis, during either sample preparation or chromatographic separation, can greatly impact method robustness and result accuracy. In this work, we report a case study of drug dimerization in HPLC analysis where proximate causes were...
Jang Ho Joo et al.
Physical chemistry chemical physics : PCCP, 17(45), 30292-30299 (2015-10-27)
Despite the critical functions of divalent metal ions (M(2+)s) in association with duplex DNA, fundamental and general interactions of M(2+)s with spherical nucleic acids (SNAs) composed of single-stranded DNA have rarely been investigated. We have explored that the coordinative nature...
Maria D Pavlaki et al.
Ecotoxicology and environmental safety, 109, 48-55 (2014-08-29)
In aquatic ecosystems several stressors may act together and affect the life traits of organisms. Pesticide runoffs are usually associated with high inputs of organic matter and depletion of oxygen in aquatic systems. This study aimed at combining anthropogenic stress...
Adam F Nugraha et al.
Polymers, 12(7) (2020-07-24)
Several methods to synthesize poly(phenylene) block copolymers through the nickel coupling reaction were attempted to reduce the use of expensive nickel catalysts in polymerization. The model reaction for poly(phenylene) having different types of dichlorobenzene derivative monomers illustrated the potential use...
S Nakanishi et al.
British journal of biomedical science, 70(1), 15-21 (2013-04-27)
A recombinant molecule of the full-length urease gene operon was constructed in vitro from the Japanese urease-positive thermophilic Campylobacter (UPTC) CF89-12 isolate and expressed in Escherichia coli cells. Several large deletion recombinant variants of urease subunit genes were also constructed...
Bangyuan Wu et al.
Ecotoxicology and environmental safety, 109, 70-76 (2014-08-29)
This study was designed to evaluate the toxicological effect of dietary nickel chloride (NiCl2) on the counts of intestinal bacteria and diversity of microorganisms in broilers. Plate counting and polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) assays were used. A...
Yifan Chen et al.
Nature communications, 11(1), 5334-5334 (2020-10-23)
Current techniques of patterned material deposition require separate steps for patterning and material deposition. The complexity and harsh working conditions post serious limitations for fabrication. Here, we introduce a single-step and easy-to-adapt method that can deposit materials in-situ. Its methodology...
Sandesh S Raut et al.
Chemosphere, 250, 126298-126298 (2020-04-03)
Chlorophenol (CP) is considered as environmentally hazardous material due to its acute toxicity, persistent nature and strong bioaccumulation. The dechlorination of 4-CP was investigated by using various catalysts such as bimetallic (Fe0/Cu0, Al0/Fe0), Pd/C, Raney Ni and Fe0 at room...
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