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Xi Zhan et al.
Pharmaceutical research, 32(7), 2280-2291 (2015-01-17)
A key step of delivering extracellular agents to its intracellular target is to escape from endosomal/lysosomal compartments, while minimizing the release of digestive enzymes that may compromise cellular functions. In this study, we examined the intracellular distribution of both fluorecent
Yu-Syuan Luo et al.
Toxicology, 409, 33-43 (2018-07-28)
Trichloroethylene (TCE) and tetrachloroethylene (PCE) are structurally similar chemicals that are metabolized through oxidation and glutathione conjugation pathways. Both chemicals have been shown to elicit liver and kidney toxicity in rodents and humans; however, TCE has been studied much more
Biraja C Dash et al.
Biomaterials, 65, 126-139 (2015-07-08)
Critical limb ischemia is a major clinical problem. Despite rigorous treatment regimes, there has been only modest success in reducing the rate of amputations in affected patients. Reduced level of blood flow and enhanced inflammation are the two major pathophysiological
Da-Young Yeom et al.
Scientific reports, 5, 9817-9817 (2015-05-06)
For the utilization of graphene in various energy storage and conversion applications, it must be synthesized in bulk with reliable and controllable electrical properties. Although nitrogen-doped graphene shows a high doping efficiency, its electrical properties can be easily affected by
T L Resende et al.
Journal of dairy science, 98(7), 4785-4799 (2015-05-11)
The objective of this study was to investigate the effect of incremental amounts of ground flaxseed (GFX) on milk yield and concentrations and yields of milk components, milk fatty acids (FA) profile, ruminal metabolism, and nutrient digestibility in dairy cows
Chun Kiang Chua et al.
Small (Weinheim an der Bergstrasse, Germany), 11(11), 1266-1272 (2014-10-22)
Graphite oxide (GiO) and graphene oxide (GeO) possess wide applicability in technological devices. The exact chemical compositions, structures, and properties of these materials remain vague to the graphene community despite being heavily researched. As metastable materials, the properties of GiO
Kyung-Ho Roh et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(13), E1604-E1613 (2015-04-02)
CD4 molecules on the surface of T lymphocytes greatly augment the sensitivity and activation process of these cells, but how it functions is not fully understood. Here we studied the spatial organization of CD4, and its relationship to T-cell antigen
Changyoon Baek et al.
Journal of biomedical nanotechnology, 9(7), 1293-1298 (2013-08-06)
The current medical technology has constantly demanded novel and advanced materials exhibiting the unique physicochemical properties but, at the same time, possessing the intrinsic biocompatibility. Natural biomolecules based on materials such as peptide- (or protein-) or DNA/RNA derivatives have been
Fuchao Xu et al.
Journal of chromatography. A, 1401, 33-41 (2015-05-23)
A multi-residue analytical method was developed for the determination of a range of flame retardants (FRs), including polybrominated diphenyl ethers (PBDEs), emerging halogenated FRs (EFRs) and organophosphate FRs (PFRs), in food matrices. An ultrasonication and vacuum assisted extraction (UVAE), followed
Cristian Gabriel Miranda et al.
Acta tropica, 152, 8-16 (2015-08-15)
Chagas disease is a major unsolved health issue in Latin America and an emerging threat worldwide. New drugs are urgently needed for chemotherapy as those available (benznidazole and nifurtimox) have variable efficacy and elevated toxicity. Efforts are actually oriented to
Kyung-Hwa Baek et al.
Scientific reports, 5, 17642-17642 (2015-12-04)
The ATPase activities of Hsp70 and Hsc70 are known to be responsible for regulation of various biological processes. However, little is known about the roles of Hsp70 and Hsc70 in modulation of immune responses to antigens. In the present study
Shengfei Zhou et al.
Bioresource technology, 193, 288-296 (2015-07-06)
Model compounds and recalcitrant biomass were studied to elucidate the mechanism of ambient-temperature acid pretreatment of cellulosic biomass for bio-ethanol production. Pure cellulose, a pure hemicellulose and alfalfa stems were pretreated with sulfuric acid under ambient temperature with varied acid
Apichai Sawisit et al.
Bioresource technology, 193, 433-441 (2015-07-15)
Escherichia coli KJ122 was engineered to produce succinate from glucose using the wild type GalP for glucose uptake instead of the native phosphotransferase system (ptsI mutation). This strain now ferments 10% xylose poorly. Mutants were selected by serial transfers in
Micha Ben-Naim et al.
ACS applied materials & interfaces, 12(5), 5901-5908 (2020-01-24)
Silicon has shown promise for use as a small band gap (1.1 eV) absorber material in photoelectrochemical (PEC) water splitting. However, the limited stability of silicon in acidic electrolyte requires the use of protection strategies coupled with catalysts. Herein, spin
Yang Zhang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 960, 52-58 (2014-05-03)
A novel TiO2/diatomite composite (TD) was prepared and then characterized by scanning electron microscope (SEM) and Fourier Transform Infrared (FTIR). The results of SEM showed that after modification, the porous surface of diatomite was covered with TiO2. Both diatomite and
Ines van Dooren et al.
Journal of ethnopharmacology, 169, 69-75 (2015-04-12)
Infusions of Herniaria hirsuta L., Herniaria glabra L. and Herniaria fontanesii J.Gay are well known in Moroccon folk medicine for the treatment of biliary dyskinesia, (uro)lithiasis or as a diuretic. Herniariae Herba which can contain H. glabra and H. hirsuta
Roberta Sanna et al.
Journal of colloid and interface science, 457, 298-306 (2015-07-22)
As a contribution to understand the interactions between mineral surfaces and organic molecules, this study reports an accurate characterization of the bis-(2-ethylhexyl) phthalate (DEHP)-Hydrozincite (DEHP-HY), that has been conduced combining the following techniques: FTIR, NMR, XAS spectroscopies and XRD. XRD
Rachel Wallen et al.
Nanoscale research letters, 10(1), 978-978 (2015-06-25)
Vertically aligned single-walled carbon nanotube (VASWCNT) assemblies are generated on cysteamine and 2-mercaptoethanol (2-ME)-functionalized gold surfaces through amide bond formation between carboxylic groups generated at the end of acid-shortened single-walled carbon nanotubes (SWCNTs) and amine groups present on the gold
Utoomporn Surayot et al.
Bioscience, biotechnology, and biochemistry, 79(10), 1644-1653 (2015-05-15)
Sulfated polysaccharides (SP) isolated from freshwater green algae, Spirogyra neglecta (Hassall) Kützing, and fractionated SPs were examined to investigate their molecular characteristics and immunomodulatory activity. The crude and fractionated SPs (F1, F2, and F3) consisted mostly of carbohydrates (68.5-85.3%), uronic
Mario Esparza et al.
FEMS microbiology letters, 362(15), fnv108-fnv108 (2015-07-15)
Autotrophic fixation of carbon dioxide into cellular carbon occurs via several pathways but quantitatively, the Calvin-Benson-Bassham cycle is the most important. CbbR regulates the expression of the cbb genes involved in CO2 fixation via the Calvin-Benson-Bassham cycle in a number
Abdulsamie Hanano et al.
Chemosphere, 135, 418-426 (2014-12-02)
Environmental hydrocarbon contamination has a serious hazard to human health. Alkanes, the major component of hydrocarbons, can be consumed by various species of yeast. We previously identified a new strain SHSY of Saccharomyces cerevisiae with a remarkable ability to utilize
O Gul et al.
Journal of dairy science, 98(3), 1517-1525 (2015-01-15)
The microbiological and chemical characteristics as well as organic and amino acid profiles of kefir samples made from cow and buffalo milks fermented by kefir grains and starter culture were investigated during storage for 21 d at 4°C. After incubation
Nibedita Kasyapi et al.
Carbohydrate polymers, 92(2), 1116-1123 (2013-02-13)
Bionanowhiskers were extracted from jute by acid hydrolysis. At first cellulose microfibrils were formed by alkali treatment. Addition of an acid to the microfibrils triggered the formation of cellulose nanowhiskers. These were characterized by using different techniques viz. Fourier transform
Gabriel B Akanni et al.
Journal of the science of food and agriculture, 95(5), 1094-1102 (2014-11-06)
The cladodes of Opuntia ficus-indica (prickly pear cactus) have a low protein content; for use as a balanced feed, supplementation with other protein sources is therefore desirable. We investigated protein enrichment by cultivation of the yeasts Candida utilis and Kluyveromyces
Océane Eloidin et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 50(10), 1040-1045 (2015-06-30)
This study evaluates the potential for a novel semidecentralized approach that uses coagulant disinfectant products (CDPs) for humanitarian water treatment, by testing two commercially available products (CDP-W and CDP-T). Their performances were evaluated against the relevant water quality treatment objectives
Tetsuya Saita et al.
Biological & pharmaceutical bulletin, 38(11), 1788-1793 (2015-11-03)
The multikinase inhibitor sorafenib has been used in the treatment of hepatocellular carcinoma, renal cell carcinoma, and differentiated thyroid carcinoma. Here we have demonstrated the production of the first specific antibody against sorafenib. Anti-sorafenib serum was obtained by immunizing mice
Yong Wang et al.
Journal of virological methods, 225, 35-40 (2015-09-08)
Peste des petits ruminants (PPR), a highly contagious disease induced by PPR virus (PPRV), affects sheep and goats. PPRV fusion (F) protein is important for the induction of immune responses against PPRV. We constructed a Semliki Forest virus (SFV) replicon-vectored
P Malati et al.
Bioresource technology, 194, 394-398 (2015-07-26)
A membrane-integrated proton exchange membrane fuel cell that enables in situ fermentation of sugar to ethanol, diffusion-driven separation of ethanol, and its catalytic oxidation in a single continuous process is reported. The fuel cell consists of a fermentation chamber coupled
Yanguo Han et al.
Vaccine, 33(6), 777-782 (2015-01-07)
KISS1 gene-encoding kisspeptins are critical for the onset of puberty and control of adult fertility. This study investigated whether KISS1 can be used as a novel target for immunocastration. Human KISS1 was fused with the HBsAg-S gene for constructing an
Boyan K Garvalov et al.
Nature communications, 5, 5577-5577 (2014-11-26)
Tumours exploit their hypoxic microenvironment to induce a more aggressive phenotype, while curtailing the growth-inhibitory effects of hypoxia through mechanisms that are poorly understood. The prolyl hydroxylase PHD3 is regulated by hypoxia and plays an important role in tumour progression.
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