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Agarose-Assisted Micro-Contact Printing for High-Quality Biomolecular Micro-Patterns.
Jang MJ and Nam Y
Macromolecular Bioscience, 15(5), 613-621 (2015)
Gianluca Etienne et al.
Advanced materials (Deerfield Beach, Fla.), 31(27), e1808233-e1808233 (2019-05-14)
Microcapsules are often used as individually dispersed carriers of active ingredients to prolong their shelf life or to protect premature reactions with substances contained in the surrounding. This study goes beyond this application and employs microcapsules as principal building blocks
Krzysztof Langer et al.
Biomicrofluidics, 12(4), 044106-044106 (2018-07-24)
Droplet-based microfluidics, using water-in-oil emulsion droplets as micro-reactors, is becoming a widespread method for performing assays and especially in the cell biology field. Making a simple and highly portable system for creating emulsion droplets would help to continue the popularization
Jina Ko et al.
Advanced biosystems, 4(12), e1900307-e1900307 (2020-12-05)
There is a need for novel analytical techniques to study the composition of single extracellular vesicles (EV). Such techniques are required to improve the understanding of heterogeneous EV populations, to allow identification of unique subpopulations, and to enable earlier and
Dev Gurera et al.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 377(2138), 20180273-20180273 (2019-04-11)
Titanium is an important material having a high tensile strength-to-density ratio and high corrosion resistance. It has found applications in the aerospace, marine, automotive and biomedical industries. In some of the applications, it is important to have it as a
Marjan Biočanin et al.
Lab on a chip, 19(9), 1610-1620 (2019-03-29)
Single-cell RNA-sequencing (scRNA-seq) has revolutionized biomedical research by enabling the in-depth analysis of cell-to-cell heterogeneity of tissues with unprecedented resolution. One of the catalyzing technologies is single cell droplet microfluidics, which has massively increased the overall cell throughput, routinely allowing
Kevin Alessandri et al.
Scientific reports, 7, 42378-42378 (2017-02-12)
While live 3D high resolution microscopy techniques are developing rapidly, their use for biological applications is partially hampered by practical difficulties such as the lack of a versatile sample chamber. Here, we propose the design of a multi-usage observation chamber
Rebecca Soffe et al.
Scientific reports, 9(1), 14420-14420 (2019-10-09)
Artificial surfaces are commonly used in place of leaves in phyllosphere microbiology to study microbial behaviour on plant leaf surfaces. These surfaces enable a reductionist approach to be undertaken, to enable individual environmental factors influencing microorganisms to be studied. Commonly
Raphael F Tiefenauer et al.
Small (Weinheim an der Bergstrasse, Germany), 14(28), e1801187-e1801187 (2018-06-09)
Plasmonically coupled graphene structures have shown great promise for sensing applications. Their complex and cumbersome fabrication, however, has prohibited their widespread application and limited their use to rigid, planar surfaces. Here, a plasmonic sensor based on gold nanowire arrays on
Janneke M Dickhout et al.
Soft matter, 14(26), 5452-5460 (2018-06-19)
Adhesion of emulsified oil droplets to a surface plays an important role in processes such as crossflow membrane filtration, where the oil causes fouling. We present a novel technique, in which we study oil droplets on a model surface in
Pulsatile micromixing using water-head-driven microfluidic oscillators
Li Z and Kim S
Chemical Engineering Journal, 313(1), 1364-1369 (2017)
Luis Eduardo Portillo-Esquivel et al.
Advanced healthcare materials, 9(14), e2000358-e2000358 (2020-06-17)
Tissue engineering holds promise to replace damaged tissues for repair of vital organs in the human body. In cardiac repairs specifically, approaches are developed for intramyocardial delivery of cells and the epicardial delivery of tissue-engineered cardiac patches, providing benefit of
Dev Gurera et al.
Journal of colloid and interface science, 551, 26-38 (2019-05-11)
Desert beetles, desert grass and cacti use different mechanisms to transport the collected water. It is transported to a location where it is consumed or stored. The mechanisms include heterogeneous wettability, grooves, and Laplace pressure gradient due to conical geometry
Lewis E Scott et al.
Integrative biology : quantitative biosciences from nano to macro, 7(11), 1454-1465 (2015-09-29)
Cells respond to mechanical cues from the substrate to which they are attached. These mechanical cues drive cell migration, proliferation, differentiation, and survival. Previous studies have highlighted three specific mechanisms through which substrate stiffness directly alters cell function: increasing stiffness
Myat Noe Hsu et al.
Advanced healthcare materials, 8(4), e1801277-e1801277 (2019-01-24)
Immunoassays are an important tool in various bioanalytical settings, such as clinical diagnostics, biopharmaceutical analysis, environmental monitoring, and food testing. An enzyme-linked immunosorbent assay (ELISA) is usually used to amplify immunoassay signals; however, it requires labor-intensive and time-consuming procedures, which
Chao Ma et al.
Science advances, 6(44) (2020-11-01)
B cell acute lymphoblastic leukemia (B-ALL) blasts hijack the bone marrow (BM) microenvironment to form chemoprotective leukemic BM "niches," facilitating chemoresistance and, ultimately, disease relapse. However, the ability to dissect these evolving, heterogeneous interactions among distinct B-ALL subtypes and their
Seep Arora et al.
Biomaterials, 234, 119747-119747 (2020-01-18)
The effective deployment of arterial (AECs), venous (VECs) and stem cell-derived endothelial cells (PSC-ECs) in clinical applications requires understanding of their distinctive phenotypic and functional characteristics, including their responses to microenvironmental cues. Efforts to mimic the in-vivo vascular basement membrane
Haowen Yang et al.
Analytical and bioanalytical chemistry, 410(27), 7019-7030 (2018-08-30)
A variety of automated sample-in-answer-out systems for in vitro molecular diagnostics have been presented and even commercialized. Although efficient in operation, they are incapable of quantifying targets, since quantitation based on analog analytical methods (via standard curve analysis) is complex
Aniruddh Sarkar et al.
Scientific reports, 6, 23589-23589 (2016-03-31)
Isolation of low abundance proteins or rare cells from complex mixtures, such as blood, is required for many diagnostic, therapeutic and research applications. Current affinity-based protein or cell separation methods use binary 'bind-elute' separations and are inefficient when applied to
Superhydrophobic surfaces fabricated by microstructuring of stainless steel using a femtosecond laser.
Wu B, et al.
Applied Surface Science, 256(1), 61-66 (2009)
Ester Caffarel-Salvador et al.
Science advances, 7(4) (2021-02-02)
Alternative means for drug delivery are needed to facilitate drug adherence and administration. Microneedles (MNs) have been previously investigated transdermally for drug delivery. To date, drug loading into MNs has been limited by drug solubility in the polymeric blend. We
Immobilization of polysaccharides on a fluorinated silicon surface
Wang A, et al.
Colloids and Surfaces. B, Biointerfaces, 47(1), 57-63 (2006)
Jungil Choi et al.
Advanced healthcare materials, 10(4), e2000722-e2000722 (2020-09-30)
Eccrine sweat contains a rich blend of electrolytes, metabolites, proteins, metal ions, and other biomarkers. Changes in the concentrations of these chemical species can indicate alterations in hydration status and they can also reflect health conditions such as cystic fibrosis
Dev Gurera et al.
Journal of colloid and interface science, 577, 530-541 (2020-06-14)
Air bubbles are of interest in various applications. The study of their formation, interaction with underlying surfaces, and their movement is of importance. Bioinspired conical surfaces have been known to exhibit Laplace pressure gradient which facilitates the movement of liquid
Ville Liimatainen et al.
Advanced materials (Deerfield Beach, Fla.), 32(19), e2000497-e2000497 (2020-04-03)
Bioinspired elastomeric fibrillar surfaces have significant potential as reversible dry adhesives, but their adhesion performance is sensitive to the presence of liquids at the contact interface. Like their models in nature, many artificial mimics can effectively repel water, but fail
Matyáš Fendrych et al.
Nature plants, 4(7), 453-459 (2018-06-27)
The phytohormone auxin is the information carrier in a plethora of developmental and physiological processes in plants1. It has been firmly established that canonical, nuclear auxin signalling acts through regulation of gene transcription2. Here, we combined microfluidics, live imaging, genetic
Pranav Shukla et al.
Langmuir : the ACS journal of surfaces and colloids, 36(8), 1871-1877 (2020-02-19)
Hygroscopic materials are widely used as desiccants for applications including food production, packaging, anti-icing, and gas storage. Current techniques for quantifying the hygroscopicity of materials, such as the use of a tandem differential mobility analyzer or a gravimetric vapor sorption
Ruihua Ding et al.
Biomicrofluidics, 11(1), 014114-014114 (2017-03-28)
Active manipulation of droplets is crucial in droplet microfluidics. However, droplet polydispersity decreases the accuracy of active manipulation. We develop a microfluidic "droplet filter" that accurately separates droplets by size. The droplet filter has a sharp size cutoff and is
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