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452890

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Daniel J Modulevsky et al.
PloS one, 9(5), e97835-e97835 (2014-05-21)
There are numerous approaches for producing natural and synthetic 3D scaffolds that support the proliferation of mammalian cells. 3D scaffolds better represent the natural cellular microenvironment and have many potential applications in vitro and in vivo. Here, we demonstrate that
N Cruz et al.
Chemosphere, 135, 304-311 (2015-05-13)
To assess if the geochemical reactivity and human bioaccessibility of silver nanoparticles (AgNPs) in soils can be determined by routine soil tests commonly applied to other metals in soil, colloidal Ag was introduced to five pots containing urban soils (equivalent
Xavier Matabosch et al.
Drug testing and analysis, 7(8), 663-672 (2014-12-30)
Glucocorticosteroids are prohibited in sports when administered by systemic routes and allowed using other administrations for therapeutic reasons. Therefore, markers to distinguish between routes of administration through the analysis of urine samples are needed in anti-doping control. As a first
Jizhi Lin et al.
Nanoscale, 7(32), 13663-13670 (2015-07-28)
We report the controlled synthesis of [Au25(PPh3)10(SR1)5X2](2+) nanorods (H-SR1: alkyl thiol, H-SC2H4Ph and H-S(n-C6H13)) and Au25(SR2)18 nanospheres (H-SR2: aromatic thiol, H-SPh and H-SNap) under the one-phase thiol etching reaction of the polydisperse Aun(PPh3)m parent-particles (core diameter: 1.3 ± 0.4 nm
Xia Xiang et al.
Talanta, 141, 182-187 (2015-05-13)
We have developed a label-free fluorescence sensor for caffeic acid (CA) by the use of CdTe:Zn(2+) quantum dots (CdTe:Zn(2+) QDs) as an output signal. The principle of sensor is based on the fluorescence quenching and binding properties of Fe(2+) toward
Yan Ni Annie Soh et al.
Drug testing and analysis, 6(7-8), 696-704 (2014-02-28)
The evolving nature of new psychoactive substances (NPS) - often referred to as 'legal highs', 'designer drugs' or 'bath salts' - presents an evolving challenge for toxicologists. Apart from the detection and identification of these compounds, further analytical challenges may
M Hashimoto et al.
Journal of dental research, 94(8), 1085-1091 (2015-06-05)
Nanoparticles (NPs) are currently the focus of considerable attention for dental applications; however, their biological effects have not been fully elucidated. The long-term, slow release of matrix metalloproteases (MMPs) digests collagen fibrils within resin-dentin bonds. Therefore, MMP inhibitors can prolong
Ya-Yao Huang et al.
EJNMMI research, 4(1), 71-71 (2015-06-28)
[(18) F]AFM is a potent and promising PET imaging agent for the serotonin transporter. We carried out an acute toxicity study in rats and radiation dosimetry in monkeys before the translation of the tracer to humans. Single- and multiple-dose toxicity studies
Qinghua Cui et al.
Analytica chimica acta, 724, 86-91 (2012-04-10)
Silver nanoclusters (Ag NCs) templated with DNAs have attracted much attention as novel fluorophores because of their convenient emission tunability by the sequence and length of the template DNAs. However, the precise production of Ag NCs in a site-specific manner
Suk Ho Bhang et al.
Biomaterials, 55, 33-43 (2015-05-03)
At high concentrations, manganese (Mn) promotes cellular neurodevelopment but causes toxicity. Here, we report that Mn ion at high concentrations can be delivered to pheochromocytoma 12 (PC12) cells using gold nanoparticles (AuNPs) to enhance cellular neurodevelopment without toxicity. Mn(2+) release
Mengjuan Hua et al.
Analytica chimica acta, 888, 173-181 (2015-09-01)
We herein proposed a simple and effective strategy for preparing graphene quantum dots (GQDs)-based core-satellite hybrid spheres and further explored the feasibility of using such spheres as the ratiometric fluorescence probe for the visual determination of Hg(2+). The red-emitting CdTe
Changping Zheng et al.
Carbohydrate polymers, 130, 113-121 (2015-06-17)
The flowers of Chrysanthemum morifolium were extracted by boiling water, and a water-soluble polysaccharide (CMJA0S2) with a molecular weight of 6.5 kDa was isolated by anion-exchange chromatography on a DEAE-cellulose column and gel permeation chromatography on a Sephacryl S-300 HR
Shigeto Ikemura et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 33(4), 563-571 (2014-11-28)
The purpose of this study was to examine the effect of tenascin-C (TNC) on the repair of full-thickness osteochondral defects of articular cartilage in vivo. We used a gellan-gellan-sulfate sponge (Gellan-GS) to maintain a TNC-rich environment in the cartilage defects.
C Lemaire et al.
Journal of labelled compounds & radiopharmaceuticals, 58(7), 281-290 (2015-05-27)
An efficient, fully automated, enantioselective multi-step synthesis of no-carrier-added (nca) 6-[(18)F]fluoro-L-dopa ([(18)F]FDOPA) and 2-[(18)F]fluoro-L-tyrosine ([(18)F]FTYR) on a GE FASTlab synthesizer in conjunction with an additional high- performance liquid chromatography (HPLC) purification has been developed. A PTC (phase-transfer catalyst) strategy was
Jun Myung Kim et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 15(14), 2917-2921 (2014-07-26)
Direct evidence for the blue luminescence of gold nanoclusters encapsulated inside hydroxyl-terminated polyamidoamine (PAMAM) dendrimers was provided by spectroscopic studies as well as by theoretical calculations. Steady-state and time-resolved spectroscopic studies showed that the luminescence of the gold nanoclusters consisted
Wei Xie et al.
Nature communications, 6, 7570-7570 (2015-07-04)
Noble metals are important photocatalysts due to their ability to convert light into chemical energy. Hot electrons, generated via the non-radiative decay of localized surface plasmons, can be transferred to reactants on the metal surface. Unfortunately, the number of hot
Sylvie Girard et al.
American journal of reproductive immunology (New York, N.Y. : 1989), 72(4), 422-434 (2014-05-29)
Inflammation during pregnancy has devastating consequences for the placenta and fetus. These events are incompletely understood, thereby hampering screening and treatment. The inflammatory profile of villous tissue was studied in pregnancies at high-risk of placental dysfunction and compared to uncomplicated
Nick Frazier et al.
Molecular pharmaceutics, 12(5), 1605-1614 (2015-04-04)
Previously, water-soluble N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers have been used with gold nanorod (GNR) mediated plasmonic photothermal therapy (PPTT) to induce hyperthermia (43 °C for 10 min) and have been shown to improve delivery of hydrophobic drugs to treat cancer. However, it
Ching-Wei Tung et al.
Nature communications, 6, 8106-8106 (2015-09-01)
Electrochemically converting water into oxygen/hydrogen gas is ideal for high-density renewable energy storage in which robust electrocatalysts for efficient oxygen evolution play crucial roles. To date, however, electrocatalysts with long-term stability have remained elusive. Here we report that single-crystal Co3O4
H Zheng et al.
Brain structure & function, 220(5), 3011-3022 (2014-07-12)
The expression of a vesicular glutamate transporter (VGLUT) suffices to assign a glutamatergic phenotype to neurons and other secretory cells. For example, intestinal L cells express VGLUT2 and secrete glutamate along with glucagon-like peptide 1 (GLP1). We hypothesized that GLP1-positive
Qifei Cong et al.
Carbohydrate research, 393, 43-50 (2014-06-03)
COB1B1S2 was isolated from an alkaline extract of Cassia obtusifolia seeds, and purified by anion-exchange and gel permeation chromatography. It contains arabinose, xylose, and glucuronic acid, in the molar ratio of 5:81:14, with an apparent molecular weight estimated to be
Simone Hanna Brütsch et al.
Antioxidants & redox signaling, 22(4), 281-293 (2014-10-15)
Glutathione peroxidases (Gpx) and lipoxygenases (Alox) are functional counterplayers in the metabolism of hydroperoxy lipids that regulate cellular redox homeostasis. Gpx4 is a moonlighting protein that has been implicated not only as an enzyme in anti-oxidative defense, gene expression regulation
Gautam Das et al.
International journal of nanomedicine, 10 Spec Iss, 165-178 (2015-09-09)
In this work, three different spherulitic nanostructures Cu-CuOA, Cu-CuOB, and Cu-CuOC were synthesized in water-in-oil microemulsions by varying the surfactant concentration (30 mM, 40 mM, and 50 mM, respectively). The structural and morphological characteristics of the Cu-CuO nanostructures were investigated
Semira Unal Yeşiller et al.
Analytica chimica acta, 770, 7-17 (2013-03-19)
A laser induced breakdown spectrometry hyphenated with on-line continuous flow hydride generation sample introduction system, HG-LIBS, has been used for the determination of arsenic, antimony, lead and germanium in aqueous environments. Optimum chemical and instrumental parameters governing chemical hydride generation
Dirce L Komura et al.
International journal of biological macromolecules, 70, 354-359 (2014-07-11)
Pleurotus ostreatus var. florida known as Hiratake has a high nutritional value, presents medicinal and nutraceutical properties and it is one of the consumed mushrooms in Brazil. Thus, the aim of this study was to characterize the chemical structure of
Rita Bastos et al.
Carbohydrate polymers, 124, 322-330 (2015-04-04)
The cell wall polysaccharides of brewers spent yeast Saccharomyces pastorianus (BSY) and the inoculum yeast (IY) were studied in order to understand the changes induced by the brewing process. The hot water and alkali extractions performed solubilized mainly mannoproteins, more
Kwon-Chul Noh et al.
The Analyst, 140(24), 8209-8216 (2015-11-12)
A simple and sensitive colorimetric method for the determination of Pb(2+) ions in aqueous samples was developed using 1-(2-mercaptoethyl)-1,3,5-triazinane-2,4,6-trione (MTT) functionalized silver nanoparticles (MTT-AgNPs). The Pb(2+) ion acted as the metal center of the coordination complex, which formed N-Pb(2+)-O coordination
In Hwan Lee et al.
The Analyst, 140(10), 3543-3550 (2015-04-08)
Water-soluble fluorescent silver nanoclusters (NCs) formed on biomolecule ligands have been extensively studied due to their great potential as new biocompatible fluorescent materials for biosensors. As synthetic ligands, proteins in particular can provide unique structures and functions to the assembled
Aitor Sánchez-Ferrero et al.
Biomaterials, 68, 42-53 (2015-08-13)
Bone tissue engineering demands alternatives overcoming the limitations of traditional approaches in the context of a constantly aging global population. In the present study, elastin-like recombinamers hydrogels were produced by means of carbodiimide-catalyzed crosslinking with citric acid, a molecule suggested
Shin-Ae Park et al.
Scientific reports, 5, 13552-13552 (2015-08-28)
Ag is considered to be one of the best candidates for oxygen reduction reaction electrocatalysts in alkaline media for application in various electrochemical energy devices. In this study, we demonstrate that water activation is a key factor in enhancing the
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