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Fengming Zou et al.
ACS applied materials & interfaces, 7(22), 12168-12175 (2015-05-27)
A novel dual-mode immunoassay based on surface-enhanced Raman scattering (SERS) and fluorescence was designed using graphene quantum dot (GQD) labels to detect a tuberculosis (TB) antigen, CFP-10, via a newly developed sensing platform of linearly aligned magnetoplasmonic (MagPlas) nanoparticles (NPs).
Kathryn Geldart et al.
Applied and environmental microbiology, 81(11), 3889-3897 (2015-04-05)
Antibiotic-resistant enterococcal infections are a major concern in hospitals where patients with compromised immunity are readily infected. Enterococcus faecium bacteria are of particular interest as these pathogens account for over 80% of vancomycin-resistant enterococcal infections. Antimicrobial peptides (AMPs) produced at
Sudkate Chaiyo et al.
Analytica chimica acta, 866, 75-83 (2015-03-04)
A novel, highly selective and sensitive paper-based colorimetric sensor for trace determination of copper (Cu(2+)) ions was developed. The measurement is based on the catalytic etching of silver nanoplates (AgNPls) by thiosulfate (S2O3(2-)). Upon the addition of Cu(2+) to the
The slow death of lethal injection.
Owen Dyer
BMJ (Clinical research ed.), 348, g2670-g2670 (2014-05-02)
Gabriela Morachis-Valdez et al.
Environmental science and pollution research international, 22(12), 9159-9172 (2015-01-15)
Madín Reservoir (MR) is located on the Río Tlalnepantla in Mexico. Previous studies seeking to identify pollutants at this site evidence that MR water contains a considerable metal load as well as nonsteroidal anti-inflammatory drugs (NSAIDs) at concentrations above those
Bradley W Davis et al.
Biophysical journal, 109(10), 2182-2194 (2015-11-21)
Subcellular compartmentalization of biomolecules and their reactions is common in biology and provides a general strategy for improving and/or controlling kinetics in metabolic pathways that contain multiple sequential enzymes. Enzymes can be colocalized in multiprotein complexes, on scaffolds or inside
Kazuki Miyaji et al.
Journal of applied animal welfare science : JAAWS, 18(4), 355-362 (2015-02-14)
The objective of this study was to evaluate the effects of diet on the feline stress response by measuring plasma and urinary cortisol. A study diet was developed with a unique combination of nutrients that supports the management of stressful
Whitney Ann Cary et al.
World neurosurgery, 84(5), 1256-1266 (2015-06-16)
The dura mater can be easily biopsied during most cranial neurosurgical operations. We describe a protocol that allows for robust generation of induced pluripotent stem cells (iPSCs) and neural progenitors from acutely harvested dura mater. To generate iPSCs and neural
Ronald F Parsons et al.
Current opinion in organ transplantation, 19(2), 100-107 (2014-02-21)
To update the reader on the recent literature in liver, kidney, pancreas, and intestine static cold preservation, and to identify which solutions are most advantageous for each organ. The comparison of randomized trials of histidine-tryptophan-ketoglutarate (HTK), Celsior, and University of
Matilde Durán-Lobato et al.
Biomacromolecules, 15(7), 2725-2734 (2014-06-24)
Oral drug delivery is a route of choice for vaccine administration because of its noninvasive nature and thus efforts have focused on efficient delivery of vaccine antigens to mucosal sites. An effective oral vaccine delivery system must protect the antigen
Noomi Altgärde et al.
The Journal of biological chemistry, 290(35), 21473-21485 (2015-07-15)
Glycoprotein C (gC) mediates the attachment of HSV-1 to susceptible host cells by interacting with glycosaminoglycans (GAGs) on the cell surface. gC contains a mucin-like region located near the GAG-binding site, which may affect the binding activity. Here, we address
Shu Rui Ng et al.
The Analyst, 140(12), 4224-4231 (2015-04-29)
pH sensors were fabricated by anodically electrodepositing iridium oxide films (AEIROFs) onto microelectrodes on chips and coated with poly(ethyleneimine) (PEI) for mechanical stability. These demonstrate super-Nernstian response to pH from pH 4.0 to 7.7 in chloride-free phosphate buffer. The surface
Paola Ciceri et al.
Molecular and cellular biochemistry, 410(1-2), 197-206 (2015-09-09)
An increasing amount of patients affected by advanced chronic kidney disease suffer from vascular calcification (VC) that associates with cardiovascular morbidity and mortality. In this study, we created a new experimental in vitro model, trying to better elucidate high phosphate
Gabriel E Zentner et al.
Nature communications, 6, 8733-8733 (2015-10-23)
Chromatin endogenous cleavage (ChEC) uses fusion of a protein of interest to micrococcal nuclease (MNase) to target calcium-dependent cleavage to specific genomic loci in vivo. Here we report the combination of ChEC with high-throughput sequencing (ChEC-seq) to map budding yeast
Jingyao Zhang et al.
Shock (Augusta, Ga.), 43(3), 276-284 (2014-11-14)
Zymosan-induced multiple organ dysfunction syndrome (MODS) is a multifactorial pathology that involves the deterioration of function of several organs. 5-Hydroxytryptamine (5-HT) is a small monoamine molecule that is primarily known for its role as a neurotransmitter. Previous studies have shown
Chen Dai et al.
Journal of immunology (Baltimore, Md. : 1950), 194(12), 5980-5989 (2015-05-13)
CXCL14 is a chemokine with an atypical, yet highly conserved, primary structure characterized by a short N terminus and high sequence identity between human and mouse. Although it induces chemotaxis of monocytic cells at high concentrations, its physiological role in
Steve Landsmann et al.
ChemSusChem, 8(20), 3451-3458 (2015-09-12)
Semiconductor powders are perfectly suited for the scalable fabrication of particle-based photoelectrodes, which can be used to split water using the sun as a renewable energy source. This systematic study is focused on variation of the electrode design using LaTiO2
Takashi Watanabe et al.
The Journal of cell biology, 210(5), 737-751 (2015-09-02)
Microtubules (MTs) play critical roles in various cellular events, including cell migration. End-binding proteins (EBs) accumulate at the ends of growing MTs and regulate MT end dynamics by recruiting other plus end-tracking proteins (+TIPs). However, how EBs contribute to MT
Christoph Gerhardt et al.
The Journal of cell biology, 210(1), 115-133 (2015-07-08)
Mutations in RPGRIP1L result in severe human diseases called ciliopathies. To unravel the molecular function of RPGRIP1L, we analyzed Rpgrip1l(-/-) mouse embryos, which display a ciliopathy phenotype and die, at the latest, around birth. In these embryos, cilia-mediated signaling was
M Lorenzetti et al.
Biomedical materials (Bristol, England), 10(4), 045012-045012 (2015-08-01)
This study reports on the selective adsorption of whole plasma proteins on hydrothermally (HT) grown TiO2-anatase coatings and its dependence on the three main surface properties: surface charge, wettability and roughness. The influence of the photo-activation of TiO2 by UV
Lizan Kawa et al.
Journal of neurotrauma, 32(16), 1190-1199 (2014-12-20)
Exposure to improvised explosive devices can result in a unique form of traumatic brain injury--blast-induced traumatic brain injury (bTBI). At the mild end of the spectrum (mild bTBI [mbTBI]), there are cognitive and mood disturbances. Similar symptoms have been observed
Kyu-Sang Kwon et al.
Environmental technology, 34(17-20), 2757-2764 (2014-02-18)
In this study, the deposition and transport of Pseudomonas aeruginosa on sandy porous materials have been investigated under static and dynamic flow conditions. For the static experiments, both equilibrium and kinetic batch tests were performed at a 1:3 and 3:1
Berenice Fernández-Rojas et al.
Molecular and cellular biochemistry, 406(1-2), 183-197 (2015-05-15)
The potential of C-phycocyanin (C-PC) to prevent cisplatin (CP)-induced kidney mitochondrial dysfunction was determined in CD-1 male mice. The CP-induced mitochondrial dysfunction was characterized by ultrastructural abnormalities and by decrease in the following parameters in isolated kidney mitochondria: adenosine diphosphate
A Hynowska et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 103(8), 1569-1579 (2014-12-24)
The microstructure, mechanical behaviour, and biocompatibility (cell culture, morphology, and cell adhesion) of nanostructured Ti45 Zr15 Pd35- x Si5 Nbx with x = 0, 5 (at. %) alloys, synthesized by arc melting and subsequent Cu mould suction casting, in the form of
Xinyi Chia et al.
ACS nano, 9(5), 5164-5179 (2015-04-22)
Layered transition metal dichalcogenides (TMDs) have been the center of attention in the scientific community due to their properties that can be tapped on for applications in electrochemistry and hydrogen evolution reaction (HER) catalysis. We report on the effect of
Mária Lalkovičová et al.
Neurochemical research, 40(8), 1728-1738 (2015-07-29)
Brain damage caused by ischemia or toxic agents leads in selectively vulnerable regions to apoptosis-like delayed neuronal death and can result in irreversible damage. Selectively vulnerable neurons of the CA1 area of hippocampus are particularly sensitive to ischemic damage. We
Brianna L Petrone et al.
Journal of clinical microbiology, 53(9), 2970-2976 (2015-07-17)
Mycoplasma pneumoniae is a leading cause of community-acquired pneumonia (CAP) across patient populations of all ages. We have developed a loop-mediated isothermal amplification (LAMP) assay that enables rapid, low-cost detection of M. pneumoniae from nucleic acid extracts and directly from
Anja Balk et al.
Pharmaceutical research, 32(6), 2154-2167 (2014-12-24)
A poorly water soluble acidic active pharmaceutical ingredient (API) was transformed into an ionic liquid (IL) aiming at faster and higher oral availability in comparison to a prodrug. API preparations were characterized in solid state by single crystal and powder
Masaya Munekage et al.
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 18(4), 387-390 (2015-08-09)
Although the effects on prognosis of blood glucose level variability have gained increasing attention, it is unclear whether blood glucose level variability itself or the manifestation of pathological conditions that worsen prognosis. Then, previous reports have not been published on
A C Mamede et al.
Medical oncology (Northwood, London, England), 32(12), 257-257 (2015-10-29)
Hepatocellular carcinoma (HCC) has a worldwide high incidence and mortality. For this reason, it is essential to invest in new therapies for this type of cancer. Our team already proved that human amniotic membrane (hAM) is able to inhibit the
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