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L Buizza et al.
Cell death & disease, 4, e484-e484 (2013-02-09)
The role of p53 in neurodegenerative diseases is essentially associated with neuronal death. Recently an alternative point of view is emerging, as altered p53 conformation and impaired protein function have been found in fibroblasts and blood cells derived from Alzheimer's
İbrahim Gülseren et al.
Food chemistry, 135(2), 770-774 (2012-08-08)
Whey protein isolate (WPI) nanoparticles were prepared using ethanol desolvation, and their capacity to incorporate ZnCl(2) was analysed. Desolvation was carried out at pH 9 and the volume of added ethanol was 0-3 times the volume of protein solution. The
Hatice Yorulmaz et al.
Biological trace element research, 151(2), 256-262 (2012-11-28)
We evaluated the effect of zinc treatment on the blood-brain barrier (BBB) permeability and the levels of zinc (Zn), natrium (Na), magnesium (Mg), and copper (Cu) in the brain tissue during epileptic seizures. The Wistar albino rats were divided into
Krystyna Poreba et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 21(5), 563-571 (2013-01-30)
Derivatives of isoxazolopyridines exhibit diverse biological activity. One method of synthesizing isoxazolo[4,5-b]pyridines is Friedlander condensation. To establish the conditions necessary for conventional and microwave synthesis of new 3,5,6,7-tetrasubstituted isoxazolo[4,5-b]pyridines and their antiproliferative activity. The substrates in the synthesis of new
Manuella P Kaster et al.
Pharmacological reports : PR, 64(3), 706-713 (2012-07-21)
In this work, the contribution of NMDA receptors to the antidepressant-like effect of adenosine in the forced swimming test (FST) was investigated. The pretreatment of mice with NMDA or D-serine was able to prevent the anti-immobility effect of either adenosine
Hung-Lung Chiang et al.
Environmental science and pollution research international, 20(8), 5781-5789 (2013-03-09)
Pyrolysis enables ZnCl2 immersed biosolid to be reused, but some hazardous air pollutants are emitted during this process. Physical characteristics of biosolid adsorbents were investigated in this work. In addition, the constituents of pyrolytic exhaust were determined to evaluate the
Biyin Cao et al.
The Journal of biological chemistry, 288(47), 34181-34189 (2013-10-12)
The antiparasitic clioquinol (CQ) represents a class of novel anticancer drugs by interfering with proteasome activity. In the present study, we found that CQ induced blood cancer cell apoptosis by inhibiting histone deacetylases (HDACs). CQ accumulated the acetylation levels of
Lisa Hoffman et al.
Environmental toxicology and pharmacology, 34(2), 556-573 (2012-07-25)
The effects of the fungicides Maneb, Mancozeb, and Zineb were investigated in transformed colon cells, HT-29, Caco2 and non-transformed cells, CCD-18Co. Significant decreases in viability were observed with Maneb and Mancozeb in HT-29 and CCD-18Co (80-260μM), and Caco2 cells (40-180μM).
Michele K Sankako et al.
Pharmacological reports : PR, 64(6), 1537-1546 (2013-02-15)
The aim of this study was to evaluate the changes in testicular function of rats due to cigarette smoke exposure and the possible mechanism by which zinc protects against these alterations. Male Wistar rats (60 days old) were randomly divided
Shigeru Hishinuma et al.
Journal of pharmacological sciences, 119(3), 233-242 (2012-07-13)
We examined the regulatory mechanisms of the affinity of Gq protein-coupled histamine H(1)-receptors for histamine after histamine pretreatment in intact human U373 MG astrocytoma cells. In control cells, the displacement curves for histamine against the binding of 5 nM [(3)H]mepyramine
Angelina Lo Giudice et al.
Ecotoxicology (London, England), 22(2), 240-250 (2012-11-28)
The response of bacterial isolates from Antarctic sediments to polychlorinated biphenyls (Aroclor 1242 mixture), heavy metal salts (cadmium, copper, mercury and zinc) and antibiotics (ampicillin, chloramphenicol, kanamycin and streptomycin) was investigated. Overall, the ability to growth in the presence of
Nathalie Adam et al.
Nanotoxicology, 8(7), 709-717 (2013-07-11)
In this study, the effect of ZnO nanoparticles and ZnCl2 on growth, reproduction and accumulation of zinc in Daphnia magna was determined in a 21-day chronic toxicity test. A variety of techniques were used to distinguish the free zinc ion
Andrea M Hui et al.
Dermatologic clinics, 30(3), 503-515 (2012-07-18)
For melanoma treatment, the primary goal is complete removal with histologically negative margins. Mohs micrographic surgery (MMS) has been extensively used and studied for the treatment of nonmelanoma skin cancer, particularly at sites where tissue conservation is vital. The use
Kaushik Nath et al.
Environmental science and pollution research international, 20(6), 4030-4045 (2012-12-06)
Utilization of agrowaste materials for the production of activated carbon, as an excellent adsorbent with large surface area, is well established industrially, for dephenolation of wastewater. In the present work, dried pods of Prosopis cineraria-a novel and low-cost agrowaste material-were
Anne Müller et al.
PloS one, 8(1), e53347-e53347 (2013-01-22)
The G-protein coupled receptor 83 (GPR83) is an orphan G-protein coupled receptor for which the natural ligand(s) and signaling pathway(s) remain to be identified. Previous studies suggest a role of GPR83 in the regulation of thermogenesis and the control of
Hai-Long Jiang et al.
Journal of the American Chemical Society, 134(36), 14690-14693 (2012-08-22)
Reactions of ZrCl(4) and single or mixed linear dicarboxylic acids bearing methyl or azide groups lead to highly stable isoreticular metal-organic frameworks (MOFs) with content-tunable, accessible, reactive azide groups inside the large pores. These Zr-based MOFs offer an ideal platform
Anat Elmann et al.
Oxidative medicine and cellular longevity, 2012, 157598-157598 (2013-01-16)
Oxidative stress is involved in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's diseases. Astrocytes, the most abundant glial cells in the brain, protect neurons from reactive oxygen species (ROS) and provide them with trophic support, such as
E Hjortsø et al.
Intensive care medicine, 14(1), 17-24 (1988-01-01)
Five soldiers were injured by inhalation of hexite smoke (ZnCl2) during military training. Two soldiers, not wearing gas masks breathed hexite for 1 or 2 min, they slowly developed severe adult respiratory distress syndrome (ARDS) over the ensuing 2 weeks.
Kunitoshi Uchida et al.
The Journal of biological chemistry, 288(36), 25950-25955 (2013-07-26)
The transient receptor potential melastatin 5 (TRPM5) channel is a monovalent cation channel activated by intracellular Ca(2+). Expression of this channel is restricted to taste cells, the pancreas and brainstem, and is thought to be involved in controlling membrane potentials.
Yen-Hua Chen et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 166(1), 1-7 (2013-05-15)
The common carp is one of the few fish able to tolerate extremely low oxygen levels. These fish store zinc in their digestive tract tissue and head kidney at concentrations of 300-500μg/g of fresh tissue, which is 5-10 times higher
Molouk Beiromvand et al.
Preventive veterinary medicine, 109(1-2), 162-167 (2012-10-10)
Certain zoonotic parasites are enteropathogens in dogs that cause serious human disease such as cystic echinococcosis, human alveolar echinococcosis, visceral larva migrans, and ocular larva migrans. This study investigated the prevalence of intestinal parasites in dogs in the Chenaran County
Mayank Anand Gururani et al.
Plant science : an international journal of experimental plant biology, 198, 7-16 (2012-12-04)
Manganese stabilizing protein (MSP) is an important component of the Photosystem II (PSII) oxygen evolving complex. In our previous work, transgenic potato plants with reduced expression of MSP (MSP-As) were developed and their physiological and biochemical responses were studied. In
Elwin Molenbroek et al.
Dalton transactions (Cambridge, England : 2003), 42(8), 2973-2984 (2012-12-22)
In this work, the complexation of the bapbpy ligand to zinc dichloride is described (bapbpy = 6,6′-bis(2-aminopyridyl)-2,2′-bipyridine). The water-soluble, colorless complex [Zn(bapbpy)Cl]Cl·2H2O (compound 2·H2O) was synthesized; its X-ray crystal structure shows a mononuclear, pentacoordinated geometry with one chloride ligand in
Malgorzata M Brzóska et al.
Toxicology and applied pharmacology, 272(1), 208-220 (2013-06-04)
It was investigated whether protective influence of zinc (Zn) against cadmium (Cd)-induced disorders in bone metabolism may be related to its antioxidative properties and impact on the receptor activator of nuclear factor (NF)-κΒ (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) system. Numerous indices
Yingxiong Wang et al.
Bioresource technology, 143, 384-390 (2013-07-04)
The direct conversion of chitin biomass to 5-hydroxymethylfurfural (5-HMF) in ZnCl2 aqueous solution was studied systemically. D-Glucosamine (GlcNH2) was chosen as the model compound to investigate the reaction, and 5-HMF could be obtained in 21.9% yield with 99% conversion of
Masatoshi Ishida et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(45), 14329-14341 (2012-09-26)
The synthesis, characterization, photophysical properties, and theoretical analysis of a series of tetraaza porphyrin analogues (H-Pn: n=1-4) containing a dipyrrin subunit and an embedded 1,10-phenanthroline subunit are described. The meso-phenyl-substituted derivative (H-P1) interacts with a Mg(2+) salt (e.g., MgCl(2), MgBr(2)
Fiona Larner et al.
Environmental science & technology, 46(21), 12137-12145 (2012-10-12)
Zinc oxide nanoparticles (ZnO NPs) are widely used in commercial products and knowledge of their environmental fate is a priority for ecological protection. Here we synthesized model ZnO NPs that were made from and thus labeled with the stable isotope
Fen Li et al.
Environmental technology, 35(17-20), 2575-2581 (2014-08-26)
Sludge-activated carbons (SACs) prepared with excess of activated sludge are used to solve the problems of sludge disposal and odour pollution in a sewage treatment plant. For the preparation, ZnCl2, KOH and H2SO4 are used as activators, respectively. The structure
L M Skjolding et al.
Aquatic toxicology (Amsterdam, Netherlands), 157, 101-108 (2014-12-03)
The potential uptake and trophic transfer of nanoparticles (NP) is not well understood so far and for ZnO NP the data presented in peer-reviewed literature is limited. In this paper the influence of surface functionalization on the uptake and depuration
Jessica Duprez et al.
PloS one, 7(10), e46831-e46831 (2012-10-12)
Rat pancreatic islet cell apoptosis is minimal after prolonged culture in 10 mmol/l glucose (G10), largely increased in 5 mmol/l glucose (G5) and moderately increased in 30 mmol/l glucose (G30). This glucose-dependent asymmetric V-shaped profile is preceded by parallel changes
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