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93289

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Ximena Gutiérrez-Ramos et al.
Insect biochemistry and molecular biology, 122, 103412-103412 (2020-05-18)
Anastrepha ludens is a major pest of fruits including citrus and mangoes in Mexico and Central America with major economic and social impacts. Despite its importance, our knowledge on its embryonic development is scarce. Here, we report the first cytological...
Wang Xing et al.
Journal of receptor and signal transduction research, 41(5), 476-487 (2020-10-16)
MicroRNA (miRNA) is known to be involved in the pathological process of congenital heart disease (CHD), and nodal modulator1 (NOMO1) is a critical determinant of heart formation. The present study aims to discover the effect of miR-33a-5p and NOMO1 on...
Juliana L de Oliveira et al.
Lipids in health and disease, 10, 22-22 (2011-01-27)
Although lipids transfer through placenta is very limited, modification in dietary fatty acids can lead to implications in fetal and postnatal development. Trans fatty acid (TFA) intake during gestation and lactation have been reported to promote dyslipidemia and increase in...
J R Mellin et al.
Science (New York, N.Y.), 345(6199), 940-943 (2014-08-26)
Riboswitches are ligand-binding elements contained within the 5' untranslated regions of bacterial transcripts, which generally regulate expression of downstream open reading frames. Here, we show that in Listeria monocytogenes, a riboswitch that binds vitamin B12 controls expression of a noncoding...
Resveratrol inhibits the progression of cervical cancer by suppressing the transcription and expression of HPV E6 and E7 genes.
Sun, et al.
International Journal of Molecular Medicine, 47, 335-345 (2021)
Aitana M Castro Colabianchi et al.
Biology open, 10(2) (2021-02-11)
The blastula Chordin- and Noggin-expressing (BCNE) center comprises animal-dorsal and marginal-dorsal cells of the amphibian blastula and contains the precursors of the brain and the gastrula organizer. Previous findings suggested that the BCNE behaves as a homogeneous cell population that...
Kristina Curgali et al.
Acta histochemica, 120(1), 28-32 (2017-11-14)
The aim of our study was to analyse the possible protective effect of quercetin application during the jejunal ischemia-reperfusion injury (IRI) in rats. Quercetin was administered intraperitoneally 30min before 1h ischemia of superior mesenteric artery with following 24h lasting reperfusion...
Yu-Cheng Zhang et al.
The Journal of cell biology, 220(2) (2021-01-22)
Primary cilia protrude from the cell surface and have diverse roles during development and disease, which depends on the precise timing and control of cilia assembly and disassembly. Inactivation of assembly often causes cilia defects and underlies ciliopathy, while diseases...
Josephine Yu et al.
American journal of physiology. Endocrinology and metabolism, 321(1), E176-E189 (2021-06-15)
Almost 40% of adults worldwide are classified as overweight or obese. Exercise is a beneficial intervention in obesity, partly due to increases in mitochondrial activity and subsequent increases in nicotinamide adenine dinucleotide (NAD+), an important metabolic cofactor. Recent studies have...
Hao Zhang et al.
Molecular medicine reports, 22(2), 915-925 (2020-07-07)
Dilated cardiomyopathy (DCM) is a primary cardiomyopathy with high mortality. The aim of the present study was to identify the related genes in DCM. The four expression profiles (GSE17800, GSE21610, GSE42955 and GSE79962) downloaded from the Gene Expression Omnibus (GEO)...
Anna Marie Price et al.
Plant physiology, 147(4), 1898-1912 (2008-06-10)
Petals and leaves share common evolutionary origins but perform very different functions. However, few studies have compared leaf and petal senescence within the same species. Wallflower (Erysimum linifolium), an ornamental species closely related to Arabidopsis (Arabidopsis thaliana), provide a good...
Matthew G Frank et al.
Brain, behavior, and immunity, 80, 678-687 (2019-05-13)
Exposure to stressors primes neuroinflammatory responses to subsequent immune challenges and stress-induced glucocorticoids (GCs) play a mediating role in this phenomenon of neuroinflammatory priming. Recent evidence also suggests that the alarmin high-mobility group box-1 (HMGB1) and the microglial checkpoint receptor...
Gavin S Wilkie et al.
Molecular & cellular proteomics : MCP, 10(1), M110-M110 (2010-09-30)
Nuclear envelopes from liver and a neuroblastoma cell line have previously been analyzed by proteomics; however, most diseases associated with the nuclear envelope affect muscle. To determine whether muscle has unique nuclear envelope proteins, rat skeletal muscle nuclear envelopes were...
Tadeja Rezen et al.
BMC genomics, 10, 384-384 (2009-08-21)
Detoxification in the liver involves activation of nuclear receptors, such as the constitutive androstane receptor (CAR), which regulate downstream genes of xenobiotic metabolism. Frequently, the metabolism of endobiotics is also modulated, resulting in potentially harmful effects. We therefore used 1,4-Bis...
J B Buchanan et al.
Psychoneuroendocrinology, 33(6), 755-765 (2008-04-15)
Peripheral immune stimulation as well as certain types of psychological stress increases brain levels of inflammatory cytokines such as interleukin-1beta (IL-1beta), IL-6 and tumor necrosis factor alpha (TNFalpha). We have demonstrated that aged mice show greater increases in central inflammatory...
Ana M Martín-Hernández et al.
Journal of virology, 82(8), 4064-4071 (2008-02-15)
RNA silencing is a host defense mechanism that limits the accumulation and spread of viruses in infected plants. Correspondingly, plant viruses encode suppressors of silencing. In the positive-strand RNA virus Tobacco rattle virus (TRV), the suppressor of silencing is a...
María Muñoz et al.
Genetics, selection, evolution : GSE, 42, 23-23 (2010-06-26)
The aim of this work was to study the effects on litter size of variants of the porcine genes RBP4, ESR1 and IGF2, currently used in genetic tests for different purposes. Moreover, we investigated a possible effect of the interaction...
Gillian P Johnson et al.
Bone, 145, 115846-115846 (2021-01-16)
The benefits of physical loading to skeletal mass are well known. The primary cilium has emerged as an important organelle in bone mechanobiology/mechanotransduction, particularly in mesenchymal stem/stromal cells, yet the molecular mechanisms of cilium mechanotransduction are poorly understood. In this...
P Gómez et al.
Journal of virology, 83(23), 12378-12387 (2009-09-18)
Pepino mosaic virus (PepMV) is an emerging pathogen that causes severe economic losses in tomato crops (Solanum lycopersicum L.) in the Northern hemisphere, despite persistent attempts of control. In fact, it is considered one of the most significant viral diseases...
Chitvan Khajuria et al.
BMC genomics, 10, 286-286 (2009-06-30)
Lepidoptera represents more than 160,000 insect species which include some of the most devastating pests of crops, forests, and stored products. However, the genomic information on lepidopteran insects is very limited. Only a few studies have focused on developing expressed...
Zhao-Shan Liu et al.
Nature immunology, 20(1), 18-28 (2018-12-05)
Cyclic GMP-AMP synthase (cGAS) is a key sensor responsible for cytosolic DNA detection. Here we report that GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) is critical for DNA sensing and efficient activation of cGAS. G3BP1 enhanced DNA binding of cGAS...
Maria Oczkowicz et al.
Genetics and molecular biology, 33(4), 790-794 (2011-06-04)
The Drosophila-like homolog 1 (DLK1), a transmembrane signal protein similar to other members of the Notch/Delta/Serrate family, regulates the differentiation process in many types of mammalian cells. Callipyge sheep and DLK1 knockout mice are excellent examples of a fundamental role...
Arash Kianianmomeni et al.
Plant physiology, 151(1), 347-366 (2009-07-31)
Channelrhodopsins are light-gated ion channels involved in the photoresponses of microalgae. Here, we describe the characterization of two channelrhodopsins, Volvox channelrhodopsin-1 (VChR1) and VChR2, from the multicellular green alga Volvox carteri. Both are encoded by nuclear single copy genes and...
Yamei Zhou et al.
Investigative ophthalmology & visual science, 62(3), 37-37 (2021-03-26)
This study examined the role of the CSF1/CSF1Raxis in the crosstalk between choroidal vascular endothelial cells (CVECs) and macrophages during the formation of choroidal neovascularization (CNV). Quantitative reverse transcriptase (QRT)-PCR, Western blot and ELISA measured the production and release of...
Hyun-Ju Hwang et al.
Journal of experimental botany, 62(13), 4571-4581 (2011-06-01)
In Arabidopsis, inflorescence stem formation is a critical process in phase transition from the vegetative to the reproductive state. Although inflorescence stem development has been reported to depend on the expression of a variety of genes during floral induction and...
Tristan Cerisy et al.
Journal of bacteriology, 201(15) (2019-05-22)
The mechanisms by which bacteria uptake solutes across the cell membrane broadly impact their cellular energetics. Here, we use functional genomic, genetic, and biophysical approaches to reveal how Clostridium (Lachnoclostridium) phytofermentans, a model bacterium that ferments lignocellulosic biomass, uptakes plant...
Gandhi N Solayar et al.
BMC musculoskeletal disorders, 12, 247-247 (2011-11-01)
Current treatments for the prevention of thromboembolism include heparin and low-molecular weight heparins (LMWHs). A number of studies have suggested that long term administration of these drugs may adversely affect osteoblasts and therefore, bone metabolism. Xarelto™ (Rivaroxaban) is a new...
Blanca M Herrera et al.
BMC medical genomics, 2, 54-54 (2009-08-20)
MicroRNAs (miRNAs) are non-coding RNA molecules involved in post-transcriptional control of gene expression of a wide number of genes, including those involved in glucose homeostasis. Type 2 diabetes (T2D) is characterized by hyperglycaemia and defects in insulin secretion and action...
Xiuju Sun et al.
International journal of biological macromolecules, 119, 565-571 (2018-07-28)
In this study, the protective effect of valsartan against glycerol-induced acute kidney injury (AKI) in male albino rats was investigated. Valsartan is used to treat high blood pressure and congestive heart failure and can prolong lifespan following a heart attack....
Yael Friedman-Levi et al.
PLoS pathogens, 7(11), e1002350-e1002350 (2011-11-11)
Genetic prion diseases are late onset fatal neurodegenerative disorders linked to pathogenic mutations in the prion protein-encoding gene, PRNP. The most prevalent of these is the substitution of Glutamate for Lysine at codon 200 (E200K), causing genetic Creutzfeldt-Jakob disease (gCJD)...
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