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Maryam Parvas et al.
Developmental biology, 321(1), 51-63 (2008-07-18)
In vertebrates, early brain development takes place at the expanded anterior end of the neural tube, which is filled with embryonic cerebrospinal fluid (E-CSF). Most of the proteins contained within the E-CSF, which play crucial roles in CNS development, are
Molecular identification, immunolocalization, and functional activity of a vacuolar-type H+-ATPase in bovine rumen epithelium
Albrecht E, et al.
Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology, 178(2), 285-295 (2008)
James Zhe Hui et al.
Small (Weinheim an der Bergstrasse, Germany), 10(16), 3354-3363 (2014-04-15)
Antibodies, most commonly IgGs, have been widely used as targeting ligands in research and therapeutic applications due to their wide array of targets, high specificity and proven efficacy. Many of these applications require antibodies to be conjugated onto surfaces (e.g.
Daniel M Houslay et al.
Science signaling, 9(441), ra82-ra82 (2016-08-18)
Class I phosphoinositide 3-kinases (PI3Ks) catalyze production of the lipid messenger phosphatidylinositol 3,4,5-trisphosphate (PIP3), which plays a central role in a complex signaling network regulating cell growth, survival, and movement. This network is overactivated in cancer and inflammation, and there
Eri Yasuoka et al.
Journal of molecular medicine (Berlin, Germany), 85(3), 283-292 (2006-10-31)
Allergic rhinitis (AR) is one of the most common chronic diseases. Although current medications are highly effective in controlling its symptoms, they do not reverse the allergen-specific hypersensitivities that underlie the disease. Immunoglobulin E is a key mediator of AR
Helena Zientek-Targosz et al.
Molecular cancer, 7, 51-51 (2008-06-07)
Widely accepted somatic mutation theory of carcinogenesis states that mutations in oncogenes and tumor suppressor genes in genomes of somatic cells is the cause of neoplastic transformation. Identifying frequent mutations in cancer cells suggests the involvement of mutant genes in
Wanzhen Jiao et al.
Scientific reports, 9(1), 15339-15339 (2019-10-28)
Vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) plays a crucial role in breakdown of the blood-retinal barrier due to hyperpermeability in diabetic retinopathy (DR). However, the distinct signaling driven by VEGF and PlGF in the pathogenesis of
Yasmin Ahmad et al.
Scientific reports, 5, 10681-10681 (2015-05-30)
Exposure to high altitude induces physiological responses due to hypoxia. Lungs being at the first level to face the alterations in oxygen levels are critical to counter and balance these changes. Studies have been done analysing pulmonary proteome alterations in
Reversibility of scrapie-associated prion protein aggregation.
Callahan, et al.
The Journal of Biological Chemistry, 276, 28022-28028 (2021)
Bovine serum albumin interactions with metal complexes
Topalua T, et al.
Clujul Medical (1957), 87(4), 215-215 (2014)
Guilherme C Lechuga et al.
International journal of molecular sciences, 22(16) (2021-08-28)
(1) Background: coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been linked to hematological dysfunctions, but there are little experimental data that explain this. Spike (S) and Nucleoprotein (N) proteins have been putatively associated
Fatty acids of Treponema pallidum and Borrelia burgdorferi lipoproteins
Belisle JT, et al.
Journal of Bacteriology, 176(2), 2151-2157 (1994)
Structural changes during the unfolding of Bovine serum albumin in the presence of urea: A small-angle neutron scattering study
Das A, et al.
Pramana, 63(2), 363-368 (2004)
J T Belisle et al.
Journal of bacteriology, 176(8), 2151-2157 (1994-04-01)
A fundamental ultrastructural feature shared by the spirochetal pathogens Treponema pallidum subsp. pallidum (T. pallidum) and Borrelia burgdorferi, the etiological agents of venereal syphilis and Lyme disease, respectively, is that their most abundant membrane proteins contain covalently attached fatty acids.
Marcus Lockowandt et al.
Journal of neuroscience methods, 336, 108542-108542 (2020-02-06)
To target specific neuronal populations by gene transfer is challenging. A complicating fact is that populations of neurons may have opposing roles despite being found adjacent to each other. One example is the medium spiny neurons of the striatum. These
Nadja Sparding et al.
PloS one, 9(11), e112876-e112876 (2014-11-18)
After a potential biological incident the sampling strategy and sample analysis are crucial for the outcome of the investigation and identification. In this study, we have developed a simple sandwich ELISA based on commercial components to quantify BSA (used as
Chang Seok Bang et al.
Journal of ginseng research, 38(3), 167-172 (2014-11-08)
Roles of immune reaction and toll-like receptor-4 (TLR-4) have widely been established in the pathogenesis of alcoholic liver disease (ALD). We evaluated the biologic efficacy of Korean Red Ginseng (KRG), urushiol, and probiotics (Lactobacillus rhamnosus R0011 and Lactobacillus acidophilus R0052)
David W Nees et al.
Investigative ophthalmology & visual science, 44(8), 3339-3345 (2003-07-29)
To compare the abundance and spatial distribution of serum albumin in the mouse and bovine cornea. Serum albumin from cornea was separated from transketolase by SDS-PAGE (+/-dithiothreitol [DTT]) and identified by peptide sequencing and immunoblot analyses. The fractional content of
Samantha Zinkie et al.
Cell stress & chaperones, 18(6), 745-758 (2013-04-19)
Clusterin, a protein chaperone found at high levels in physiological fluids, is expressed in nervous tissue and upregulated in several neurological diseases. To assess relevance to amyotrophic lateral sclerosis (ALS) and other motor neuron disorders, clusterin expression was evaluated using
Katarina Novotna et al.
Materials (Basel, Switzerland), 6(5), 1632-1655 (2013-04-29)
Cell colonization of synthetic polymers can be regulated by physical and chemical modifications of the polymer surface. High-density and low-density polyethylene (HDPE and LDPE) were therefore activated with Ar⁺ plasma and grafted with fibronectin (Fn) or bovine serum albumin (BSA).
Marie Louise Gross et al.
Kidney international, 62(1), 51-59 (2002-06-26)
A substantial body of experimental evidence suggests that protein loading causes activation of proximal tubular epithelial cells with consecutive interstitial fibrosis. These studies have mostly been performed using mammalian in vivo models of glomerular damage or tissue cultures of mammalian
W Ye et al.
The Journal of biological chemistry, 270(18), 10933-10939 (1995-05-05)
We separately expressed the 58-kDa C-terminal, 42-kDa middle, 16-kDa C-terminal, and 33-kDa N-terminal regions of AP-3 (also called F1-20, AP180, NP185, and pp155), and determined their clathrin binding and assembly properties. The 58-kDa C-terminal region of AP-3 is able to
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