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Kathryn Geldart et al.
Applied and environmental microbiology, 81(11), 3889-3897 (2015-04-05)
Antibiotic-resistant enterococcal infections are a major concern in hospitals where patients with compromised immunity are readily infected. Enterococcus faecium bacteria are of particular interest as these pathogens account for over 80% of vancomycin-resistant enterococcal infections. Antimicrobial peptides (AMPs) produced at
Monika Jusko et al.
Journal of immunology (Baltimore, Md. : 1950), 195(5), 2231-2240 (2015-07-26)
Recent reports focusing on virulence factors of periodontal pathogens implicated proteinases as major determinants of remarkable pathogenicity of these species, with special emphasis on their capacity to modulate complement activity. In particular, bacteria-mediated cleavage of C5 and subsequent release of
Wenfeng Liu et al.
BMC research notes, 13(1), 63-63 (2020-02-09)
The golden color of Staphylococcus aureus is due to the synthesis of carotenoid pigments. In Gram-negative bacteria, Hfq is a global posttranscriptional regulator, but its function in S. aureus remains obscure. The absence of Hfq in S. aureus was reported
Symposium on antimicrobial therapy. X. Chloramphenicol, clindamycin, and metronidazole.
R A Greenfield
The Journal of the Oklahoma State Medical Association, 86(7), 336-341 (1993-07-01)
Meseret Ashenafi et al.
Molecular and cellular biochemistry, 400(1-2), 9-15 (2014-10-31)
Recently, we showed that the fused chorismate-utilizing enzyme from the antibiotic-producing soil bacterium Streptomyces venezuelae is an anthranilate synthase (designated SvAS), not a 2-amino-2-deoxyisochorismate (ADIC) synthase, as was predicted based on its amino acid sequence similarity to the phenazine biosynthetic
Jing Xu et al.
Food chemistry, 134(4), 2526-2531 (2013-02-28)
In this research, magnetic beads-based enzyme immunoassays were investigated for rapid analysis of chloramphenicol (CAP) in milk. To improve sensitivity of CAP determination, two kinds of immunomagnetic separation methods were designed and compared. Magnetic polystyrene microspheres were conjugated with anti-CAP
Luís França et al.
PloS one, 10(10), e0141152-e0141152 (2015-10-30)
Over a period of ten months a total of 5618 cord blood units (CBU) were screened for microbial contamination under routine conditions. The antibiotic resistance profile for all isolates was also examined using ATB strips. The detection rate for culture
Calvin M Schmidt et al.
eLife, 10 (2021-04-17)
Ribozyme switches are a class of RNA-encoded genetic switch that support conditional regulation of gene expression across diverse organisms. An improved elucidation of the relationships between sequence, structure, and activity can improve our capacity for de novo rational design of
Eric H Clifton et al.
PloS one, 13(3), e0194815-e0194815 (2018-03-23)
Terrestrial plants can harbor endophytic fungi that may induce changes in plant physiology that in turn affect interactions with herbivorous insects. We evaluated whether the application of entomopathogenic fungi Beauveria bassiana and Metarhizium brunneum to soybean seeds could become endophytic
Katarzyna Wiśniewska et al.
Folia microbiologica, 59(6), 465-471 (2014-05-16)
Staphylococcus aureus is a leading cause of bloodstream infections (BSI) and diseases that may be caused by hematogenous spread. The staphylococcal adhesin, for which the association with the infections emerging as a complication of septicemia has been well documented, is
Xinpeng Jiang et al.
Applied microbiology and biotechnology, 98(19), 8301-8312 (2014-07-06)
The role of muramyl dipeptide (MDP) and tuftsin in oral immune adjustment remains unclear, particularly in a Lactobacillus casei (L. casei) vaccine. To address this, we investigated the effects of different repetitive peptides expressed by L. casei, specifically the MDP
Omer Goldberger et al.
iScience, 24(10), 103096-103096 (2021-10-09)
The omnigenic/polygenic theory, which states that complex traits are not shaped by single/few genes, but by situation-specific large networks, offers an explanation for a major enigma in microbiology: deletion of specific small RNAs (sRNAs) playing key roles in various aspects
Yifeng Wei et al.
Biochemistry, 54(47), 7019-7028 (2015-11-05)
Two subtypes of class III anaerobic ribonucleotide reductases (RNRs) studied so far couple the reduction of ribonucleotides to the oxidation of formate, or the oxidation of NADPH via thioredoxin and thioredoxin reductase. Certain methanogenic archaea contain a phylogenetically distinct third
Carla B Schubiger et al.
Applied and environmental microbiology, 81(2), 658-665 (2014-11-09)
Flavobacterium psychrophilum causes bacterial cold-water disease in multiple fish species, including salmonids. An autochthonous Enterobacter strain (C6-6) inhibits the in vitro growth of F. psychrophilum, and when ingested as a putative probiotic, it provides protection against injection challenge with F.
Maureen Hummel et al.
Journal of proteomics, 128, 436-449 (2015-08-02)
Arabidopsis thaliana cytosolic ribosomes are large complexes containing eighty-one distinct ribosomal proteins (r-proteins), four ribosomal RNAs (rRNA) and a plethora of associated (non-ribosomal) proteins. In plants, r-proteins of cytosolic ribosomes are each encoded by two to seven different expressed and
S Coppenhagen-Glazer et al.
Infection and immunity, 83(3), 1104-1113 (2015-01-07)
Fusobacterium nucleatum is a common oral anaerobe involved in periodontitis that is known to translocate and cause intrauterine infections. In the oral environment, F. nucleatum adheres to a large diversity of species, facilitating their colonization and creating biological bridges that
Sabrina I Green et al.
Infection and immunity, 83(8), 3243-3256 (2015-06-03)
Escherichia coli is a major cause of life-threatening infections in patients with neutropenia, particularly those receiving chemotherapy for the treatment of cancer. In most cases, these infections originate from opportunistic strains living within the patient's gastrointestinal tract which then translocate
Kanghui Yang et al.
Mini reviews in medicinal chemistry, 9(11), 1329-1341 (2009-11-26)
Chloramphenicol (CAP) is a widely used broad-spectrum antibiotic. As the precursor of CAP, chloramphenicol bases are stereochemically pure agents and could be used as resolution agents, chiral catalysts and so on. This review summarizes these applications and discusses the structural
Saurabh Bhattacharya et al.
Cell reports, 27(2), 334-342 (2019-04-02)
We have previously described the existence of membranous nanotubes, bridging adjacent bacteria, facilitating intercellular trafficking of nutrients, cytoplasmic proteins, and even plasmids, yet components enabling their biogenesis remain elusive. Here we reveal the identity of a molecular apparatus providing a
Targeting antibacterial agents by using drug-carrying filamentous bacteriophages.
Yacoby I et al.
Antimicrobial Agents and Chemotherapy, 50, 2087-2087 (2006)
Daniel S Leventhal et al.
Nature communications, 11(1), 2739-2739 (2020-06-03)
Synthetic biology is a powerful tool to create therapeutics which can be rationally designed to enable unique and combinatorial functionalities. Here we utilize non-pathogenic E coli Nissle as a versatile platform for the development of a living biotherapeutic for the
Robert W Behle et al.
Journal of economic entomology, 108(4), 1587-1595 (2015-10-16)
Experimental and commercial preparations of Metarhizium brunneum (Petch) strain F52 were evaluated for control of Japanese beetle, Popillia japonica Newman (Coleoptera: Scarbaeidae), larvae (white grubs) in the laboratory and under field conditions. Experimental preparations consisted of granule and liquid formulations
Alexander Zink et al.
Mycoses, 57(12), 765-770 (2014-09-02)
After experiencing an unusually high number of Microsporum (M.) audouinii infections at our hospital within only a few weeks, we began to investigate and control an outbreak in Munich, Germany. Main goals of our health management were to treat infected
R E Wolfenden et al.
Poultry science, 89(11), 2370-2379 (2010-10-19)
Attenuated Salmonella Enteriditis (ΔSE) recombinant vaccine vectors incorporating a Salmonella flagellar filament protein (fliC) subunit, a putative cell-mediated epitope, for expression of the lamB gene (encoding a maltose outer membrane porin), with or without co-expression of a putative immune-enhancing CD154
Anthony J Brzoska et al.
PloS one, 8(2), e56090-e56090 (2013-02-15)
Members of the genus Acinetobacter have been the focus recent attention due to both their clinical significance and application to molecular biology. The soil commensal bacterium Acinetobacter baylyi ADP1 has been proposed as a model system for molecular and genetic
Sandra Cabo Verde et al.
Research in microbiology, 166(7), 557-563 (2015-04-15)
Poor hospital indoor air quality (IAQ) may lead to hospital-acquired infections, sick hospital syndrome and various occupational hazards. Air-control measures are crucial for reducing dissemination of airborne biological particles in hospitals. The objective of this study was to perform a
Valentina Franceschi et al.
PLoS neglected tropical diseases, 9(6), e0003850-e0003850 (2015-06-19)
Monkeypox virus (MPXV) is the etiological agent of human (MPX). It is an emerging orthopoxvirus zoonosis in the tropical rain forest of Africa and is endemic in the Congo-basin and sporadic in West Africa; it remains a tropical neglected disease
Izaskun García-Mantrana et al.
International journal of food microbiology, 216, 18-24 (2015-09-19)
Phytases are enzymes capable of sequentially dephosphorylating phytic acid to products of lower chelating capacity and higher solubility, abolishing its inhibitory effect on intestinal mineral absorption. Genetic constructions were made for expressing two phytases from bifidobacteria in Lactobacillus casei under
Hayam M Lotfy et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 148, 328-337 (2015-04-25)
Smart spectrophotometric methods have been applied and validated for the simultaneous determination of a binary mixture of chloramphenicol (CPL) and prednisolone acetate (PA) without preliminary separation. Two novel methods have been developed; the first method depends upon advanced absorbance subtraction
Brian R Tuinema et al.
mBio, 5(6), e01886-e01886 (2014-11-27)
Neutrophils engulf and kill bacteria using oxidative and nonoxidative mechanisms. Despite robust antimicrobial activity, neutrophils are impaired in directing Salmonella clearance and harbor viable intracellular bacteria during early stages of infection that can subsequently escape to more-permissive cell types. The
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