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Content Type:Technical Article
Showing 1-16 of 16 results
NF-κB and Inflammation
Chronic inflammation is an underlying factor in the development and progression of many of the chronic diseases of aging, such as arthritis, atherosclerosis, diabetes, and cancer.
Fatty Acid Synthesis and Metabolism in Cancer Cells
Information on fatty acid synthesis and metabolism in cancer cells. Learn how proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sources or are...
Cell Migration & Invasion Assays
Metastasis is the cumulative result of multiple changes in tumor cells. Explore tumor metastasis employing various cell migration and invasion assays like Boyden chamber assay, Millicell® µ-Migration Assay and in vitro scratch assay.
Superoxide Dismutase
Enzyme Explorer Product Application Index for Superoxide Dismutase offered by us online. Superoxide Dismutase (SOD) catalyzes the reduction of superoxide anions to hydrogen peroxide.
Nucleotide Synthesis in Cancer Cells
Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA.
Folic Acid Metabolism in Cancer
This issue of Biofiles reviews some of our newest and most innovative technologies and their specific applications toward cancer research. In preparing this issue of Biofiles, one is reminded how complex the disease of cancer is, and how difficult it...
Dynamic Live Cell Imaging of Caspase Mediated Apoptosis and Cellular Hypoxia in Lymphocytes and Cancer Cells Using the CellASIC® ONIX2 Microfluidic Platform
Application note on how the CellASIC® ONIX2 microfluidic system can be used to analyze caspase-3 mediated apoptosis/cell death and cellular hypoxia in live immune and cancer cell lines.
5 Reasons Cancer Researchers Adopt 3D Cell Culture: A Review of Recent Literature
Numerous cancer model systems are available to investigate disease mechanisms and to screen therapies. While all of the models have contributed critical information about cancer biology.
Epidermal Growth Factor Receptor (EGFR) Signaling
Review EGF/EGFR signaling (epidermal growth factor receptor) and find links to related products.
3D Neurosphere Culture Media
3D neurosphere culture protocol to expand human U-87 MG glioblastoma cells in serum-free/xeno-free stem cell culture media. Explore over 350 PromoCell products on Sigma.com.
Apoptosis Assays
Cellular apoptosis assays to detect programmed cell death using Annexin V, Caspase and TUNEL DNA fragmentation assays.
TokeOni: Properties and Applications
Bioluminescence imaging (BLI) systems allows for high-sensitive and noninvasive monitoring of cell proliferation, activity of signaling pathways and protein-protein interactions in living tissues.
Co-culture of Tumor and Stromal Cells in TrueGel3D™ Hydrogels
TrueGel3D™ synthetic hydrogel can be used to study co-culture of tumor and stromal cells.
Oncogenes and Tumor Suppressors Reprogram Metabolism
We present an article about how proliferating cells require the biosynthesis of structural components for biomass production and for genomic replication.
Atto Dyes for Superior Fluorescent Imaging
Atto dyes are a series of fluorescent dyes that meet the critical needs of modern fluorescent technologies.
Tissue Markers for Cancer Diagnostics
Immunohistochemistry (IHC) represents an indispensable tool in cancer diagnostics.