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GF93750419

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Shuichi Sekine et al.
Toxicology and applied pharmacology, 282(3), 237-243 (2014-12-30)
Patients with long-lasting hepatitis C virus (HCV) infection are at major risk of hepatocellular carcinoma (HCC). Iron accumulation in the livers of these patients is thought to exacerbate conditions of oxidative stress. Transgenic mice that express the HCV core protein...
Iadviga Zhelezinskaia et al.
Science (New York, N.Y.), 346(6210), 742-744 (2014-11-08)
The minor extent of sulfur isotope fractionation preserved in many Neoarchean sedimentary successions suggests that sulfate-reducing microorganisms played an insignificant role in ancient marine environments, despite evidence that these organisms evolved much earlier. We present bulk, microdrilled, and ion probe...
Ferric carboxymaltose increases epoetin-α response and prevents iron deficiency before elective orthopaedic surgery.
E Rineau et al.
British journal of anaesthesia, 113(2), 296-298 (2014-07-20)
[Iron deficiency anaemia].
Hermann S Füessl
MMW Fortschritte der Medizin, 156(3), 55-57 (2014-06-19)
Marie Laval et al.
American journal of physiology. Gastrointestinal and liver physiology, 308(2), G76-G84 (2014-11-15)
Hypoxia, or a low concentration of O2, is encountered in humans undertaking activities such as mountain climbing and scuba diving and is important pathophysiologically as a limiting factor in tumor growth. Although data on the interplay between hypoxia and gastrins...
Microcytic anemia.
Frank Brodzik et al.
The New England journal of medicine, 371(26), 2535-2536 (2014-12-30)
Raed A Al-Juboori et al.
Ultrasonics, 57, 18-30 (2014-12-03)
Obtaining accurate power characteristics of ultrasonic treatment systems is an important step towards their industrial scalability. Calorimetric measurements are most commonly used for quantifying the dissipated ultrasonic power. However, accuracy of these measurements is affected by various heat losses, especially...
Bo-Young Yoon et al.
Biochemical and biophysical research communications, 446(4), 971-976 (2014-03-25)
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a facultative intracellular pathogen with the ability to survive and replicate in macrophages. Periplasmic copper binding protein CueP is known to confer copper resistance to S. Typhimurium, and has been implicated in ROS...
Bhupendra K Sen et al.
Bulletin of environmental contamination and toxicology, 93(5), 549-554 (2014-09-27)
The removal of phenolic compounds, i.e., o-cresol, m-cresol, and p-cresol from aqueous solution have been evaluated employing activated carbon (AC) coated with polymer supported iron nanoparticles (FeNPs). The synthesized FeNPs were characterized by scanning electron microscope and X-ray diffraction analysis....
M Pasalar et al.
Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 20(11), 726-731 (2015-01-21)
This study investigated the prevalence of iron-deficiency anaemia, glucose-6-phosphate dehydrogenase (G6PD) deficiency and β-thalassaemia trait among Arab migrating nomad children in southern Islamic Republic of Iran. Blood samples were analysed from 134 schoolchildren aged < 18 years (51 males, 83...
Yongwei Song et al.
Environmental technology, 35(17-20), 2538-2545 (2014-08-26)
It is well documented that bioleaching with the co-inoculation ofAcidithiobacillus ferrooxidans and Acidithiobacillus thiooxidans can drastically enhance sludge dewaterability under ambient temperature condition, but little information on low temperature effect on bioleached sludge dewaterability is available. In this study, the...
V N Lukach et al.
Anesteziologiia i reanimatologiia, (1)(1), 78-81 (2014-04-23)
The article reviews recent studies of iron exchange and its role in a traumatic disease and traumatic shock. The review stresses a relationship of iron metabolism disturbance with free radical oxidation, lipid peroxidation and multiple organ dysfunctions. The article deals...
Jill Harned et al.
Biochimica et biophysica acta, 1840(10), 3138-3144 (2014-06-28)
Blood-barrier systems are essential in controlling iron levels in organs such as the brain and eye, both of which experience hypoxia in pathological conditions. While hypoxia's effects on numerous iron regulatory and storage proteins have been studied, little is known...
Scott J Dixon et al.
Nature chemical biology, 10(1), 9-17 (2013-12-19)
The transition metal iron is essential for life, yet potentially toxic iron-catalyzed reactive oxygen species (ROS) are unavoidable in an oxygen-rich environment. Iron and ROS are increasingly recognized as important initiators and mediators of cell death in a variety of...
Diego Moretti et al.
Annals of the New York Academy of Sciences, 1312, 54-65 (2013-12-18)
Several strategies appear suitable to improve iron and zinc bioavailability from fortified maize, and fortification per se will increase the intake of bioavailable iron and zinc. Corn masa flour or whole maize should be fortified with sodium iron ethylenediaminetetraacetate (NaFeEDTA)...
Jun-Won Jang et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 59(12), 2503-2507 (2009-06-23)
Zero valent iron has been successfully used for the degradation of a wide range of contaminants. However, this reaction of using ZVI particle produces a large quantity of iron sludge. To solve the problem, we report the synthesis of self-organized...
Ewelina Łukaszyk et al.
Przeglad lekarski, 71(2), 95-97 (2014-07-16)
Subclinical inflammation is one of the key mechanisms responsible for the development and progression of chronic kidney disease. It may stem from uremia, ongoing inflammation in kidney as well as latent bacterial and viral infections. Inflammation also plays a significant...
The role of intravenous iron for the treatment of restless legs syndrome.
Michael Auerbach
American journal of hematology, 89(10), 1016-1016 (2014-08-05)
Catherine F M Bowden et al.
Biochemistry, 53(14), 2286-2294 (2014-03-22)
The Isd (iron-regulated surface determinant) system is a multiprotein transporter that allows bacterium Staphylococcus aureus to take up iron from hemoglobin (Hb) during human infection. In this system, IsdB is a cell wall-anchored surface protein that contains two near iron...
Oliver M Theusinger
Praxis, 103(21), 1257-1262 (2014-10-12)
Blood transfusions are in general considered as lifesaving. Current data and evidence show, that blood transfusions are associated with increased morbidity and mortality, and this apparently dose-dependent. Basic research and results from randomized controlled trials show a causal relationship between...
Julia Steuber et al.
Nature, 516(7529), 62-67 (2014-12-05)
NADH oxidation in the respiratory chain is coupled to ion translocation across the membrane to build up an electrochemical gradient. The sodium-translocating NADH:quinone oxidoreductase (Na(+)-NQR), a membrane protein complex widespread among pathogenic bacteria, consists of six subunits, NqrA, B, C...
James C Barton et al.
The American journal of the medical sciences, 349(1), 50-55 (2015-01-07)
Primary iron overload in African Americans has been reported predominantly from autopsy studies. We characterized hepatic iron phenotypes in 83 African Americans who underwent liver biopsy during the interval 1990 to 1995. We tabulated pathology report form data, iron grades...
Satoshi Wakai et al.
Microbial ecology, 68(3), 519-527 (2014-05-28)
Elemental iodine is produced in Japan from underground brine (fossil salt water). Carbon steel pipes in an iodine production facility at Chiba, Japan, for brine conveyance were found to corrode more rapidly than those in other facilities. The corroding activity...
Lucie Y Guo et al.
Experimental eye research, 129, 31-37 (2014-12-03)
Age-related macular degeneration (AMD) is the most common cause of blindness among older adults in developed countries, and retinal iron accumulation may exacerbate the disease. Iron can upregulate the production of amyloid precursor protein (APP). Since amyloid-β (Aβ), a byproduct...
Vivek Kumar Srivastava et al.
The Biochemical journal, 463(1), 103-114 (2014-07-06)
Iron is an essential nutrient for all living organisms and human pathogens employ a battery of factors to scavenge iron from the high-affinity iron-binding host proteins. In the present study, we have elucidated, via a candidate gene approach, major iron...
Sandra Isabel Escobar-Megchún et al.
Journal of water and health, 12(4), 722-726 (2014-12-05)
This study relates to a method for evaluating the degradation efficiency of Ascaris lumbricoides eggs through a Fenton reaction, using hydrogen peroxide (H2O2) at 100, 250, and 500 mg/L, ferrous sulfate (FeSO4) at 458 mg/L Fe(2+) and pH values of...
Non-intravenous approaches to iron therapy in chronic kidney disease: will it improve the benefit-to-risk ratio?
Anatole Besarab
Nephrology news & issues, 28(2), 12-12 (2014-03-22)
Crystal D Karakochuk et al.
The Journal of nutrition, 145(1), 134-142 (2014-12-21)
Anemia is common in Cambodian women. Potential causes include micronutrient deficiencies, genetic hemoglobin disorders, inflammation, and disease. We aimed to investigate factors associated with anemia (low hemoglobin concentration) in rural Cambodian women (18-45 y) and to investigate the relations between...
Florence Lima et al.
Environmental and molecular mutagenesis, 55(3), 266-277 (2014-04-12)
DNA methylation is an epigenetic mechanism that drives phenotype and that can be altered by environmental exposures including radiation. The majority of human radiation exposures occur in a relatively low dose range; however, the biological response to low dose radiation...
Koichiro Uto et al.
Journal of nanoscience and nanotechnology, 14(4), 3193-3201 (2014-04-17)
(Apo)ferritins are cage-shaped proteins which have recently received a great deal of attention because the inner cavity of the protein shell can be used as a size-restricted reaction field for the synthesis of nanomaterials. The biomineralization behavior and inorganic nanoparticle...
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