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N6136

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Occupational allergic contact dermatitis of the ears caused by thiurams in a headset.
Claudia Pföhler et al.
Contact dermatitis, 65(4), 242-243 (2011-09-13)
Rayetta G Henderson et al.
Regulatory toxicology and pharmacology : RTP, 63(1), 20-28 (2012-03-01)
In vitro metal ion bioaccessibility, as a measure of bioavailability, can be used to read-across toxicity information from data-rich, source substances to data-poor, target substances. To meet the data requirements for oral systemic toxicity endpoints under the REACH Regulation in
Kaoru Onami et al.
The Journal of investigative dermatology, 134(7), 1951-1960 (2014-02-18)
Although extracellular adenosine 5'-triphosphate (eATP) has a crucial role in the sensitization phase of contact hypersensitivity (CHS), the mechanism by which hapten causes keratinocyte cell death and ATP release is unknown. We examined the time course of cell death, reactive
Jenilee Way et al.
Nuclear medicine and biology, 40(3), 430-436 (2013-01-12)
4-[(18)F]Fluorobenzylamine ([(18)F]FBA) is an important building block for the synthesis of (18)F-labeled compounds. Synthesis of [(18)F]FBA usually involves application of strong reducing agents like LiAlH4 which is challenging to handle in automated synthesis units (ASUs). Therefore, alternative methods for the
Kusaï Alomar et al.
Journal of inorganic biochemistry, 126, 76-83 (2013-06-25)
The reaction of nickel(II), copper(II) chlorides and cadmium(II) chloride and bromide with thiophene-2,3-dicarboxaldehyde bis(thiosemicarbazone) (2,3BTSTCH2) leads to a series of new complexes: [Ni(2,3BTSTCH)]Cl, [Cu(2,3BTSTC)], [CdCl2(2,3BTSTCH2)] and [CdBr2(2,3BTSTCH2)]. The crystal structures of the ligand and of [Ni(2,3BTSTCH)]Cl complex have been determined.
Jian Wang et al.
Nanoscale research letters, 10(1), 461-461 (2015-12-03)
Zn-doped NiO two-dimensional grainy films on glass substrates are shown to be an ammonia-sensing material with excellent comprehensive performance, which could real-time detect and monitor ammonia (NH3) in the surrounding environment. The morphology and structure analysis indicated that the as-fabricated
James Townsend et al.
ACS nano, 8(7), 6970-6978 (2014-06-21)
We report the fabrication of flexible chains of ferromagnetic Ni nanoparticles that possess the ability to adapt other than the typically observed rigid (nearly) straight configurations in the absence of an external magnetic field. The dynamic mobility of the ferromagnetic
Robert M Howlett et al.
Microbiology (Reading, England), 158(Pt 6), 1645-1655 (2012-03-10)
Campylobacter jejuni is a human pathogen of worldwide significance. It is commensal in the gut of many birds and mammals, where hydrogen is a readily available electron donor. The bacterium possesses a single membrane-bound, periplasmic-facing NiFe uptake hydrogenase that depends
Jason P Covy et al.
Journal of neuroscience research, 90(12), 2306-2316 (2012-08-01)
Mutations in ATP13A2, which encodes a lysosomal P-type ATPase of unknown function, cause an autosomal recessive parkinsonian syndrome. With mammalian cells, we show that ATP13A2 expression protects against manganese and nickel toxicity, in addition to proteasomal, mitochondrial, and oxidative stress.
Bangyuan Wu et al.
Biological trace element research, 151(2), 234-239 (2012-11-28)
Cytokines are immunoregulatory proteins which play an important role in the immune system. The purpose of this study was to examine the serum cytokine contents including interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-10 (IL-10), interferon gamma (IFN-γ), and tumor necrosis
Raziyeh Akbarzadeh et al.
Dalton transactions (Cambridge, England : 2003), 43(44), 16745-16753 (2014-10-04)
A NiS2 nanostructure with a protective layer of Ni(2+) and SO4(2-) ions around it has been successfully synthesized using the Ni(II)-Salen (Salen = N,N'-bis(salicylidene)ethylenediamine) complex via a simple solvothermal approach in the presence of anhydrous sodium thiosulfate (Na2S2O3) as sulfur
O M Vasyliv et al.
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 75(2), 37-44 (2013-06-01)
Superoxide dismutase, as one of the enzymes of cells' antioxidant defensive system, catalyzes superoxide anion-radical (O2-) dismutation with O2 and H2O2 forming. The influence of such transition metal compounds, as FeSO4, FeCl3, MnCl2, NiCl2, and CoCl2 on superoxide dismutase activity
William G Brumbaugh et al.
Environmental toxicology and chemistry, 32(11), 2482-2494 (2013-05-10)
Two spiking methods were compared and nickel (Ni) partitioning was evaluated during a series of toxicity tests with 8 different freshwater sediments having a range of physicochemical characteristics. A 2-step spiking approach with immediate pH adjustment by addition of NaOH
Studies on the genotoxic effect of nickel chloride in mice and the possible protective role of soybean seeds extracts
Fahmy MA, et al.
Global Journal of Pharmacology, 8(4), 625-634 (2014)
John M Besser et al.
Environmental toxicology and chemistry, 32(11), 2495-2506 (2013-05-10)
This study evaluated the chronic toxicity of Ni-spiked freshwater sediments to benthic invertebrates. A 2-step spiking procedure (spiking and sediment dilution) and a 2-stage equilibration period (10 wk anaerobic and 1 wk aerobic) were used to spike 8 freshwater sediments with wide
Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium
Salnikow K and Zhitkovich A
Chemical Research in Toxicology, 21(1), 28-44 (2007)
Zeinhom M El-Bahy et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 92, 105-112 (2012-03-27)
Cast technique was used to prepare films of sodium carboxymethyl cellulose (CMC) doped with different ratios of NiCl(2)·6H(2)O in the range of 0-40Ni(2+) wt.%. Thermal analysis (DTA) in the range of 25-600°C and dielectric properties in the temperature range of
Nonrandom chromosomal alterations in nickel-transformed Chinese hamster embryo cells
Conway K and Costa M
Cancer Research, 49(21), 6032-6038 (1989)
Chih-Hsien Wu et al.
The Journal of biological chemistry, 287(30), 25292-25302 (2012-06-01)
Epithelial-mesenchymal transition (EMT) is considered a critical event in the pathogenesis of lung fibrosis and tumor metastasis. During EMT, the expression of differentiation markers switches from cell-cell junction proteins such as E-cadherin to mesenchymal markers such as fibronectin. Although nickel-containing
R Prabhakaran et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 18(2), 233-247 (2013-01-01)
Three new nickel(II) thiosemicarbazone complexes have been synthesized and characterized by analytical, spectral, and single-crystal X-ray diffraction studies. In complex 1, the ligand 2-hydroxy-1-naphthaldehydethiosemicarbazone coordinated as a monobasic tridentate donor, whereas in complexes 2 and 3, the ligands salicylaldehyde-4(N)-ethylthiosemicarbazone and
Siyue Lou et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 51, 251-258 (2012-09-20)
Nickel, a metal commonly found in battery plants and welding factories, has potential cardiotoxicity, while all-trans retinoid acid (atRA) can promote cardiovascular repair and myocardial recovery. The purpose of this study was to investigate whether atRA could prevent cardiotoxicity induced
Xiaoqiang Guo et al.
Acta biochimica et biophysica Sinica, 44(4), 330-338 (2012-02-10)
Abnormal expression of histone demethylase Jumonji domain-containing protein 1A (JMJD1A) is associated with many kinds of cancers. JMJD1A is also a hypoxic response gene and its expression is regulated by hypoxia-inducible factor-1α (HIF-1α). In this study, we determined the role
Jason Yamada-Hanff et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(38), 15011-15021 (2013-09-21)
Hippocampal CA1 pyramidal neurons are normally quiescent but can fire spontaneously when stimulated by muscarinic agonists. In brain slice recordings from mouse CA1 pyramidal neurons, we examined the ionic basis of this activity using interleaved current-clamp and voltage-clamp experiments. Both
Yu-Ting Kang et al.
International journal of molecular sciences, 21(2) (2020-01-23)
Nickel (Ni), which is a carcinogenic workplace hazard, increases the risk of lung cancer. Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional cytokine that is involved in both angiogenesis and metastasis, but its role in lung cancer is still not clear.
Aaron I Freire et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 89, 259-263 (2012-01-24)
Raman, IR and UV-vis-NIR experiments of formamide (FA) and nickel chloride solutions at different compositions were carried out. The quantitative Raman study at the νCN region shows that 5 FA molecules are coordinated to Ni (II) and the sixth position
Cynthia C Jose et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(40), 14631-14636 (2014-09-24)
Investigations into the genomic landscape of histone modifications in heterochromatic regions have revealed histone H3 lysine 9 dimethylation (H3K9me2) to be important for differentiation and maintaining cell identity. H3K9me2 is associated with gene silencing and is organized into large repressive
Ricardo D Righetto et al.
Nature communications, 11(1), 5101-5101 (2020-10-11)
Urease converts urea into ammonia and carbon dioxide and makes urea available as a nitrogen source for all forms of life except animals. In human bacterial pathogens, ureases also aid in the invasion of acidic environments such as the stomach
Rebekka Kubisch et al.
Sensors (Basel, Switzerland), 12(3), 3370-3393 (2012-06-28)
Pollution of drinking water sources represents a continuously emerging problem in global environmental protection. Novel techniques for real-time monitoring of water quality, capable of the detection of unanticipated toxic and bioactive substances, are urgently needed. In this study, the applicability
Tai-Feng Hung et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(44), 15686-15691 (2015-09-10)
Herein, potential-tunable Na2 Ni1-x Cux Fe(CN)6 nanoparticles with three-dimensional frameworks and large interstitial spaces were synthesized as alternative cathode materials for aqueous sodium-ion batteries by controlling the molar ratio of Ni(II) to Cu(II) at ambient temperature. The influence of the
Abhay K Pandey et al.
Neuroscience letters, 517(2), 128-132 (2012-05-09)
Bisphenol-A (BPA), a toxic chemical from polycarbonate plastics, is known for behavioural and neural abnormalities. These neuro-behavioural changes reflect the changes in neural activity. However the effect of BPA on nerve action potential is not available. Therefore, present investigation was
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