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PHR1231

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Ismail Hewala et al.
Journal of AOAC International, 94(5), 1447-1460 (2011-12-15)
A simple, rapid, and sensitive RP-HPLC method using photodiode array detection was developed and validated for the simultaneous determination of granisetron hydrochloride, 1-methyl-1H-indazole-3-carboxylic acid (the main degradation product of granisetron), sodium benzoate, methylparaben, propylparaben, and 4-hydroxybenzoic acid (the main degradation
Xu Huang et al.
CNS neuroscience & therapeutics, 18(1), 4-13 (2012-01-28)
D-Serine, the endogenous co-agonist of N-methyl-D-aspartate (NMDA) receptors, has been recognized as an important gliotransmitter in the mammalian brain. D-serine has been shown to prevent psychostimulant-induced decrease in hippocampal neurogenesis. However, the mechanism whereby D-serine regulates neurogenesis has not been
Charline Corre et al.
Environmental technology, 33(13-15), 1671-1676 (2012-09-20)
During biological degradation, such as biofiltration of air loaded with volatile organic compounds, the pollutant is passed through a bed packed with a solid medium acting as a biofilm support. To improve microorganism nutritional equilibrium and hence to enhance the
Christian Ciardi et al.
The British journal of nutrition, 107(6), 826-833 (2011-08-02)
Obesity leads to the activation of pro-inflammatory pathways, resulting in a state of low-grade inflammation. Recently, several studies have shown that the exposure to lipopolysaccharide (LPS) could initiate and maintain a chronic state of low-grade inflammation in obese people. As
Sodium Benzoate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 883(1-2), 3566-3567 (2017)
Yumei Dai et al.
Journal of food science, 75(7), M482-M488 (2011-05-04)
Growth of Saccharomyces cerevisiae and Zygosaccharomyces bailii cells was monitored in the presence of sodium benzoate and eugenol alone or combined. The two antimicrobials' concentration, addition order, and timing were varied to determine and quantify any additive inhibitory effect on
Bonnie L Beezhold et al.
Journal of attention disorders, 18(3), 236-241 (2012-04-28)
Sodium benzoate, a common additive in popular beverages, has recently been linked to ADHD. This research examined the relationship between sodium benzoate-rich beverage ingestion and symptoms related to ADHD in college students. College students (N = 475) completed an anonymous
Francesca Mori et al.
Current drug safety, 7(2), 87-91 (2012-08-10)
In Europe amoxicillin plus clavulanic acid is the most commonly prescribed antibiotic and sodium benzoate is contained in the suspension formulation as a preservative. We studied the relevance of sodium benzoate as the culprit agent. In a group of children
Belinda S Lennerz et al.
Molecular genetics and metabolism, 114(1), 73-79 (2014-12-17)
Sodium benzoate is a widely used preservative found in many foods and soft drinks. It is metabolized within mitochondria to produce hippurate, which is then cleared by the kidneys. We previously reported that ingestion of sodium benzoate at the generally
Koichi Takahashi et al.
The Journal of pharmacy and pharmacology, 63(8), 1008-1014 (2011-07-02)
A hydrotropic formulation containing a percutaneous enhancer was developed for the transdermal formulation of a water-soluble drug and the solubilizing mechanisms of a percutaneous enhancer in water by a hydrotropic agent were investigated. The enhancement effect was also compared with
Saurabh Khasnavis et al.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 7(2), 424-435 (2011-06-28)
DJ-1 (PARK7) is a neuroprotective protein that protects cells from oxidative stress. Accordingly, loss-of-function DJ-1 mutations have been linked with a familial form of early onset Parkinson disease. Mechanisms by which DJ-1 level could be enriched in the CNS are
Sonal Dalvi et al.
Applied and environmental microbiology, 80(21), 6664-6676 (2014-08-26)
Arhodomonas sp. strain Seminole was isolated from a crude oil-impacted brine soil and shown to degrade benzene, toluene, phenol, 4-hydroxybenzoic acid (4-HBA), protocatechuic acid (PCA), and phenylacetic acid (PAA) as the sole sources of carbon at high salinity. Seminole is
Clinical and cerebral volumetric effects of sodium benzoate, a D-amino acid oxidase inhibitor, in a drug-naïve patient with major depression.
Chien-Han Lai et al.
Biological psychiatry, 71(4), e9-e10 (2011-12-20)
Guowen Zhang et al.
Food chemistry, 141(1), 41-47 (2013-06-19)
The interaction between sodium benzoate (SB) and calf thymus DNA in simulated physiological buffer (pH 7.4) using acridine orange (AO) dye as a fluorescence probe, was investigated by UV-Vis absorption, fluorescence and circular dichroism (CD) spectroscopy along with DNA melting
Hsien-Yuan Lane et al.
JAMA psychiatry, 70(12), 1267-1275 (2013-10-04)
In addition to dopaminergic hyperactivity, hypofunction of the N-methyl-d-aspartate receptor (NMDAR) has an important role in the pathophysiology of schizophrenia. Enhancing NMDAR-mediated neurotransmission is considered a novel treatment approach. To date, several trials on adjuvant NMDA-enhancing agents have revealed beneficial
Sodium Benzoate
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 38(3)(1-2), 5951-5951 (2018)
Matthew J Palframan et al.
Organic letters, 13(12), 3150-3153 (2011-05-20)
(+)-Grandifloracin was synthesized from sodium benzoate by means of a dearomatizing dihydroxylation that proceeds with unusual regioselectivity. Iron diene complexes formed from the arene oxidation product permit the use of otherwise inaccessible transformations. The synthetic material was shown to be
J L Poo et al.
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 42 Suppl, 101-105 (1990-07-01)
Sodium benzoate is widely used in the Alimentary Industry at low doses for its antimicrobial action. It has also been used as a liver function test. The principle is to evaluate the liver capacity for conjugation of glycine to benzoic
Simultaneous determination of aspartame, acesulfame-K, saccharin, citric acid and sodium benzoate in various food products using HPLC-CAD-UV/DAD
Grembecka M, et al
European Food Research and Technology, 238(3), 357-365 (2014)
Yue Mu et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 83(1), 130-135 (2011-09-06)
The toxicity of sodium benzoate to trypsin was investigated by fluorescence spectroscopy, synchronous fluorescence spectroscopy, UV-visible absorption spectroscopy and circular dichroism (CD) spectroscopy under mimic physiological conditions. Sodium benzoate could unfold trypsin by decreasing the β-sheet structure, which leads to
Sandesh C S Nagamani et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 14(5), 501-507 (2012-01-14)
The urea cycle consists of six consecutive enzymatic reactions that convert waste nitrogen into urea. Deficiencies of any of these enzymes of the cycle result in urea cycle disorders (UCDs), a group of inborn errors of hepatic metabolism that often
Tony Jin et al.
Journal of food science, 76(3), M184-M188 (2011-05-04)
Survival of Escherichia coli O157:H7 and Salmonella Stanley on apples as affected by application of polylactic acid (PLA) coating with antimicrobials was investigated. Golden Delicious apples were spot inoculated with E. coli O157:H7 or S. Stanley and spray coated with PLA solutions containing lactic acid (LA), disodium
Mingqi Xie et al.
Nucleic acids research, 42(14), e116-e116 (2014-07-18)
Synthetic biology has significantly advanced the design of mammalian trigger-inducible transgene-control devices that are able to programme complex cellular behaviour. Fruit-based benzoate derivatives licensed as food additives, such as flavours (e.g. vanillate) and preservatives (e.g. benzoate), are a particularly attractive
Nilesh Jain et al.
Pakistan journal of pharmaceutical sciences, 26(1), 159-162 (2012-12-25)
A novel, eco friendly, accurate, sensitive, economic and safe spectrophotometric method was developed by application of mixed hydrotropy using 2 M sodium acetate, 8 M urea, 2 M niacinamide and 2 M sodium benzoate solution (25:25:25:25% V/V) as hydrotropic agent
Dae Eun Choi et al.
Journal of Korean medical science, 27(5), 556-559 (2012-05-09)
Ornithine carbamoyltransferase (OTC) deficiency is a urea cycle disorder that causes the accumulation of ammonia, which can lead to encephalopathy. Adults presenting with hyperammonemia who are subsequently diagnosed with urea cycle disorders are rare. Herein, we report a case of
Susanta Mondal et al.
PloS one, 10(1), e0116566-e0116566 (2015-01-09)
Upregulation and/or maintenance of regulatory T cells (Tregs) during an autoimmune insult may have therapeutic efficacy in autoimmune diseases. Although several immunomodulatory drugs and molecules are available, most present significant side effects over long-term use. Cinnamon is a commonly used
High-pressure liquid chromatographic assay of dextromethorphan hydrobromide, guaifenesin, and sodium benzoate in an expectorant syrup
Chen TM, et al.
Journal of Chromatographic Science, 26(12), 636-639 (1988)
Teja Gaonkar et al.
TheScientificWorldJournal, 2012, 857249-857249 (2012-05-26)
Bioremediation in natural ecosystems is dependent upon the availability of micronutrients and cofactors, of which iron is one of the essential elements. Under aerobic and alkaline conditions, iron oxidizes to Fe(+3) creating iron deficiency. To acquire this essential growth-limiting nutrient
Trelita de Sousa et al.
Bioresource technology, 123, 256-262 (2012-09-04)
Pseudomonas nitroreducens TSB.MJ10 exhibiting growth and bioemulsifier production with 0.5% sodium benzoate as the sole carbon source was isolated from a mangrove ecosystem in the vicinity of a petroleum pump. The bioemulsifier is a lipopeptide that is stable over a
Jane Pui Ki Tsang et al.
Pediatric neurology, 47(4), 263-269 (2012-09-12)
In areas without expanded newborn screening, instead of presenting neonatally, patients with arginase deficiency typically present with spastic paraplegia in early childhood. Diagnosis of this rare neurometabolic disease poses the first challenge because it is often misdiagnosed as cerebral palsy
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