M Pêco
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 19 Suppl 2, II35-II41 (2001-04-17)
The first application of angiotensin converting enzyme (ACE) inhibitors it was the treatment of arterial hypertension. Latter news application appears such as: heart failure, myocardial infarct, nephropathy and diabetic proteinuria. Captopril, the first oral ACE inhibitor was used, since 1986