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Nobuyasu Okuda et al.
Chemosphere, 114, 59-68 (2014-08-13)
To better understand the infiltration performances of high concentration PCB oils (KC-300 and KC-1000 polychlorinated biphenyl (PCB) mixtures), representative dense non-aqueous phase liquid (DNAPL), under both saturated and unsaturated conditions, we conducted experiments on a sand column filled with Toyoura...
D Święch et al.
Physical chemistry chemical physics : PCCP, 17(35), 22882-22892 (2015-08-13)
The tip-enhanced Raman scattering (TERS) spectra of bradykinin (BK) and its potent B2 BK receptor antagonists, [d-Arg(0),Hyp(3),Thi(5,8),l-Pip(7)]BK and [d-Arg(0),Hyp(3),Thi(5),d-Phe(7),l-Pip(8)]BK, approximately with a size of about 40 nm, adsorbed onto colloidal suspended Ag nanowires with diameter in the range of 350-500...
Antonino Tuttolomondo et al.
Clinical biochemistry, 48(1-2), 55-62 (2014-10-05)
Anderson/Fabry disease expresses a wide range of clinical variability in patients that it is possible to explain referring to a genetic variability with numerous mutations described in the literature (more than 600). We report some clinical cases of some members...
Morgan Solliec et al.
Rapid communications in mass spectrometry : RCM, 29(24), 2361-2373 (2015-11-14)
Swine manure can contain a wide range of veterinary antibiotics, which could enter the environment via manure spreading on agricultural fields. A suspect and non-target screening method was applied to swine manure samples to attempt to identify veterinary antibiotics and...
Tissue electrolytes in dehydrated children.
Nutrition reviews, 25(7), 205-207 (1967-07-01)
Juan Zhou et al.
Clinical and translational gastroenterology, 6, e101-e101 (2015-07-17)
Colorectal cancer initially lies dormant as dysplasia, a premalignant state that provides an opportunity for early cancer detection. Dysplasia can be flat in morphology, focal in size, and patchy in distribution, and thus it appears "invisible" on conventional wide-field endoscopy....
Natália N Saraiva et al.
Natural product research, 29(16), 1545-1550 (2014-12-24)
A fungal strain of Aspergillus sp. (BRF 030) was isolated from the sediments collected in the northeast coast of Brazil, and the cytotoxic activity of its secondary metabolites was investigated against HCT-116 tumour cell line. The cytotoxicity-guided fractionation of the...
Qiang Zhang et al.
Food & function, 6(5), 1518-1525 (2015-03-31)
Flavonoids have been reported to exhibit prooxidant cytotoxicity against cancer cells, but the underlying mechanism is still poorly understood. Here we investigated the potential mechanism that p53-inducible gene 3 (PIG3), a NADPH:quinone oxidoreductase, mediated the prooxidant cytotoxicity of flavonoids on...
Gianluca Lista et al.
Pediatrics, 135(2), e457-e464 (2015-01-28)
Studies suggest that giving newly born preterm infants sustained lung inflation (SLI) may decrease their need for mechanical ventilation (MV) and improve their respiratory outcomes. We randomly assigned infants born at 25 weeks 0 days to 28 weeks 6 days...
Juan A Bonachela et al.
Science (New York, N.Y.), 347(6222), 651-655 (2015-02-07)
Self-organized spatial vegetation patterning is widespread and has been described using models of scale-dependent feedback between plants and water on homogeneous substrates. As rainfall decreases, these models yield a characteristic sequence of patterns with increasingly sparse vegetation, followed by sudden...
Yanli Cui et al.
Carbohydrate research, 407, 51-54 (2015-02-24)
We herein report an efficient synthesis of β-glycosyl 1-ester in room-temperature ionic liquids (RTILs) promoted via silver salt and quaternary ammonium salt (PTC) with good or excellent yields. All products were isolated exclusively as the β-anomers. Four different RTILs, eight...
Bai-Wei Gu et al.
PloS one, 10(5), e0127414-e0127414 (2015-05-21)
Dyskeratosis congenita (DC) is an inherited bone marrow failure syndrome characterized by the presence of short telomeres at presentation. Mutations in ten different genes, whose products are involved in the telomere maintenance pathway, have been shown to cause DC. The...
Francisco Miguel Cardoso et al.
Journal of virology, 88(15), 8278-8296 (2014-05-16)
Influenza virus neuraminidase (NA) is an interesting target of small-molecule antiviral drugs. We isolated a set of H5N1 NA-specific single-domain antibodies (N1-VHHm) and evaluated their in vitro and in vivo antiviral potential. Two of them inhibited the NA activity and...
Roger R Beerli et al.
mAbs, 6(6), 1608-1620 (2014-12-09)
Anti-cytokine autoantibodies have been widely reported to be present in human plasma, both in healthy subjects and in patients with underlying autoimmune conditions, such as autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) or thymic epithelial neoplasms. While often asymptomatic, they can...
Andrew T Lucas et al.
PloS one, 9(11), e112823-e112823 (2014-11-15)
The translationally-controlled tumor protein (TCTP) is a highly conserved, ubiquitously expressed, abundant protein that is broadly distributed among eukaryotes. Its biological function spans numerous cellular processes ranging from regulation of the cell cycle and microtubule stabilization to cell growth, transformation...
Raziye Akcılar et al.
International journal of clinical and experimental medicine, 8(8), 12783-12791 (2015-11-10)
Hypertension is a risk factor for the cardiovascular diseases. Ozone as a therapeutic agent for the treatment of several disorders. We aimed to observe the effects of ozone on the blood pressure in DOCA-salt hypertensive rats. Twenty three young Sprague...
Min-Soo Kim et al.
Canadian journal of anaesthesia = Journal canadien d'anesthesie, 62(9), 979-987 (2015-04-15)
Volume-controlled ventilation with a prolonged inspiratory to expiratory ratio (I:E ratio) has been used to optimize gas exchange and respiratory mechanics in various surgical settings. We hypothesized that, when compared with an I:E ratio of 1:2, a prolonged I:E ratio...
Faiezah A A Mohamed et al.
Drug development and industrial pharmacy, 41(1), 70-78 (2013-10-19)
The particle size of HPMC is a critical factor that can influence drug release rate from hydrophilic matrix systems. Percolation theory is a statistical tool which is used to study the disorder of particles in a lattice of a sample....
Raju V V Tatituri et al.
Analytical and bioanalytical chemistry, 407(9), 2519-2528 (2015-02-07)
Listeria monocytogenes (L. monocytogenes) is a facultative, Gram-positive, food-borne bacterium, which causes serious infections. Although it is known that lipids play important roles in the survival of Listeria, the detailed structures of these lipids have not been established. In this...
Thomas S Postler et al.
PloS one, 9(12), e114753-e114753 (2014-12-06)
Previous studies have shown that truncation of the cytoplasmic-domain sequences of the simian immunodeficiency virus (SIV) envelope glycoprotein (Env) just prior to a potential intracellular-trafficking signal of the sequence YIHF can strongly increase Env protein expression on the cell surface...
Qian Wang et al.
The Journal of pathology, 236(3), 278-289 (2015-02-20)
Glutamine is conditionally essential in cancer cells, being utilized as a carbon and nitrogen source for macromolecule production, as well as for anaplerotic reactions fuelling the tricarboxylic acid (TCA) cycle. In this study, we demonstrated that the glutamine transporter ASCT2...
Arnaud M Wolfer et al.
Analytical chemistry, 87(23), 11721-11731 (2015-10-27)
Lipid mediators, highly bioactive compounds synthesized from polyunsaturated fatty acids (PUFAs), have a fundamental role in the initiation and signaling of the inflammatory response. Although extensively studied in isolation, only a limited number of analytical methods offer a comprehensive coverage...
Junshu Wu et al.
Journal of nanoscience and nanotechnology, 13(8), 5452-5460 (2013-07-26)
A swift and efficient approach to converting organic dye effluents into fresh water could be of substantial benefit. In this study, we presented facile hydrothermal synthesis of K1.33Mn8O16 nanowires in ammonium fluoride (NH4F) aqueous solution. The crystallization process of K1.33Mn8O16...
Gustavo Da Silva et al.
Microscopy research and technique, 78(11), 1001-1009 (2015-08-26)
Gymnosporia arenicola Jordaan (Celastraceae) is a shrub or small tree, which naturally occurs in coastal sand dunes of Southern Mozambique and South Africa. Its dried leaf is often used in traditional medicine for the treatment of infectious and inflammatory diseases....
Martin Babinský et al.
Nucleic acids research, 42(22), 14031-14041 (2014-11-28)
Abasic (AP) lesions are the most frequent type of damages occurring in cellular DNA. Here we describe the conformational effects of AP sites substituted for 2'-deoxyadenosine in the first (ap7), second (ap13) or third (ap19) loop of the quadruplex formed...
Yasuhito Funahashi et al.
The Prostate, 75(4), 381-389 (2014-12-03)
Prostatic inflammation is reportedly associated with the development of prostatic hyperplasia. We investigated the effects of prostatic inflammation on expression levels of androgen-responsive genes and growth factors in the rat prostate. Prostatic inflammation was induced by Escherichia coli (strain 1677)...
Susanne Herbst et al.
EMBO molecular medicine, 7(3), 240-258 (2015-02-01)
Transplant recipients on calcineurin inhibitors are at high risk of invasive fungal infection. Understanding how calcineurin inhibitors impair fungal immunity is a key priority for defining risk of infection. Here, we show that the calcineurin inhibitor tacrolimus impairs clearance of...
Yuan Yan et al.
Anti-cancer drugs, 26(5), 540-546 (2015-02-26)
There is an urgent need to search for novel chemosensitizers in the field of cancer therapy. Chlorogenic acid (CGA), a type of polyphenol present in the diet, has many biological activities. The present study is designed to explore the influence...
Zhenling Wang et al.
Journal of nanoscience and nanotechnology, 14(6), 4506-4512 (2014-04-18)
Water-soluble rare earth ion (Ce3+, Tb3+)-doped LaF3 nanoparticles with the ability to bind to deoxyribonucleic acid (DNA) were prepared by the refluxing method in a glycerol/water mixture and characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), photoluminescence (PL) spectra...
S D Moore-Olufemi et al.
Digestive diseases and sciences, 60(5), 1206-1214 (2014-11-29)
Gastroschisis (GS) is a congenital abdominal wall defect that results in the development of GS-related intestinal dysfunction (GRID). Transforming growth factor-β, a pro-inflammatory cytokine, has been shown to cause organ dysfunction through alterations in vascular and airway smooth muscle. The...
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