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Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives.

Bioorganic & medicinal chemistry (2007-07-10)
Oya Bozdağ-Dündar, Ozen Ozgen, Arzu Menteşe, Nurten Altanlar, Onur Atli, Engin Kendi, Rahmiye Ertan
PMID17618124
ABSTRACT

In this study, a series of thiazolyl thiazolidine-2,4-dione derivatives (Va-f and VIa-f) were synthesized and evaluated for their antibacterial and antifungal activities against Staphylococcus aureus (ATCC 25923), methicillin resistant S. aureus (MRSA ATCC 43300), methicillin resistant S. aureus (MRSA isolate), and Escherichia coli (ATCC 23556) and C. albicans (ATCC10145). All the compounds were found active against used microorganisms.

MATERIALS
Product Number
Brand
Product Description
A9393
Sigma-Aldrich
Ampicillin, anhydrous, 96.0-102.0% (anhydrous basis)
17850
Sigma-Aldrich
Ciprofloxacin, ≥98% (HPLC)
33434
Supelco
Ciprofloxacin, VETRANAL®, analytical standard