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Smqnr, a new chromosome-carried quinolone resistance gene in Stenotrophomonas maltophilia.

Antimicrobial agents and chemotherapy (2008-07-23)
Kenichiro Shimizu, Ken Kikuchi, Takashi Sasaki, Namiko Takahashi, Masayuki Ohtsuka, Yuka Ono, Keiichi Hiramatsu
ABSTRACT

A new chromosome-carried quinolone resistance gene from Stenotrophomonas maltophilia, Smqnr, was characterized. The gene was present in type strain CCUG 5866 and was also detected in 24 clinical isolates and showed some allelic diversity. The expression of Smqnr in Escherichia coli decreased the susceptibilities of the E. coli isolates to several fluoroquinolones.

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