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Antiseptic activity and phenolic constituents of the aerial parts of Vitex negundo var. cannabifolia.

Molecules (Basel, Switzerland) (2010-11-23)
Tie-Jun Ling, Wei-Wei Ling, Yuan-Jun Chen, Xiao-Chun Wan, Tao Xia, Xian-Feng Du, Zheng-Zhu Zhang
ABSTRACT

Four phenolics, salviaplebeiaside (1), γ-tocopherol (2), chrysosplenol-D (4), and isovitexin (5), along with α-tocoquinone (3) and β-sitosterol (6) were isolated from the aerial parts of Vitex negundo var. cannabifolia. The isolation was performed using bio-assay tracking experiments. The structures of compounds 1-5 were established by spectroscopic means. The antibacterial activities of the compounds were assessed against Escherichia coli, Bacillus subtilis, Micrococcus tetragenus and Pseudomonas fluorescens. Chrysosplenol-D (4) exhibited activities against all the four spoilage microorganisms.

MATERIALS
Product Number
Brand
Product Description

Supelco
Isovitexin, analytical standard
Sigma-Aldrich
Isovitexin, ≥98.0% (HPLC)
Isovitexin, primary reference standard