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Reduction of MOPEG levels in cerebrospinal fluid of psychotic women after electroconvulsive treatment.

Psychopharmacology (1979-08-08)
C Härnryd, L Bjerkenstedt, V E Grimm, G Sedvall
PMID115032
ABSTRACT

The effect of ECT on concentrations of monoamine metabolites in lumbar CSF of psychotic women with a schizophrenic symptomatology was examined. After a series of ECT there was a significant reduction of the concentration of the major noradrenaline metabolite, MOPEG. Levels of HVA, 5-HIAA, prolactin, or total protein in CSF were not significantly influenced by treatment. The results indicate a specific alteration of central noradrenaline metabolism in relation to ECT.

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