Merck
  • Copper-catalyzed oxidative decarboxylative couplings of sulfoximines and aryl propiolic acids.

Copper-catalyzed oxidative decarboxylative couplings of sulfoximines and aryl propiolic acids.

Organic letters (2013-11-28)
Daniel L Priebbenow, Peter Becker, Carsten Bolm
ABSTRACT

A method has been developed for the preparation of N-alkynylated sulfoximines involving the copper-catalyzed decarboxylative coupling of sulfoximines with aryl propiolic acids. A range of substituents on both the sulfoximidoyl moiety and the aryl group of the propiolic acid were compatible with this reaction process to afford a series of sulfoximidoyl-functionalized alkynes.

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