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Where bio meets nano: the many uses for nanoporous aluminum oxide in biotechnology.

Biotechnology advances (2011-08-23)
Colin J Ingham, Jurjen ter Maat, Willem M de Vos
ABSTRACT

Porous aluminum oxide (PAO) is a ceramic formed by an anodization process of pure aluminum that enables the controllable assembly of exceptionally dense and regular nanopores in a planar membrane. As a consequence, PAO has a high porosity, nanopores with high aspect ratio, biocompatibility and the potential for high sensitivity imaging and diverse surface modifications. These properties have made this unusual material attractive to a disparate set of applications. This review examines how the structure and properties of PAO connect with its present and potential uses within research and biotechnology. The role of PAO is covered in areas including microbiology, mammalian cell culture, sensitive detection methods, microarrays and other molecular assays, and in creating new nanostructures with further uses within biology.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
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Supelco
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Sigma-Aldrich
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Sigma-Aldrich
Aluminum oxide, nanowires, diam. × L 2-6 nm × 200-400 nm
Sigma-Aldrich
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Supelco
Aluminum oxide, for the determination of hydrocarbons
Sigma-Aldrich
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Sigma-Aldrich
Aluminum oxide, nanoparticles, 30-60 nm particle size (TEM), 20 wt. % in H2O
Sigma-Aldrich
Aluminum oxide, nanoparticles, <50 nm particle size (DLS), 20 wt. % in isopropanol
Sigma-Aldrich
Aluminum oxide, single crystal substrate, <0001>
Sigma-Aldrich
Aluminum oxide, activated, neutral, Brockmann I
Sigma-Aldrich
Aluminum oxide, activated, basic, Brockmann I
Sigma-Aldrich
Aluminum oxide, Type WN-6, Neutral, Activity Grade Super I
Sigma-Aldrich
Aluminum oxide, puriss., ≥98% Al2O3 basis
Sigma-Aldrich
Aluminum oxide, activated, acidic, Brockmann I
Sigma-Aldrich
Aluminum oxide, pore size 58 Å, ~150 mesh
Sigma-Aldrich
Aluminum oxide, powder, primarily α phase, ≤10 μm avg. part. size, 99.5% trace metals basis
Sigma-Aldrich
Aluminum oxide, Type CG-20
Sigma-Aldrich
Aluminum oxide, fused, powder, primarily α-phase, 100-200 mesh
Sigma-Aldrich
Aluminum oxide, calcined, powder, primarily α-phase, 100-325 mesh
Sigma-Aldrich
Aluminum oxide, Corundum, α-phase, -100 mesh
Sigma-Aldrich
Aluminum oxide, fused, powder, primarily α-phase, -325 mesh
Sigma-Aldrich
Aluminum oxide, powder, 99.99% trace metals basis
Sigma-Aldrich
Aluminum oxide, activated, acidic, Brockmann I, free-flowing, Redi-Dri
Sigma-Aldrich
Aluminum oxide, activated, neutral, Brockmann I, free-flowing, Redi-Dri
Sigma-Aldrich
Aluminum oxide, pellets, 3 mm