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Effects of aspartame and phenylalanine on meal-time food intake of humans.

Appetite (1988-01-01)
G H Anderson, L A Leiter
ABSTRACT

This article reviews data relevant to the hypothesis that aspartame may have a unique effect on meal-time food intake regulation due to its amino acid composition and in addition to its effects as a high intensity sweetener. It is concluded that future studies involving aspartame should be directed towards developing a fundamental understanding of the effects of high intensity sweeteners on food intake, and not give undue attention to putative actions based on its amino acid constituents.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Asp-Phe methyl ester, ≥98%
Supelco
Aspartame, analytical standard
USP
Aspartame, United States Pharmacopeia (USP) Reference Standard
Aspartame, European Pharmacopoeia (EP) Reference Standard
Supelco
Aspartame, Pharmaceutical Secondary Standard; Certified Reference Material