Merck

Does sucrose or aspartame cause hyperactivity in children?

Nutrition reviews (1994-05-01)
R B Kanarek
ABSTRACT

Anecdotal evidence has led to the hypothesis that there is a relationship between sugar intake and hyperactive behavior. To assess this hypothesis, a recent study using a range of behavioral and cognitive measures evaluated the effects of diets high in sucrose, aspartame, and saccharin on the performance of school-aged children believed to be sensitive to sugar, and preschool children. Although intakes exceeded average dietary levels, neither sucrose nor aspartame negatively affected behavior. Taken together with previous work, these results indicate that sugar is not a major cause of hyperactivity.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Asp-Phe methyl ester, ≥98%
Supelco
Aspartame, analytical standard
Aspartame, European Pharmacopoeia (EP) Reference Standard
Supelco
Aspartame, Pharmaceutical Secondary Standard; Certified Reference Material
USP
Aspartame, United States Pharmacopeia (USP) Reference Standard